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PDB: 58 件

5CI9
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Crystal structure of human Tob in complex with inhibitor fragment 6
分子名称: 1-(propan-2-yl)-1H-benzimidazole-5-carboxylic acid, Protein Tob1, SODIUM ION
著者Bai, Y, Tashiro, S, Nagatoishi, S, Suzuki, T, Tsumoto, K, Bartlam, M, Yamamoto, T.
登録日2015-07-11
公開日2015-11-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach
Protein Cell, 6, 2015
5CI8
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Crystal structure of human Tob in complex with inhibitor fragment 1
分子名称: Protein Tob1, pyrrolo[1,2-a]quinoxalin-4(5H)-one
著者Bai, Y, Tashiro, S, Nagatoishi, S, Suzuki, T, Tsumoto, K, Bartlam, M, Yamamoto, T.
登録日2015-07-11
公開日2015-11-18
最終更新日2015-12-09
実験手法X-RAY DIFFRACTION (2.328 Å)
主引用文献Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach
Protein Cell, 6, 2015
6UZ8
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Cryo-EM structure of human TRPC6 in complex with agonist AM-0883
分子名称: (5-chloro-1'H-spiro[indole-3,4'-piperidin]-1'-yl)[(2R)-2,3-dihydro-1,4-benzodioxin-2-yl]methanone, 2-[[(2~{S})-2-decanoyloxy-3-dodecanoyloxy-propoxy]-oxidanyl-phosphoryl]oxyethyl-trimethyl-azanium, CHOLESTEROL HEMISUCCINATE, ...
著者Bai, Y, Yu, X, Huang, X, Chen, H.
登録日2019-11-14
公開日2020-03-18
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Structural basis for pharmacological modulation of the TRPC6 channel.
Elife, 9, 2020
6UZA
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BU of 6uza by Molmil
Cryo-EM structure of human TRPC6 in complex with antagonist AM-1473
分子名称: 2-[[(2~{S})-2-decanoyloxypropoxy]-oxidanyl-phosphoryl]oxyethyl-trimethyl-azanium, 4-({(1R,2R)-2-[(3R)-3-aminopiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl}oxy)benzonitrile, CHOLESTEROL HEMISUCCINATE, ...
著者Bai, Y, Yu, X, Huang, X, Chen, H.
登録日2019-11-14
公開日2020-03-18
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Structural basis for pharmacological modulation of the TRPC6 channel.
Elife, 9, 2020
4YMK
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BU of 4ymk by Molmil
Crystal Structure of Stearoyl-Coenzyme A Desaturase 1
分子名称: Acyl-CoA desaturase 1, STEAROYL-COENZYME A, ZINC ION, ...
著者Bai, Y, McCoy, J.G, Rajashankar, K.R, Zhou, M.
登録日2015-03-06
公開日2015-06-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.605 Å)
主引用文献X-ray structure of a mammalian stearoyl-CoA desaturase.
Nature, 524, 2015
2MIA
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BU of 2mia by Molmil
Solution structure of allatide C4, conformation 2
分子名称: alpha amylase inhibitor
著者Bai, Y, Pervushin, K.
登録日2013-12-12
公開日2015-01-14
最終更新日2015-03-25
実験手法SOLUTION NMR
主引用文献Allotides: Proline-rich Cystine Knot alpha-Amylase Inhibitors from the Allamanda cathartica
To be Published
2K8F
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BU of 2k8f by Molmil
Structural Basis for the Regulation of p53 Function by p300
分子名称: Cellular tumor antigen p53, Histone acetyltransferase p300
著者Bai, Y, Feng, H, Jenkins, L.M, Durell, S.R, Wiodawer, A, Appella, E.
登録日2008-09-08
公開日2009-03-03
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Structural Basis for p300 Taz2-p53 TAD1 Binding and Modulation by Phosphorylation.
Structure, 17, 2009
2OOE
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BU of 2ooe by Molmil
Crystal structure of HAT domain of murine CstF-77
分子名称: Cleavage stimulation factor 77 kDa subunit
著者Bai, Y, Auperin, T.C, Chou, C.-Y, Chang, G.-G, Manley, J.L, Tong, L.
登録日2007-01-25
公開日2007-04-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of Murine CstF-77: Dimeric Association and Implications for Polyadenylation of mRNA Precursors.
Mol.Cell, 25, 2007
2OND
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Crystal Structure of the HAT-C domain of murine CstF-77
分子名称: Cleavage stimulation factor 77 kDa subunit
著者Bai, Y, Auperin, T.C, Chou, C.-Y, Chang, G.-G, Manley, J.L, Tong, L.
登録日2007-01-23
公開日2007-04-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Murine CstF-77: Dimeric Association and Implications for Polyadenylation of mRNA Precursors.
Mol.Cell, 25, 2007
2MI9
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Solution structure of allatide C4, conformation 1
分子名称: alpha amylase inhibitor
著者Bai, Y, Pervushin, K.
登録日2013-12-12
公開日2015-01-14
最終更新日2015-03-25
実験手法SOLUTION NMR
主引用文献Allotides: Proline-rich Cystine Knot alpha-Amylase Inhibitors from the Allamanda cathartica
To be Published
3PQ1
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Crystal structure of human mitochondrial poly(A) polymerase (PAPD1)
分子名称: Poly(A) RNA polymerase
著者Bai, Y, Srivastava, S.K, Chang, J.H, Tong, L.
登録日2010-11-25
公開日2011-03-30
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for dimerization and activity of human PAPD1, a noncanonical poly(A) polymerase.
Mol.Cell, 41, 2011
3EJ5
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complex of Ricin A chain and pyrimidine-based inhibitor
分子名称: 4-[3-(2-amino-4-hydroxy-6-oxo-1,6-dihydropyrimidin-5-yl)propyl]benzoic acid, Ricin A chain
著者Bai, Y, Monzingo, A.F, Robertus, J.D.
登録日2008-09-17
公開日2009-04-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The X-ray structure of ricin A chain with a novel inhibitor
Arch.Biochem.Biophys., 483, 2009
1M6T
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BU of 1m6t by Molmil
CRYSTAL STRUCTURE OF B562RIL, A REDESIGNED FOUR HELIX BUNDLE
分子名称: SULFATE ION, Soluble cytochrome b562
著者Chu, R, Takei, J, Knowlton, J.R, Andrykovitch, M, Pei, W, Kajava, A.V, Steinbach, P.J, Ji, X, Bai, Y.
登録日2002-07-17
公開日2002-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Redesign of a Four-Helix Bundle Protein by Phage Display Coupled with Proteolysis and Structural Characterization by NMR and X-ray Crystallography
J.Mol.Biol., 323, 2002
5JBE
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BU of 5jbe by Molmil
4,6-alpha-glucanotransferase GTFB from Lactobacillus reuteri 121 complexed with an isomalto-maltopentasaccharide
分子名称: ACETATE ION, CALCIUM ION, Inactive glucansucrase, ...
著者Pijning, T, Dijkstra, B.W, Bai, Y, Gangoiti-Munecas, J, Dijkhuizen, L.
登録日2016-04-13
公開日2017-01-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of 4,6-alpha-Glucanotransferase Supports Diet-Driven Evolution of GH70 Enzymes from alpha-Amylases in Oral Bacteria.
Structure, 25, 2017
7U0G
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BU of 7u0g by Molmil
structure of LIN28b nucleosome bound 3 OCT4
分子名称: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Lian, T, Guan, R, Bai, Y.
登録日2022-02-18
公開日2023-06-28
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
7U0I
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Structure of LIN28b nucleosome bound 2 OCT4
分子名称: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Tengfei, L, Guan, R, Bai, Y.
登録日2022-02-18
公開日2023-06-28
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
7U0J
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Structure of 162bp LIN28b nucleosome
分子名称: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Lian, T, Guan, R, Bai, Y.
登録日2022-02-18
公開日2023-06-28
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
2JSS
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BU of 2jss by Molmil
NMR structure of chaperone Chz1 complexed with histone H2A.Z-H2B
分子名称: Chimera of Histone H2B.1 and Histone H2A.Z, Uncharacterized protein YER030W
著者Zhou, Z, Feng, H, Hansen, D.F, Kato, H, Luk, E, Freedberg, D.I, Kay, L.E, Wu, C, Bai, Y.
登録日2007-07-11
公開日2008-05-20
最終更新日2021-08-18
実験手法SOLUTION NMR
主引用文献NMR structure of chaperone Chz1 complexed with histones H2A.Z-H2B.
Nat.Struct.Mol.Biol., 15, 2008
4TQ5
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BU of 4tq5 by Molmil
Structure of a UbiA homolog from Archaeoglobus fulgidus
分子名称: octyl beta-D-glucopyranoside, prenyltransferase
著者Huang, H, Levin, E.J, Bai, Y, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2014-06-10
公開日2014-07-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.2023 Å)
主引用文献Structure of a Membrane-Embedded Prenyltransferase Homologous to UBIAD1.
Plos Biol., 12, 2014
4TQ6
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Structure of a UbiA homolog from Archaeoglobus fulgidus bound to Cd2+
分子名称: CADMIUM ION, prenyltransferase
著者Huang, H, Levin, E.J, Bai, Y, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2014-06-10
公開日2014-07-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.0678 Å)
主引用文献Structure of a Membrane-Embedded Prenyltransferase Homologous to UBIAD1.
Plos Biol., 12, 2014
4TQ4
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Structure of a UbiA homolog from Archaeoglobus fulgidus bound to DMAPP and Mg2+
分子名称: DIMETHYLALLYL DIPHOSPHATE, MAGNESIUM ION, prenyltransferase
著者Huang, H, Levin, E.J, Bai, Y, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2014-06-10
公開日2014-07-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5025 Å)
主引用文献Structure of a Membrane-Embedded Prenyltransferase Homologous to UBIAD1.
Plos Biol., 12, 2014
4TQ3
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Structure of a UbiA homolog from Archaeoglobus fulgidus bound to GPP and Mg2+
分子名称: GERANYL DIPHOSPHATE, MAGNESIUM ION, Prenyltransferase
著者Huang, H, Levin, E.J, Bai, Y, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2014-06-10
公開日2014-07-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4076 Å)
主引用文献Structure of a Membrane-Embedded Prenyltransferase Homologous to UBIAD1.
Plos Biol., 12, 2014
8SPS
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High resolution structure of ESRRB nucleosome bound OCT4 at site a and site b
分子名称: DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Lian, T, Guan, R, Bai, Y.
登録日2023-05-03
公開日2023-06-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
8SPU
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Structure of ESRRB nucleosome bound OCT4 at site c
分子名称: DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Lian, T, Guan, R, Bai, Y.
登録日2023-05-03
公開日2023-06-28
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
8SYP
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Genomic CX3CR1 nucleosome
分子名称: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Lian, T, Guan, R, Bai, Y.
登録日2023-05-25
公開日2023-11-01
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha.
Nat.Struct.Mol.Biol., 31, 2024

 

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