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PDB: 1208 results

1ZS2
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BU of 1zs2 by Molmil
Amylosucrase Mutant E328Q in a ternary complex with sucrose and maltoheptaose
Descriptor: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, amylosucrase, ...
Authors:Skov, L.K, Mirza, O, Sprogoe, D, van der Veen, B.A, Remaud-Simeon, M, Albenne, C, Monsan, P, Gajhede, M.
Deposit date:2005-05-23
Release date:2006-05-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Crystal structure of the Glu328Gln mutant of Neisseria polysaccharea amylosucrase in complex with sucrose and maltoheptaose
BIOCATAL.BIOTRANSFOR., 24, 2006
8EBL
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BU of 8ebl by Molmil
Structure of KLHDC2 substrate binding domain bound to C-degron from EPHB2
Descriptor: GLU-ASP-SER-HIS-LYS-GLU-SER-ASN-ASP-CYS-SER-CYS-GLY-GLY, Kelch domain-containing protein 2
Authors:Scott, D.C, Schulman, B.A.
Deposit date:2022-08-31
Release date:2023-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity.
Mol.Cell, 83, 2023
5J54
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BU of 5j54 by Molmil
The Structure and Mechanism of NOV1, a Resveratrol-Cleaving Dioxygenase
Descriptor: Carotenoid oxygenase, FE (III) ION, OXYGEN MOLECULE, ...
Authors:McAndrew, R.P, Pereira, J.H, Sathitsuksanoh, N, Sale, K.L, Simmons, B.A, Adams, P.D.
Deposit date:2016-04-01
Release date:2016-11-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structure and mechanism of NOV1, a resveratrol-cleaving dioxygenase.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
1ZZA
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BU of 1zza by Molmil
Solution NMR Structure of the Membrane Protein Stannin
Descriptor: Stannin
Authors:Buck-Koehntop, B.A, Mascioni, A, Buffy, J.J, Veglia, G.
Deposit date:2005-06-13
Release date:2005-12-20
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure, dynamics, and membrane topology of stannin: a mediator of neuronal cell apoptosis induced by trimethyltin chloride.
J.Mol.Biol., 354, 2005
8E84
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BU of 8e84 by Molmil
Human PCNA mutant- C148S
Descriptor: Proliferating cell nuclear antigen
Authors:Magrino, J, Page, B, Gaubitz, C, Kelch, B.A.
Deposit date:2022-08-25
Release date:2023-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A thermosensitive PCNA allele underlies an ataxia-telangiectasia-like disorder.
J.Biol.Chem., 299, 2023
7A8Y
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BU of 7a8y by Molmil
X-ray crystal structure of Aspartate alpha-decarboxylase in complex with D-Serine
Descriptor: 1,2-ETHANEDIOL, Aspartate 1-decarboxylase, D-SERINE, ...
Authors:Yorke, B.A, Raskar, T.
Deposit date:2020-08-31
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure and diffusive dynamics of aspartate alpha-decarboxylase (ADC) liganded with D-serine in aqueous solution.
Phys Chem Chem Phys, 2022
1YI9
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BU of 1yi9 by Molmil
Crystal Structure Analysis of the oxidized form of the M314I mutant of Peptidylglycine alpha-Hydroxylating Monooxygenase
Descriptor: COPPER (II) ION, GLYCEROL, Peptidyl-glycine alpha-amidating monooxygenase
Authors:Siebert, X, Eipper, B.A, Mains, R.E, Prigge, S.T, Blackburn, N.J, Amzel, L.M.
Deposit date:2005-01-11
Release date:2005-11-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The catalytic copper of Peptidylglycine alpha-Hydroxylating Monooxygenase also plays a critical structural role.
Biophys.J., 89, 2005
5J53
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BU of 5j53 by Molmil
The Structure and Mechanism of NOV1, a Resveratrol-Cleaving Dioxygenase
Descriptor: Carotenoid oxygenase, FE (III) ION, OXYGEN MOLECULE, ...
Authors:McAndrew, R.P, Pereira, J.H, Sathitsuksanoh, N, Sale, K.L, Simmons, B.A, Adams, P.D.
Deposit date:2016-04-01
Release date:2016-11-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Structure and mechanism of NOV1, a resveratrol-cleaving dioxygenase.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
8E7I
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BU of 8e7i by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR P24S amyloidosis patient
Descriptor: Transthyretin protein
Authors:Nguyen, B.A, Saelices, L.
Deposit date:2022-08-24
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Cardiac amyloid fibrils extracted from a variant ATTR P24S amyloidosis patient
To Be Published
8E7H
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BU of 8e7h by Molmil
Cryo-EM structure of cardiac amyloid fibril from a wild-type amyloidosis patient
Descriptor: Transthyretin
Authors:Nguyen, B.A, Saelices, L.
Deposit date:2022-08-23
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
To Be Published
8E7E
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BU of 8e7e by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient
Descriptor: Transthyretin
Authors:Nguyen, B.A, Singh, V, Afrin, S, Saelices, L.
Deposit date:2022-08-23
Release date:2023-08-30
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nat Commun, 15, 2024
8E7J
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BU of 8e7j by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient
Descriptor: Transthyretin
Authors:Nguyen, B.A, Saelices, L.
Deposit date:2022-08-24
Release date:2023-08-30
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nat Commun, 15, 2024
8E7D
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BU of 8e7d by Molmil
Cryo-EM structure of wild-type transthyretin amyloid from heart tissue
Descriptor: Transthyretin
Authors:Nguyen, B.A, Saelices, L.
Deposit date:2022-08-23
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
To Be Published
7ADP
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BU of 7adp by Molmil
Cryo-EM structure of human ER membrane protein complex in GDN detergent
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ER membrane protein complex subunit 1, ER membrane protein complex subunit 10, ...
Authors:Braeuning, B, Prabu, J.R, Miller-Vedam, L.E, Weissman, J.S, Frost, A, Schulman, B.A.
Deposit date:2020-09-15
Release date:2020-12-02
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.
Elife, 9, 2020
2A43
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BU of 2a43 by Molmil
Crystal Structure of a Luteoviral RNA Pseudoknot and Model for a Minimal Ribosomal Frameshifting Motif
Descriptor: MAGNESIUM ION, RNA Pseudoknot
Authors:Pallan, P.S, Marshall, W.S, Harp, J, Jewett III, F.C, Wawrzak, Z, Brown II, B.A, Rich, A, Egli, M.
Deposit date:2005-06-27
Release date:2005-09-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Crystal Structure of a Luteoviral RNA Pseudoknot and Model for a Minimal Ribosomal Frameshifting Motif
Biochemistry, 44, 2005
5HPS
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BU of 5hps by Molmil
System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: WWP1 and UbV P1.1
Descriptor: Ubiquitin variant P1.1, WWP1 HECT
Authors:Wu, K.-P, Mercredi, P.Y, Schulman, B.A.
Deposit date:2016-01-20
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
2AST
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BU of 2ast by Molmil
Crystal structure of Skp1-Skp2-Cks1 in complex with a p27 peptide
Descriptor: BENZAMIDINE, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ...
Authors:Hao, B, Zhang, N, Schulman, B.A, Wu, G, Pagano, M, Pavletich, N.P.
Deposit date:2005-08-24
Release date:2005-10-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of the Cks1-Dependent Recognition of p27(Kip1) by the SCF(Skp2) Ubiquitin Ligase.
Mol.Cell, 20, 2005
5JG6
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BU of 5jg6 by Molmil
APC11-Ubv shows role of noncovalent RING-Ubiquitin interactions in processive multiubiquitination and Ubiquitin chain elongation by APC/C
Descriptor: Anaphase-promoting complex subunit 11, Polyubiquitin-B, ZINC ION
Authors:Brown, N.G, Zhang, W, Yu, S, Miller, D.J, Sidhu, S.S, Schulman, B.A.
Deposit date:2016-04-19
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.0013 Å)
Cite:Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell, 165, 2016
2B4E
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BU of 2b4e by Molmil
Crystal Structure of Murine Coronin-1: monoclinic form
Descriptor: Coronin-1A
Authors:Appleton, B.A, Wu, P, Wiesmann, C.
Deposit date:2005-09-23
Release date:2005-12-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of murine coronin-1: a regulator of actin cytoskeletal dynamics in lymphocytes
Structure, 14, 2006
6YZ2
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BU of 6yz2 by Molmil
Full length Open-form Sodium Channel NavMs F208L
Descriptor: DODECAETHYLENE GLYCOL, HEGA-10, Ion transport protein, ...
Authors:Sula, A, Sait, L.G, Hollingworth, D, Wallace, B.A.
Deposit date:2020-05-06
Release date:2020-11-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Cannabidiol interactions with voltage-gated sodium channels.
Elife, 9, 2020
6Z8C
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BU of 6z8c by Molmil
Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with N-desmethyltamoxifen (3.2 A resolution)
Descriptor: 2-[4-[(~{Z})-1,2-diphenylbut-1-enyl]phenoxy]-~{N}-methyl-ethanamine, DODECAETHYLENE GLYCOL, HEGA-10, ...
Authors:Sula, A, Hollingworth, D, Wallace, B.A.
Deposit date:2020-06-02
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A tamoxifen receptor within a voltage-gated sodium channel.
Mol.Cell, 81, 2021
2B7D
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BU of 2b7d by Molmil
Factor VIIa Inhibitors: Chemical Optimization, Preclinical Pharmacokinetics, Pharmacodynamics, and Efficacy in a Baboon Thrombosis Model
Descriptor: (2R)-2-[5-(5-CARBAMIMIDOYL-1H-BENZOIMIDAZOL-2-YL)-6,2'-DIHYDROXY-5'-UREIDOMETHYL-BIPHENYL-3-YL]-SUCCINIC ACID, Coagulation factor VII, Tissue factor
Authors:Young, W.B, Mordenti, J, Torkelson, S, Shrader, W.D, Kolesnikov, A, Rai, R, Liu, L, Hu, H, Leahy, E.M, Green, M.J, Sprengeler, P.A, Katz, B.A, Yu, C, Janc, J.W, Elrod, K.C, Marzec, U.M, Hanson, S.R.
Deposit date:2005-10-04
Release date:2006-02-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Factor VIIa inhibitors: Chemical optimization, preclinical pharmacokinetics, pharmacodynamics, and efficacy in an arterial baboon thrombosis model.
Bioorg.Med.Chem.Lett., 16, 2006
2ANW
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BU of 2anw by Molmil
Expression, crystallization and three-dimensional structure of the catalytic domain of human plasma kallikrein: Implications for structure-based design of protease inhibitors
Descriptor: BENZAMIDINE, plasma kallikrein, light chain
Authors:Tang, J, Yu, C.L, Williams, S.R, Springman, E, Jeffery, D, Sprengeler, P.A, Estevez, A, Sampang, J, Shrader, W, Spencer, J.R, Young, W.B, McGrath, M.E, Katz, B.A.
Deposit date:2005-08-11
Release date:2005-10-11
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Expression, crystallization, and three-dimensional structure of the catalytic domain of human plasma kallikrein.
J.Biol.Chem., 280, 2005
7B5N
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BU of 7b5n by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-UBE2L3~Ub~ARIH1.
Descriptor: 5-azanylpentan-2-one, Cullin-1, E3 ubiquitin-protein ligase ARIH1, ...
Authors:Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
Deposit date:2020-12-05
Release date:2021-02-10
Last modified:2021-03-10
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
7B5R
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BU of 7b5r by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27
Descriptor: Cullin-1, Cyclin-A2, Cyclin-dependent kinase 2, ...
Authors:Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
Deposit date:2020-12-07
Release date:2021-02-10
Last modified:2021-03-10
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021

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