2Q66
 
 | | Structure of Yeast Poly(A) Polymerase with ATP and oligo(A) | | Descriptor: | 1,2-ETHANEDIOL, 5'-R(P*AP*AP*AP*AP*A)-3', ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Bohm, A, Balbo, P. | | Deposit date: | 2007-06-04 | | Release date: | 2007-08-28 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Mechanism of poly(A) polymerase: structure of the enzyme-MgATP-RNA ternary complex and kinetic analysis.
Structure, 15, 2007
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3MI7
 | | An Enhanced Repressor of Human Papillomavirus E2 Protein | | Descriptor: | 1,2-ETHANEDIOL, Regulatory protein E2 | | Authors: | Bohm, A, Baleja, J, Bose, K, Meinke, G. | | Deposit date: | 2010-04-09 | | Release date: | 2011-04-06 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Design and characterization of an enhanced repressor of human papillomavirus E2 protein.
Faseb J., 25, 2011
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3C66
 | | Yeast poly(A) polymerase in complex with Fip1 residues 80-105 | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Poly(A) polymerase, ... | | Authors: | Bohm, A, Meinke, G. | | Deposit date: | 2008-02-02 | | Release date: | 2008-05-20 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of yeast poly(A) polymerase in complex with a peptide from Fip1, an intrinsically disordered protein.
Biochemistry, 47, 2008
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4FB3
 | | Polyomavirus T-ag binds symmetrical repeats at the viral origin in an asymmetrical manner | | Descriptor: | Large T antigen, ORI DNA oligonucleotide-Crick strand, ORI DNA oligonucleotide-Watson strand | | Authors: | Bohm, A, Harrison, C.J, Schaffhausen, B.S, Jiang, T. | | Deposit date: | 2012-05-22 | | Release date: | 2013-10-23 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.79 Å) | | Cite: | Polyomavirus large T antigen binds symmetrical repeats at the viral origin in an asymmetrical manner.
J.Virol., 87, 2013
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2NTC
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1HMC
 | | THREE-DIMENSIONAL STRUCTURE OF DIMERIC HUMAN RECOMBINANT MACROPHAGE COLONY STIMULATING FACTOR | | Descriptor: | HUMAN MACROPHAGE COLONY STIMULATING FACTOR | | Authors: | Bohm, A, Pandit, J, Jancarik, J, Halenbeck, R, Koths, K, Kim, S.-H. | | Deposit date: | 1993-12-22 | | Release date: | 1994-04-30 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Three-dimensional structure of dimeric human recombinant macrophage colony-stimulating factor.
Science, 258, 1992
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2O1P
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2HHP
 | | Structure of yeast poly(A) polymerase in a closed conformation. | | Descriptor: | CITRATE ANION, MAGNESIUM ION, Poly(A) polymerase | | Authors: | Bohm, A, Toth, J. | | Deposit date: | 2006-06-28 | | Release date: | 2007-01-23 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | X-ray crystallographic and steady state fluorescence characterization of the protein dynamics of yeast polyadenylate polymerase.
J.Mol.Biol., 366, 2007
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3BJ9
 | | Crystal structure of the Surrogate Light Chain Variable Domain VpreBJ | | Descriptor: | 1,2-ETHANEDIOL, Immunoglobulin iota chain, Immunoglobulin lambda-like polypeptide 1 | | Authors: | Morstadt, L.M, Bohm, A.A, Stollar, B.D, Baleja, J.D. | | Deposit date: | 2007-12-03 | | Release date: | 2008-03-04 | | Last modified: | 2019-09-04 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Engineering and characterization of a single chain surrogate light chain variable domain.
Protein Sci., 17, 2008
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5UM4
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1S26
 | | Structure of Anthrax Edema Factor-Calmodulin-alpha,beta-methyleneadenosine 5'-triphosphate Complex Reveals an Alternative Mode of ATP Binding to the Catalytic Site | | Descriptor: | CALCIUM ION, Calmodulin, Calmodulin-sensitive adenylate cyclase, ... | | Authors: | Shen, Y, Zhukovskaya, N.L, Bohm, A, Tang, W.-J. | | Deposit date: | 2004-01-08 | | Release date: | 2004-04-13 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of anthrax edema factor-calmodulin-adenosine-5'-(alpha,beta-methylene)-triphosphate complex reveals an alternative mode of ATP binding to the catalytic site
Biochem.Biophys.Res.Commun., 317, 2004
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1TBG
 | | BETA-GAMMA DIMER OF THE HETEROTRIMERIC G-PROTEIN TRANSDUCIN | | Descriptor: | TRANSDUCIN | | Authors: | Sondek, J.S, Bohm, A, Lambright, D.G, Hamm, H.E, Sigler, P.B. | | Deposit date: | 1996-06-15 | | Release date: | 1997-04-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of a G-protein beta gamma dimer at 2.1A resolution.
Nature, 379, 1996
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5U91
 | | Crystal structure of Tre/loxLTR complex | | Descriptor: | DNA (37-MER), Tre recombinase protein | | Authors: | Meinke, G, Karpinski, J, Buchholz, F, Bohm, A. | | Deposit date: | 2016-12-15 | | Release date: | 2017-07-26 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.104 Å) | | Cite: | Crystal structure of an engineered, HIV-specific recombinase for removal of integrated proviral DNA.
Nucleic Acids Res., 45, 2017
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1GOT
 | | HETEROTRIMERIC COMPLEX OF A GT-ALPHA/GI-ALPHA CHIMERA AND THE GT-BETA-GAMMA SUBUNITS | | Descriptor: | GT-ALPHA/GI-ALPHA CHIMERA, GT-BETA, GT-GAMMA, ... | | Authors: | Lambright, D.G, Sondek, J, Bohm, A, Skiba, N.P, Hamm, H.E, Sigler, P.B. | | Deposit date: | 1996-08-07 | | Release date: | 1997-03-12 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The 2.0 A crystal structure of a heterotrimeric G protein.
Nature, 379, 1996
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5CYN
 | | JC Virus large T-antigen origin binding domain F258L mutant | | Descriptor: | 1,2-ETHANEDIOL, Large T antigen | | Authors: | Meinke, G, Bohm, A, Bullock, P.A. | | Deposit date: | 2015-07-30 | | Release date: | 2015-12-16 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural Based Analyses of the JC Virus T-Antigen F258L Mutant Provides Evidence for DNA Dependent Conformational Changes in the C-Termini of Polyomavirus Origin Binding Domains.
Plos Pathog., 12, 2016
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2TRC
 | | PHOSDUCIN/TRANSDUCIN BETA-GAMMA COMPLEX | | Descriptor: | GADOLINIUM ATOM, PHOSDUCIN, TRANSDUCIN | | Authors: | Gaudet, R, Bohm, A, Sigler, P.B. | | Deposit date: | 1997-01-06 | | Release date: | 1997-06-05 | | Last modified: | 2019-08-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin.
Cell(Cambridge,Mass.), 87, 1996
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5D9I
 | | SV40 Large T antigen origin binding domain bound to artificial DNA fork | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | | Authors: | Meinke, G, Bohm, A, Bullock, P.A. | | Deposit date: | 2015-08-18 | | Release date: | 2015-09-09 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure-based analysis of the interaction between the simian virus 40 T-antigen origin binding domain and single-stranded DNA.
J. Virol., 85, 2011
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4LIF
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4LMD
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1FA0
 | | STRUCTURE OF YEAST POLY(A) POLYMERASE BOUND TO MANGANATE AND 3'-DATP | | Descriptor: | 3'-DEOXYADENOSINE, 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... | | Authors: | Bard, J, Zhelkovsky, A.M, Helmling, S, Moore, C.L, Bohm, A. | | Deposit date: | 2000-07-11 | | Release date: | 2000-08-30 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of yeast poly(A) polymerase alone and in complex with 3'-dATP.
Science, 289, 2000
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4NBP
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3QFQ
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3QGJ
 | | 1.3A Structure of alpha-Lytic Protease Bound to Ac-AlaAlaPro-Alanal | | Descriptor: | 1,2-ETHANEDIOL, Ac-AlaAlaPro-Alanal peptide, Alpha-lytic protease, ... | | Authors: | Everill, P, Meinke, G, Bohm, A, Bachovchin, W. | | Deposit date: | 2011-01-24 | | Release date: | 2012-02-01 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Substrate Binding Defines Ser195 Position in the Catalytic Triad of Serine Proteases, Not His57 protonation
To be Published
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3QK2
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1K93
 | | Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin | | Descriptor: | CALCIUM ION, CALMODULIN, CALMODULIN-SENSITIVE ADENYLATE CYCLASE, ... | | Authors: | Drum, C.L, Yan, S.-Z, Bard, J, Shen, Y.-Q, Lu, D, Soelaiman, S, Grabarek, Z, Bohm, A, Tang, W.-J. | | Deposit date: | 2001-10-26 | | Release date: | 2002-01-23 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.
Nature, 415, 2002
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