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PDB: 81 件

4ZDJ
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Crystal structure of the M. tuberculosis CTP synthase PyrG in complex with two UTP molecules
分子名称: CTP synthase, GLYCEROL, MAGNESIUM ION, ...
著者Bellinzoni, M, Barilone, N, Alzari, P.M.
登録日2015-04-17
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG.
Chem.Biol., 22, 2015
4ZDI
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Crystal structure of the M. tuberculosis CTP synthase PyrG (apo form)
分子名称: CALCIUM ION, CTP synthase
著者Bellinzoni, M, Barilone, N, Alzari, P.M.
登録日2015-04-17
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.52 Å)
主引用文献Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG.
Chem.Biol., 22, 2015
2CDN
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Crystal structure of Mycobacterium tuberculosis adenylate kinase complexed with two molecules of ADP and Mg
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENYLATE KINASE, MAGNESIUM ION
著者Bellinzoni, M, Haouz, A, Grana, M, Munier-Lehmann, H, Alzari, P.M.
登録日2006-01-25
公開日2006-05-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Crystal Structure of Mycobacterium Tuberculosis Adenylate Kinase in Complex with Two Molecules of Adp and Mg2+ Supports an Associative Mechanism for Phosphoryl Transfer.
Protein Sci., 15, 2006
4ZDK
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Crystal structure of the M. tuberculosis CTP synthase PyrG in complex with UTP, AMP-PCP and oxonorleucine
分子名称: 5-OXO-L-NORLEUCINE, CTP synthase, MAGNESIUM ION, ...
著者Bellinzoni, M, Barilone, N, Alzari, P.M.
登録日2015-04-17
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG.
Chem.Biol., 22, 2015
2JFS
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BU of 2jfs by Molmil
Crystal structure of the PPM Ser-Thr phosphatase MsPP from Mycobacterium smegmatis in complex with cacodylate
分子名称: CACODYLATE ION, GLYCEROL, MANGANESE (II) ION, ...
著者Bellinzoni, M, Wehenkel, A, Shepard, W, Alzari, P.M.
登録日2007-02-04
公開日2007-07-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Insights Into the Mechanism of Ppm Ser/Thr Phosphatases from the Atomic Resolution Structures of a Mycobacterial Enzyme
Structure, 15, 2007
2JFR
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Crystal structure of the PPM Ser-Thr phosphatase MsPP from Mycobacterium smegmatis in complex with phosphate at 0.83 A resolution
分子名称: CHLORIDE ION, MAGNESIUM ION, MANGANESE (II) ION, ...
著者Bellinzoni, M, Wehenkel, A, Shepard, W, Alzari, P.M.
登録日2007-02-04
公開日2007-07-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (0.83 Å)
主引用文献Insights Into the Mechanism of Ppm Ser/Thr Phosphatases from the Atomic Resolution Structures of a Mycobacterial Enzyme
Structure, 15, 2007
2JFT
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Crystal structure of the PPM Ser-Thr phosphatase MsPP from Mycobacterium smegmatis in complex with sulfate
分子名称: MAGNESIUM ION, MANGANESE (II) ION, SER-THR PHOSPHATASE MSPP, ...
著者Bellinzoni, M, Wehenkel, A, Shepard, W, Alzari, P.M.
登録日2007-02-04
公開日2007-07-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Insights Into the Mechanism of Ppm Ser/Thr Phosphatases from the Atomic Resolution Structures of a Mycobacterial Enzyme
Structure, 15, 2007
4APA
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Crystal structure of Mycobacterium tuberculosis fumarase (Rv1098c) S318A in apo form
分子名称: FUMARATE HYDRATASE CLASS II
著者Bellinzoni, M, Haouz, A, Mechaly, A.E, Alzari, P.M.
登録日2012-03-31
公開日2012-04-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Conformational Changes Upon Ligand Binding in the Essential Class II Fumarase Rv1098C from Mycobacterium Tuberculosis.
FEBS Lett., 586, 2012
4APB
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Crystal structure of Mycobacterium tuberculosis fumarase (Rv1098c) S318C in complex with fumarate
分子名称: CALCIUM ION, FUMARATE HYDRATASE CLASS II, FUMARIC ACID
著者Bellinzoni, M, Haouz, A, Mechaly, A.E, Alzari, P.M.
登録日2012-03-31
公開日2012-04-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Conformational Changes Upon Ligand Binding in the Essential Class II Fumarase Rv1098C from Mycobacterium Tuberculosis.
FEBS Lett., 586, 2012
2WAM
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Crystal structure of Mycobacterium tuberculosis unknown function protein Rv2714
分子名称: CONSERVED HYPOTHETICAL ALANINE AND LEUCINE RICH PROTEIN, GLYCEROL
著者Bellinzoni, M, Grana, M, Buschiazzo, A, Miras, I, Haouz, A, Alzari, P.M.
登録日2009-02-09
公開日2009-10-06
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Mycobacterium Tuberculosis Rv2714, a Representative of a Duplicated Gene Family in Actinobacteria.
Acta Crystallogr.,Sect.F, 65, 2009
4PMR
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Crystal structure of the Mycobacterium tuberculosis Tat-secreted protein Rv2525c in complex with HEPES (monoclinic crystal form II)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SODIUM ION, Tat-secreted protein Rv2525c
著者Bellinzoni, M, Haouz, A, Shepard, W, Alzari, P.M.
登録日2014-05-22
公開日2014-10-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c.
J.Struct.Biol., 188, 2014
4PMN
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Crystal structure of the Mycobacterium tuberculosis Tat-secreted protein Rv2525c in complex with MES (monoclinic crystal form I)
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, SULFATE ION, ...
著者Bellinzoni, M, Haouz, A, Shepard, W, Alzari, P.M.
登録日2014-05-22
公開日2014-10-08
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c.
J.Struct.Biol., 188, 2014
4PMQ
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Crystal structure of the Mycobacterium tuberculosis Tat-secreted protein Rv2525c in complex with L-tartrate (orthorhombic crystal form)
分子名称: GLYCEROL, L(+)-TARTARIC ACID, Tat-secreted protein Rv2525c
著者Bellinzoni, M, Haouz, A, Shepard, W, Alzari, P.M.
登録日2014-05-22
公開日2014-10-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c.
J.Struct.Biol., 188, 2014
4PMO
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BU of 4pmo by Molmil
Crystal structure of the Mycobacterium tuberculosis Tat-secreted protein Rv2525c, monoclinic crystal form I
分子名称: FORMIC ACID, GLYCEROL, SODIUM ION, ...
著者Bellinzoni, M, Haouz, A, Shepard, W, Alzari, P.M.
登録日2014-05-22
公開日2014-10-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c.
J.Struct.Biol., 188, 2014
2V57
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BU of 2v57 by Molmil
Crystal structure of the TetR-like transcriptional regulator LfrR from Mycobacterium smegmatis in complex with proflavine
分子名称: ISOPROPYL ALCOHOL, PROFLAVIN, SULFATE ION, ...
著者Bellinzoni, M, Buroni, S, Riccardi, G, De Rossi, E, Alzari, P.M.
登録日2008-10-02
公開日2009-10-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Plasticity and Distinct Drug-Binding Modes of Lfrr, a Mycobacterial Efflux Pump Regulator.
J.Bacteriol., 191, 2009
2X2B
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BU of 2x2b by Molmil
Crystal structure of malonyl-ACP (acyl carrier protein) from Bacillus subtilis
分子名称: 3-{[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-3-oxopropanoic acid, ACYL CARRIER PROTEIN, PLATINUM (II) ION
著者Bellinzoni, M, Martinez, M.A, DeMendoza, D, Alzari, P.M.
登録日2010-01-12
公開日2010-03-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献A Novel Role of Malonyl-Acp in Lipid Homeostasis.
Biochemistry, 49, 2010
2WGB
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Crystal structure of the TetR-like transcriptional regulator LfrR from Mycobacterium smegmatis
分子名称: SULFATE ION, TETR FAMILY TRANSCRIPTIONAL REPRESSOR LFRR
著者Bellinzoni, M, Buroni, S, Riccardi, G, De Rossi, E, Alzari, P.M.
登録日2009-04-16
公開日2009-10-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Plasticity and Distinct Drug-Binding Modes of Lfrr, a Mycobacterial Efflux Pump Regulator.
J.Bacteriol., 191, 2009
2WZV
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Crystal structure of the FMN-dependent nitroreductase NfnB from Mycobacterium smegmatis
分子名称: FLAVIN MONONUCLEOTIDE, GLYCEROL, NFNB PROTEIN, ...
著者Bellinzoni, M, Manina, G, Riccardi, G, Alzari, P.M.
登録日2009-12-03
公開日2010-07-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Biological and Structural Characterization of the Mycobacterium Smegmatis Nitroreductase Nfnb, and its Role in Benzothiazinone Resistance
Mol.Microbiol., 77, 2010
2Y7E
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BU of 2y7e by Molmil
Crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme (Kce) from Candidatus Cloacamonas acidaminovorans (tetragonal form)
分子名称: 3-KETO-5-AMINOHEXANOATE CLEAVAGE ENZYME, FORMIC ACID, MAGNESIUM ION, ...
著者Bellinzoni, M, Alzari, P.M.
登録日2011-01-31
公開日2011-06-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献3-Keto-5-Aminohexanoate Cleavage Enzyme: A Common Fold for an Uncommon Claisen-Type Condensation.
J.Biol.Chem., 286, 2011
2Y7G
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Crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme (Kce) from C. Cloacamonas acidaminovorans in complex with the product acetoacetate
分子名称: 3-KETO-5-AMINOHEXANOATE CLEAVAGE ENZYME, ACETOACETIC ACID, GLYCEROL, ...
著者Bellinzoni, M, Alzari, P.M.
登録日2011-01-31
公開日2011-06-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献3-Keto-5-Aminohexanoate Cleavage Enzyme: A Common Fold for an Uncommon Claisen-Type Condensation.
J.Biol.Chem., 286, 2011
2Y7D
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Crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme (Kce) from Candidatus Cloacamonas acidaminovorans (orthorombic form)
分子名称: 3-KETO-5-AMINOHEXANOATE CLEAVAGE ENZYME, GLYCEROL, ZINC ION
著者Bellinzoni, M, Alzari, P.M.
登録日2011-01-31
公開日2011-06-01
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献3-Keto-5-Aminohexanoate Cleavage Enzyme: A Common Fold for an Uncommon Claisen-Type Condensation.
J.Biol.Chem., 286, 2011
2XIW
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Crystal structure of the Sac7d-derived IgG1-binder C3-C24S
分子名称: CHLORIDE ION, DNA-BINDING PROTEIN 7D, SULFATE ION
著者Bellinzoni, M, Colinet, S, Behar, G, Alzari, P.M, Pecorari, F.
登録日2010-07-01
公開日2011-07-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Tolerance of the Archaeal Sac7D Scaffold Protein to Alternative Library Designs: Characterization of Anti-Immunoglobulin G Affitins.
Protein Eng.Des.Sel., 26, 2013
2Y7F
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BU of 2y7f by Molmil
Crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme (Kce) from C. Cloacamonas acidaminovorans in complex with the substrate 3- keto-5-aminohexanoate
分子名称: (5S)-5-AMINO-3-OXO-HEXANOIC ACID, 3-KETO-5-AMINOHEXANOATE CLEAVAGE ENZYME, MAGNESIUM ION, ...
著者Bellinzoni, M, Alzari, P.M.
登録日2011-01-31
公開日2011-06-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献3-Keto-5-Aminohexanoate Cleavage Enzyme: A Common Fold for an Uncommon Claisen-Type Condensation.
J.Biol.Chem., 286, 2011
2WZW
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Crystal structure of the FMN-dependent nitroreductase NfnB from Mycobacterium smegmatis in complex with NADPH
分子名称: FLAVIN MONONUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NFNB PROTEIN, ...
著者Bellinzoni, M, Manina, G, Riccardi, G, Alzari, P.M.
登録日2009-12-03
公開日2010-07-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Biological and Structural Characterization of the Mycobacterium Smegmatis Nitroreductase Nfnb, and its Role in Benzothiazinone Resistance
Mol.Microbiol., 77, 2010
6Z0F
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Crystal structure of the membrane pseudokinase YukC/EssB from Bacillus subtilis T7SS
分子名称: ESX secretion system protein YukC
著者Tassinari, M, Bellinzoni, M, Alzari, P.M, Fronzes, R, Gubellini, F.
登録日2020-05-08
公開日2021-05-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.553 Å)
主引用文献The Antibacterial Type VII Secretion System of Bacillus subtilis: Structure and Interactions of the Pseudokinase YukC/EssB.
Mbio, 13, 2022

 

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