Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 243 results

7QAV
DownloadVisualize
BU of 7qav by Molmil
Crystal structure of PqsR (MvfR) ligand-binding domain in complex with compound N-((2-(4-cyclopropylphenyl)thiazol-5-yl)methyl)-2-(trifluoromethyl)pyridin-4-amine
Descriptor: Multiple virulence factor regulator MvfR, ~{N}-[[2-(4-cyclopropylphenyl)-1,3-thiazol-5-yl]methyl]-2-(trifluoromethyl)pyridin-4-amine
Authors:Schmelz, S, Blankenfeldt, W.
Deposit date:2021-11-17
Release date:2022-11-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Divergent Synthesis and Biological Evaluation of inverse agonists targeting PqsR
To Be Published
7QA3
DownloadVisualize
BU of 7qa3 by Molmil
Crystal structure of PqsR (MvfR) ligand-binding domain in complex with compound N-((2-(4-phenoxyphenyl)thiazol-5-yl)methyl)-2-(trifluoromethyl)pyridin-4-amine
Descriptor: Multiple virulence factor regulator MvfR, N-[[2-(4-phenoxyphenyl)-1,3-thiazol-5-yl]methyl]-2-(trifluoromethyl)pyridin-4-amine
Authors:Schmelz, S, Blankenfeldt, W.
Deposit date:2021-11-15
Release date:2022-11-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Divergent Synthesis and Biological Evaluation of inverse agonists targeting PqsR
To Be Published
7NBW
DownloadVisualize
BU of 7nbw by Molmil
Crystal structure of PqsR (MvfR) ligand-binding domain in complex with a pyridin agonist
Descriptor: Transcriptional regulator MvfR, ~{N}-[3-(4-fluorophenyl)prop-2-ynyl]-2-(trifluoromethyl)pyridin-4-amine
Authors:Schmelz, S, Blankenfeldt, W.
Deposit date:2021-01-28
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Divergent synthesis and biological evaluation of 2-(trifluoromethyl)pyridines as virulence-attenuating inverse agonists targeting PqsR.
Eur.J.Med.Chem., 226, 2021
8BRQ
DownloadVisualize
BU of 8brq by Molmil
Crystal structure of a surface entropy reduction variant of penicillin G acylase from Bacillaceae i. s. sp. FJAT-27231
Descriptor: (R,R)-2,3-BUTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Wichmann, J, Mayer, J, Mattes, H, Lukat, P, Blankenfeldt, W, Biedendieck, R.
Deposit date:2022-11-23
Release date:2023-05-03
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Multistep Engineering of a Penicillin G Acylase for Systematic Improvement of Crystallization Efficiency
Cryst.Growth Des., 2023
5JGK
DownloadVisualize
BU of 5jgk by Molmil
Crystal structure of GtmA in complex with SAH
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, UbiE/COQ5 family methyltransferase, ...
Authors:Dolan, S.K, Bock, T, Hering, V, Jones, G.W, Blankenfeldt, W, Dolye, S.
Deposit date:2016-04-20
Release date:2017-03-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Structural, mechanistic and functional insight into gliotoxinbis-thiomethylation inAspergillus fumigatus.
Open Biol, 7, 2017
5JGJ
DownloadVisualize
BU of 5jgj by Molmil
Crystal structure of GtmA
Descriptor: UbiE/COQ5 family methyltransferase, putative
Authors:Dolan, S.K, Bock, T, Hering, V, Jones, G.W, Blankenfeldt, W, Doyle, S.
Deposit date:2016-04-20
Release date:2017-03-01
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structural, mechanistic and functional insight into gliotoxinbis-thiomethylation inAspergillus fumigatus.
Open Biol, 7, 2017
7ZPN
DownloadVisualize
BU of 7zpn by Molmil
Crystal Structure of IscR from Dinoroseobacter shibae
Descriptor: GLYCEROL, HTH-type transcriptional regulator, SULFATE ION
Authors:Lukat, P, Ploetzky, L, Blankenfeldt, W, Jahn, D, Haertig, E.
Deposit date:2022-04-28
Release date:2023-04-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Dinoroseobacter shibae IscR homolog acts as a repressor for iron acquisition genes
To Be Published
8AID
DownloadVisualize
BU of 8aid by Molmil
Crystal structure of N-terminally truncated PA4183 from P. aeruginosa PAO1
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, PA4183
Authors:Popp, M.A, Blankenfeldt, W.
Deposit date:2022-07-26
Release date:2022-11-30
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structure of N-terminally truncated PA4183 from P. aeruginosa PAO1
To Be Published
8BCI
DownloadVisualize
BU of 8bci by Molmil
Crystal structure of short-chain dehydrogenase PA3128 from Pseudomonas aeruginosa PAO1
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Probable short-chain dehydrogenase
Authors:Popp, M.A, Vit, A, Blankenfeldt, W.
Deposit date:2022-10-16
Release date:2022-11-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The structure of short-chain dehydrogenase PA3128 from Pseudomonas aeruginosa PAO1
To Be Published
8BCJ
DownloadVisualize
BU of 8bcj by Molmil
Crystal structure of short-chain dehydrogenase PA3128 from Pseudomonas aeruginosa PAO1 in complex with NADP+
Descriptor: IMIDAZOLE, L(+)-TARTARIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Popp, M.A, Vit, A, Blankenfeldt, W.
Deposit date:2022-10-16
Release date:2022-11-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:The structure of short-chain dehydrogenase PA3128 from Pseudomonas aeruginosa PAO1
To Be Published
8BRS
DownloadVisualize
BU of 8brs by Molmil
Crystal structure of a variant of penicillin G acylase from Bacillaceae i. s. sp. FJAT-27231 with reduced surface entropy and additionally engineered crystal contact.
Descriptor: (R,R)-2,3-BUTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Wichmann, J, Mayer, J, Mattes, H, Lukat, P, Blankenfeldt, W, Biedendieck, R.
Deposit date:2022-11-23
Release date:2023-05-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Multistep Engineering of a Penicillin G Acylase for Systematic Improvement of Crystallization Efficiency
Cryst.Growth Des., 2023
8BRR
DownloadVisualize
BU of 8brr by Molmil
Crystal structure of a variant of penicillin G acylase from Bacillaceae i. s. sp. FJAT-27231 with reduced surface entropy and additionally engineered crystal contact
Descriptor: (R,R)-2,3-BUTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Wichmann, J, Mayer, J, Mattes, H, Lukat, P, Blankenfeldt, W, Biedendieck, R.
Deposit date:2022-11-23
Release date:2023-05-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Multistep Engineering of a Penicillin G Acylase for Systematic Improvement of Crystallization Efficiency
Cryst.Growth Des., 2023
8BRT
DownloadVisualize
BU of 8brt by Molmil
Crystal structure of a variant of penicillin G acylase from Bacillaceae i. s. sp. FJAT-27231 with reduced surface entropy and additionally engineered crystal contact
Descriptor: (R,R)-2,3-BUTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Wichmann, J, Mayer, J, Mattes, H, Lukat, P, Blankenfeldt, W, Biedendieck, R.
Deposit date:2022-11-23
Release date:2023-05-03
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Multistep Engineering of a Penicillin G Acylase for Systematic Improvement of Crystallization Efficiency
Cryst.Growth Des., 2023
8BTJ
DownloadVisualize
BU of 8btj by Molmil
Murine cytomegalovirus protein M35
Descriptor: (R,R)-2,3-BUTANEDIOL, MALONATE ION, Protein M35
Authors:Schmelz, S, Van den Heuvel, J, Blankenfeldt, W.
Deposit date:2022-11-29
Release date:2023-10-11
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The Cytomegalovirus M35 Protein Directly Binds to the Interferon-beta Enhancer and Modulates Transcription of Ifnb1 and Other IRF3-Driven Genes.
J.Virol., 97, 2023
5IWE
DownloadVisualize
BU of 5iwe by Molmil
E45Q mutant of phenazine biosynthesis protein PhzF in complex with (5R,6R)-6-azaniumyl-5-ethoxycyclohexa-1,3-diene-1-carboxylate
Descriptor: (5R,6R)-6-azaniumyl-5-ethoxycyclohexa-1,3-diene-1-carboxylate, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Diederich, C, Blankenfeldt, W.
Deposit date:2016-03-22
Release date:2017-03-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Mechanisms and Specificity of Phenazine Biosynthesis Protein PhzF.
Sci Rep, 7, 2017
6YZE
DownloadVisualize
BU of 6yze by Molmil
Zinc metalloprotease ProA from native source
Descriptor: ZINC ION, Zinc metalloproteinase
Authors:Schmelz, S, Blankenfeldt, W.
Deposit date:2020-05-06
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Zinc metalloprotease ProA of Legionella pneumophila increases alveolar septal thickness in human lung tissue explants by collagen IV degradation.
Cell.Microbiol., 23, 2021
6ZDT
DownloadVisualize
BU of 6zdt by Molmil
Crystal structure of eukaryotic Fibrillarin with Nop56 N-terminal domain
Descriptor: Nucleolar protein 56, rRNA 2'-O-methyltransferase fibrillarin
Authors:Hoefler, S, Lukat, P, Carlomagno, T, Blankenfeldt, W.
Deposit date:2020-06-15
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:High-resolution structure of eukaryotic Fibrillarin interacting with Nop56 amino-terminal domain.
Rna, 27, 2021
6Q7U
DownloadVisualize
BU of 6q7u by Molmil
Crystal structure of PqsR (MvfR) ligand-binding domain in complex with HHQ
Descriptor: 2-heptyl-1~{H}-quinolin-4-one, Transcriptional regulator MvfR
Authors:Witzgall, F, Xu, N, Blankenfeldt, W.
Deposit date:2018-12-13
Release date:2019-11-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Flexible Fragment Growing Boosts Potency of Quorum-Sensing Inhibitors against Pseudomonas aeruginosa Virulence.
Chemmedchem, 15, 2020
6Q7W
DownloadVisualize
BU of 6q7w by Molmil
Crystal structure of PqsR (MvfR) ligand-binding domain in complex with compound 20
Descriptor: GLYCEROL, Transcriptional regulator MvfR, ~{N}4-[3-(4-fluorophenyl)propyl]-6-(trifluoromethyl)pyridine-2,4-diamine
Authors:Witzgall, F, Blankenfeldt, W.
Deposit date:2018-12-13
Release date:2019-11-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Flexible Fragment Growing Boosts Potency of Quorum-Sensing Inhibitors against Pseudomonas aeruginosa Virulence.
Chemmedchem, 15, 2020
6Q7V
DownloadVisualize
BU of 6q7v by Molmil
Crystal structure of PqsR (MvfR) ligand-binding domain in complex with compound 11
Descriptor: Transcriptional regulator MvfR, ~{N}4-[(4-fluorophenyl)methyl]-6-(trifluoromethyl)pyridine-2,4-diamine
Authors:Witzgall, F, Blankenfeldt, W.
Deposit date:2018-12-13
Release date:2019-11-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Flexible Fragment Growing Boosts Potency of Quorum-Sensing Inhibitors against Pseudomonas aeruginosa Virulence.
Chemmedchem, 15, 2020
7AL5
DownloadVisualize
BU of 7al5 by Molmil
Crystal structure of the selenomethionine substituted hypothetical protein PA1622 from Pseudomonas aeruginosa PAO1
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Feiler, C.G, Blankenfeldt, W.
Deposit date:2020-10-05
Release date:2020-11-11
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Crystal structure of the selenomethionine substituted hypothetical protein PA1622 from Pseudomonas aeruginosa PAO1
To Be Published
7AL6
DownloadVisualize
BU of 7al6 by Molmil
Crystal structure of the hypothetical protein PA1622 from Pseudomonas aeruginosa PAO1
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Probable hydrolase, ...
Authors:Feiler, C.G, Blankenfeldt, W.
Deposit date:2020-10-05
Release date:2020-10-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the hypothetical protein PA1622 from Pseudomonas aeruginosa PAO1
To Be Published
5OE3
DownloadVisualize
BU of 5oe3 by Molmil
Crystal structure of the N-terminal domain of PqsA in complex with anthraniloyl-AMP (crystal form 1)
Descriptor: 1,2-ETHANEDIOL, 5'-O-[(S)-[(2-aminobenzoyl)oxy](hydroxy)phosphoryl]adenosine, ACETATE ION, ...
Authors:Witzgall, F, Ewert, W, Blankenfeldt, W.
Deposit date:2017-07-07
Release date:2017-09-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Structures of the N-Terminal Domain of PqsA in Complex with Anthraniloyl- and 6-Fluoroanthraniloyl-AMP: Substrate Activation in Pseudomonas Quinolone Signal (PQS) Biosynthesis.
Chembiochem, 18, 2017
6R6U
DownloadVisualize
BU of 6r6u by Molmil
Crystal structure of human cis-aconitate decarboxylase
Descriptor: (R,R)-2,3-BUTANEDIOL, Cis-aconitate decarboxylase, SODIUM ION
Authors:Lukat, P, Chen, F, Saile, K, Buessow, K, Pessler, F, Blankenfeldt, W.
Deposit date:2019-03-28
Release date:2019-09-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.705 Å)
Cite:Crystal structure ofcis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis.
Proc.Natl.Acad.Sci.USA, 116, 2019
6R6T
DownloadVisualize
BU of 6r6t by Molmil
Crystal structure of mouse cis-aconitate decarboxylase
Descriptor: Cis-aconitate decarboxylase
Authors:Lukat, P, Chen, F, Saile, K, Buessow, K, Pessler, F, Blankenfeldt, W.
Deposit date:2019-03-28
Release date:2019-09-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.535 Å)
Cite:Crystal structure ofcis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis.
Proc.Natl.Acad.Sci.USA, 116, 2019

220472

건을2024-05-29부터공개중

PDB statisticsPDBj update infoContact PDBjnumon