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4NBP

Crystal structure of the JCV large T-antigen origin binding domain

Functional Information from GO Data
ChainGOidnamespacecontents
A0003688molecular_functionDNA replication origin binding
A0006260biological_processDNA replication
Functional Information from PDB Data
site_idAC1
Number of Residues8
DetailsBINDING SITE FOR RESIDUE TLA A 301
ChainResidue
AGLU167
ALYS168
ALEU216
ACYS217
ATHR218
APHE219
ASER220
AHOH591

site_idAC2
Number of Residues8
DetailsBINDING SITE FOR RESIDUE TLA A 302
ChainResidue
AARG203
AHIS204
AALA208
AHOH409
AHOH418
AHOH437
AHOH487
AHIS202

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues115
DetailsDNA_BIND: T-ag OBD => ECO:0000255|PROSITE-ProRule:PRU00620
ChainResidueDetails
APRO140-GLU255

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PDB entries from 2024-11-13

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