4NBP
Crystal structure of the JCV large T-antigen origin binding domain
Summary for 4NBP
Entry DOI | 10.2210/pdb4nbp/pdb |
Related | 4LIF 4LMD |
Descriptor | Large T antigen, L(+)-TARTARIC ACID (3 entities in total) |
Functional Keywords | origin binding domain, dna replication, binds dna, hydrolase |
Biological source | JC polyomavirus (JCPyV) |
Cellular location | Host nucleus (By similarity): P03072 |
Total number of polymer chains | 1 |
Total formula weight | 15470.56 |
Authors | Meinke, G.,Bohm, A.,Bullock, P. (deposition date: 2013-10-23, release date: 2014-03-05, Last modification date: 2014-04-02) |
Primary citation | Meinke, G.,Phelan, P.J.,Kalekar, R.,Shin, J.,Archambault, J.,Bohm, A.,Bullock, P.A. Insights into the Initiation of JC Virus DNA Replication Derived from the Crystal Structure of the T-Antigen Origin Binding Domain. Plos Pathog., 10:e1003966-e1003966, 2014 Cited by PubMed: 24586168DOI: 10.1371/journal.ppat.1003966 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.315 Å) |
Structure validation
Download full validation report