7TU8
Structure of the L. blandensis dGTPase H125A mutant bound to dGTP and dATP
Summary for 7TU8
| Entry DOI | 10.2210/pdb7tu8/pdb |
| EMDB information | 26126 26127 26128 26129 |
| Descriptor | dGTP triphosphohydrolase, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ... (4 entities in total) |
| Functional Keywords | dgtpase, nucleotide binding, hydrolase |
| Biological source | Leeuwenhoekiella blandensis MED217 |
| Total number of polymer chains | 6 |
| Total formula weight | 322218.89 |
| Authors | Klemm, B.P.,Sikkema, A.P.,Hsu, A.L.,Borgnia, M.J.,Schaaper, R.M. (deposition date: 2022-02-02, release date: 2022-06-01, Last modification date: 2024-02-21) |
| Primary citation | Klemm, B.P.,Sikkema, A.P.,Hsu, A.L.,Horng, J.C.,Hall, T.M.T.,Borgnia, M.J.,Schaaper, R.M. High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298:102073-102073, 2022 Cited by PubMed: 35643313DOI: 10.1016/j.jbc.2022.102073 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.6 Å) |
Structure validation
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