3JD2
| Glutamate dehydrogenase in complex with NADH, open conformation | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Glutamate dehydrogenase 1, mitochondrial | 著者 | Borgnia, M.J, Banerjee, S, Merk, A, Matthies, D, Bartesaghi, A, Rao, P, Pierson, J, Earl, L.A, Falconieri, V, Subramaniam, S, Milne, J.L.S. | 登録日 | 2016-03-28 | 公開日 | 2016-04-27 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase. Mol.Pharmacol., 89, 2016
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3DNO
| Molecular structure for the HIV-1 gp120 trimer in the CD4-bound state | 分子名称: | HIV-1 envelope glycoprotein gp120 | 著者 | Borgnia, M.J, Liu, J, Bartesaghi, A, Sapiro, G, Subramaniam, S. | 登録日 | 2008-07-02 | 公開日 | 2008-08-19 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (20 Å) | 主引用文献 | Molecular architecture of native HIV-1 gp120 trimers. Nature, 455, 2008
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3DNN
| Molecular structure for the HIV-1 gp120 trimer in the unliganded state | 分子名称: | HIV-1 envelope glycoprotein gp120 | 著者 | Borgnia, M.J, Liu, J, Bartesaghi, A, Sapiro, G, Subramaniam, S. | 登録日 | 2008-07-02 | 公開日 | 2008-08-19 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (20 Å) | 主引用文献 | Molecular architecture of native HIV-1 gp120 trimers. Nature, 455, 2008
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3DNL
| Molecular structure for the HIV-1 gp120 trimer in the b12-bound state | 分子名称: | HIV-1 envelope glycoprotein gp120 | 著者 | Borgnia, M.J, Liu, J, Bartesaghi, A, Sapiro, G, Subramaniam, S. | 登録日 | 2008-07-02 | 公開日 | 2008-08-19 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (20 Å) | 主引用文献 | Molecular architecture of native HIV-1 gp120 trimers. Nature, 455, 2008
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3JD4
| Glutamate dehydrogenase in complex with NADH and GTP, closed conformation | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GUANOSINE-5'-TRIPHOSPHATE, Glutamate dehydrogenase 1, ... | 著者 | Borgnia, M.J, Banerjee, S, Merk, A, Matthies, D, Bartesaghi, A, Rao, P, Pierson, J, Earl, L.A, Falconieri, V, Subramaniam, S, Milne, J.L.S. | 登録日 | 2016-03-28 | 公開日 | 2016-04-27 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase. Mol.Pharmacol., 89, 2016
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3JD1
| Glutamate dehydrogenase in complex with NADH, closed conformation | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Glutamate dehydrogenase 1, mitochondrial | 著者 | Borgnia, M.J, Banerjee, S, Merk, A, Matthies, D, Bartesaghi, A, Rao, P, Pierson, J, Earl, L.A, Falconieri, V, Subramaniam, S, Milne, J.L.S. | 登録日 | 2016-03-28 | 公開日 | 2016-04-27 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase. Mol.Pharmacol., 89, 2016
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3JD3
| Glutamate dehydrogenase in complex with NADH and GTP, open conformation | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GUANOSINE-5'-TRIPHOSPHATE, Glutamate dehydrogenase 1, ... | 著者 | Borgnia, M.J, Banerjee, S, Merk, A, Matthies, D, Bartesaghi, A, Rao, P, Pierson, J, Earl, L.A, Falconieri, V, Subramaniam, S, Milne, J.L.S. | 登録日 | 2016-03-28 | 公開日 | 2016-04-27 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase. Mol.Pharmacol., 89, 2016
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3JD0
| Glutamate dehydrogenase in complex with GTP | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Glutamate dehydrogenase 1, mitochondrial | 著者 | Borgnia, M.J, Banerjee, S, Merk, A, Matthies, D, Bartesaghi, A, Rao, P, Pierson, J, Earl, L.A, Falconieri, V, Subramaniam, S, Milne, J.L.S. | 登録日 | 2016-03-28 | 公開日 | 2016-04-27 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase. Mol.Pharmacol., 89, 2016
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3JCZ
| Structure of bovine glutamate dehydrogenase in the unliganded state | 分子名称: | Glutamate dehydrogenase 1, mitochondrial | 著者 | Borgnia, M.J, Banerjee, S, Merk, A, Matthies, D, Bartesaghi, A, Rao, P, Pierson, J, Earl, L.A, Falconieri, V, Subramaniam, S, Milne, J.L.S. | 登録日 | 2016-03-27 | 公開日 | 2016-04-27 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase. Mol.Pharmacol., 89, 2016
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6NN6
| Structure of Dot1L-H2BK120ub nucleosome complex | 分子名称: | DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Anderson, C.J, Baird, M.R, Hsu, A, Barbour, E.H, Koyama, Y, Borgnia, M.J, McGinty, R.K. | 登録日 | 2019-01-14 | 公開日 | 2019-02-13 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase. Cell Rep, 26, 2019
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6NR4
| Cryo-EM structure of the TRPM8 ion channel with low occupancy icilin, PI(4,5)P2, and calcium | 分子名称: | Transient receptor potential cation channel subfamily M member 8 | 著者 | Yin, Y, Le, S.C, Hsu, A.L, Borgnia, M.J, Yang, H, Lee, S.-Y. | 登録日 | 2019-01-22 | 公開日 | 2019-02-20 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel. Science, 363, 2019
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6NR2
| Cryo-EM structure of the TRPM8 ion channel in complex with the menthol analog WS-12 and PI(4,5)P2 | 分子名称: | (1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-(propan-2-yl)cyclohexane-1-carboxamide, (2S)-1-{[(R)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl icosa-5,8,11,14-tetraenoate, Transient receptor potential cation channel subfamily M member 8 | 著者 | Yin, Y, Le, S.C, Hsu, A.L, Borgnia, M.J, Yang, H, Lee, S.-Y. | 登録日 | 2019-01-22 | 公開日 | 2019-02-20 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel. Science, 363, 2019
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7TQV
| SARS-CoV-2 endoribonuclease Nsp15 bound to dsRNA | 分子名称: | RNA (33-MER), Uridylate-specific endoribonuclease | 著者 | Frazier, M.N, Krahn, J.M, Butay, K.J, Dillard, L.B, Borgnia, M.J, Stanley, R.E. | 登録日 | 2022-01-27 | 公開日 | 2022-03-23 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (3.43 Å) | 主引用文献 | Flipped over U: structural basis for dsRNA cleavage by the SARS-CoV-2 endoribonuclease. Nucleic Acids Res., 50, 2022
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7TPR
| Camel nanobodies 7A3 and 8A2 broadly neutralize SARS-CoV-2 variants | 分子名称: | Nanobody 7A3, Nanobody 8A2, Spike glycoprotein | 著者 | Butay, K.J, Zhu, J, Dandey, V.P, Hong, J, Kwon, H.J, Chen, C.Z, Duan, Z, Li, D, Ren, H, Liang, T, Martin, N, Esposito, D, Ortega-Rodriguez, U, Xu, M, Xie, H, Ho, M, Cachau, R, Borgnia, M.J. | 登録日 | 2022-01-25 | 公開日 | 2022-04-20 | 実験手法 | ELECTRON MICROSCOPY (2.39 Å) | 主引用文献 | Camel nanobodies broadly neutralize SARS-CoV-2 variants bioRxiv, 2021
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7TU6
| Structure of the L. blandensis dGTPase bound to dATP | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, dGTP triphosphohydrolase | 著者 | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | 登録日 | 2022-02-02 | 公開日 | 2022-06-01 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298, 2022
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7TU7
| Structure of the L. blandensis dGTPase H125A mutant bound to dGTP | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, dGTP triphosphohydrolase | 著者 | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | 登録日 | 2022-02-02 | 公開日 | 2022-06-01 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298, 2022
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7TU8
| Structure of the L. blandensis dGTPase H125A mutant bound to dGTP and dATP | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | 登録日 | 2022-02-02 | 公開日 | 2022-06-01 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298, 2022
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7TU5
| Structure of the L. blandensis dGTPase in the apo form | 分子名称: | MAGNESIUM ION, dGTP triphosphohydrolase | 著者 | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | 登録日 | 2022-02-02 | 公開日 | 2022-06-01 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | 主引用文献 | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298, 2022
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6MAT
| Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Rix7 mutant, unknown protein | 著者 | Lo, Y.H, Sobhany, M, Hsu, A.L, Ford, B.L, Krahn, J.M, Borgnia, M.J, Stanley, R.E. | 登録日 | 2018-08-28 | 公開日 | 2019-02-06 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7. Nat Commun, 10, 2019
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4CC8
| Pre-fusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy | 分子名称: | GP120, GP41, MONOCLONAL ANTIBODY VRC03 FAB HEAVY CHAIN, ... | 著者 | Bartesaghi, A, Merk, A, Borgnia, M.J, Milne, J.L.S, Subramaniam, S. | 登録日 | 2013-10-18 | 公開日 | 2013-10-30 | 最終更新日 | 2018-01-10 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | Prefusion Structure of Trimeric HIV-1 Envelope Glycoprotein Determined by Cryo-Electron Microscopy. Nat.Struct.Mol.Biol., 20, 2013
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6NR3
| Cryo-EM structure of the TRPM8 ion channel in complex with high occupancy icilin, PI(4,5)P2, and calcium | 分子名称: | (2S)-1-{[(R)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl icosa-5,8,11,14-tetraenoate, CALCIUM ION, Icilin, ... | 著者 | Yin, Y, Le, S.C, Hsu, A.L, Borgnia, M.J, Yang, H, Lee, S.-Y. | 登録日 | 2019-01-22 | 公開日 | 2019-02-20 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel. Science, 363, 2019
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7U67
| Structure of E. coli dGTPase bound to T7 bacteriophage protein Gp1.2 and GTP | 分子名称: | Deoxyguanosinetriphosphate triphosphohydrolase, GUANOSINE-5'-TRIPHOSPHATE, Inhibitor of dGTPase, ... | 著者 | Klemm, B.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | 登録日 | 2022-03-03 | 公開日 | 2022-08-31 | 最終更新日 | 2022-09-21 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase. Proc.Natl.Acad.Sci.USA, 119, 2022
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7U66
| Structure of E. coli dGTPase bound to T7 bacteriophage protein Gp1.2 and dGTP | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxyguanosinetriphosphate triphosphohydrolase, Inhibitor of dGTPase, ... | 著者 | Klemm, B.P, Dillard, L.B, Borgnia, M.J, Schaaper, R.M. | 登録日 | 2022-03-03 | 公開日 | 2022-08-31 | 最終更新日 | 2022-09-21 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase. Proc.Natl.Acad.Sci.USA, 119, 2022
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7U65
| Structure of E. coli dGTPase bound to T7 bacteriophage protein Gp1.2 | 分子名称: | Deoxyguanosinetriphosphate triphosphohydrolase, Inhibitor of dGTPase | 著者 | Klemm, B.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | 登録日 | 2022-03-03 | 公開日 | 2022-08-31 | 最終更新日 | 2022-09-21 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase. Proc.Natl.Acad.Sci.USA, 119, 2022
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7MK2
| CryoEM Structure of NPR1 | 分子名称: | Regulatory protein NPR1, ZINC ION | 著者 | Kumar, S, Zhou, Y, Dillard, L, Borgnia, M, Bartesaghi, A, Zhou, P. | 登録日 | 2021-04-21 | 公開日 | 2022-03-16 | 最終更新日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural basis of NPR1 in activating plant immunity. Nature, 605, 2022
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