2WZW

Crystal structure of the FMN-dependent nitroreductase NfnB from Mycobacterium smegmatis in complex with NADPH

Summary for 2WZW

• Entry DOI: 10.2210/pdb2wzw/pdb
• Related: 2WZV
• Descriptor: NFNB PROTEIN, FLAVIN MONONUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total)
• Functional Keywords: nitroreductase, oxidoreductase
• Biological source: MYCOBACTERIUM SMEGMATIS
• Total number of polymer chains: 2
• Total formula weight: 53821.43

Authors

Bellinzoni, M.,Manina, G.,Riccardi, G.,Alzari, P.M. (deposition date: 2009-12-03, release date: 2010-07-14, Last modification date: 2023-12-20)

• Primary citation: Manina, G.,Bellinzoni, M.,Pasca, M.R.,Neres, J.,Milano, A.,Ribeiro, A.L.,Buroni, S.,Skovierova, H.,Dianiskova, P.,Mikusova, K.,Marak, J.,Makarov, V.,Giganti, D.,Haouz, A.,Lucarelli, A.P.,Degiacomi, G.,Piazza, A.,Chiarelli, L.R.,De Rossi, E.,Salina, E.,Cole, S.T.,Alzari, P.M.,Riccardi, G.; Biological and Structural Characterization of the Mycobacterium Smegmatis Nitroreductase Nfnb, and its Role in Benzothiazinone Resistance; Mol.Microbiol., 77:1172-, 2010; PubMed: 20624223; DOI: 10.1111/J.1365-2958.2010.07277.X

Experimental method

X-RAY DIFFRACTION (1.8 Å)