1APQ
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![BU of 1apq by Molmil](/molmil-images/mine/1apq) | STRUCTURE OF THE EGF-LIKE MODULE OF HUMAN C1R, NMR, 19 STRUCTURES | Descriptor: | COMPLEMENT PROTEASE C1R | Authors: | Bersch, B, Hernandez, J.-F, Marion, D, Arlaud, G.J. | Deposit date: | 1997-07-22 | Release date: | 1997-09-17 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Solution structure of the epidermal growth factor (EGF)-like module of human complement protease C1r, an atypical member of the EGF family. Biochemistry, 37, 1998
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1MD7
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![BU of 1md7 by Molmil](/molmil-images/mine/1md7) | Monomeric structure of the zymogen of complement protease C1r | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C1R COMPLEMENT SERINE PROTEASE | Authors: | Budayova-Spano, M, Grabarse, W, Thielens, N.M, Hillen, H, Lacroix, M, Schmidt, M, Fontecilla-Camps, J, Arlaud, G.J, Gaboriaud, C. | Deposit date: | 2002-08-07 | Release date: | 2003-08-07 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism Structure, 10, 2002
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1SZB
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![BU of 1szb by Molmil](/molmil-images/mine/1szb) | Crystal structure of the human MBL-associated protein 19 (MAp19) | Descriptor: | CALCIUM ION, mannose binding lectin-associated serine protease-2 related protein, MAp19 (19kDa) | Authors: | Gregory, L.A, Thielens, N.M, Arlaud, G.J, Fontecilla-Camps, J.C, Gaboriaud, C. | Deposit date: | 2004-04-05 | Release date: | 2004-06-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The X-ray structure of human MBL-associated protein 19 (MAp19) and its interaction site with mannan-binding lectin and L-ficolin J.Biol.Chem., 279, 2004
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3POS
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![BU of 3pos by Molmil](/molmil-images/mine/3pos) | Crystal structure of the globular domain of human calreticulin | Descriptor: | CALCIUM ION, Calreticulin | Authors: | Chouquet, A, Paidassi, H, Ling, W.-L, Frachet, P, Houen, G, Arlaud, G.J, Gaboriaud, C. | Deposit date: | 2010-11-23 | Release date: | 2011-03-09 | Last modified: | 2017-08-09 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | X-ray structure of the human calreticulin globular domain reveals a Peptide-binding area and suggests a multi-molecular mechanism Plos One, 6, 2011
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2WNU
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![BU of 2wnu by Molmil](/molmil-images/mine/2wnu) | Complex between c1q globular heads and heparan sulfate | Descriptor: | 2-O-sulfo-beta-L-altropyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C1Q SUBCOMPONENT SUBUNIT A, ... | Authors: | Garlatti, V, Chouquet, A, Lunardi, T, Thielens, N.M, Arlaud, G.J, Gaboriaud, C. | Deposit date: | 2009-07-20 | Release date: | 2010-05-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Cutting Edge: C1Q Binds Deoxyribose and Heparan Sulfate Through Neighboring Sites of its Recognition Domain. J.Immunol., 185, 2010
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2WNP
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![BU of 2wnp by Molmil](/molmil-images/mine/2wnp) | M-ficolin mutant Y271F | Descriptor: | CALCIUM ION, FICOLIN-1, ISOPROPYL ALCOHOL | Authors: | Gout, E, Garlatti, V, Smith, D.F, Lacroix, M, Dumestre-Perard, C, Lunardi, T, Arlaud, G.J, Gaboriaud, C, Thielens, N.M. | Deposit date: | 2009-07-16 | Release date: | 2009-12-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | Carbohydrate Recognition Properties of Human Ficolins: Glycan Array Screening Reveals the Sialic Acid Binding Specificity of M-Ficolin. J.Biol.Chem., 285, 2010
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2WNV
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![BU of 2wnv by Molmil](/molmil-images/mine/2wnv) | Complex between C1q globular heads and deoxyribose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-beta-D-erythro-pentofuranose, CALCIUM ION, ... | Authors: | Garlatti, V, Chouquet, A, Lunardi, T, Thielens, N.M, Arlaud, G.J, Gaboriaud, C. | Deposit date: | 2009-07-20 | Release date: | 2010-05-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Cutting Edge: C1Q Binds Deoxyribose and Heparan Sulfate Through Neighboring Sites of its Recognition Domain. J.Immunol., 185, 2010
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1PK6
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![BU of 1pk6 by Molmil](/molmil-images/mine/1pk6) | Globular Head of the Complement System Protein C1q | Descriptor: | CALCIUM ION, Complement C1q subcomponent, A chain precursor, ... | Authors: | Gaboriaud, C, Juanhuix, J, Gruez, A, Lacroix, M, Darnault, C, Pignol, D, Verger, D, Fontecilla-Camps, J.C, Arlaud, G.J. | Deposit date: | 2003-06-05 | Release date: | 2003-10-21 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The crystal structure of the globular head of complement protein C1q provides a basis for its versatile recognition properties. J.Biol.Chem., 278, 2003
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1NZI
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![BU of 1nzi by Molmil](/molmil-images/mine/1nzi) | Crystal Structure of the CUB1-EGF Interaction Domain of Complement Protease C1s | Descriptor: | CALCIUM ION, Complement C1s component, MAGNESIUM ION | Authors: | Gregory, L.A, Thielens, N.M, Arlaud, G.J, Fontecilla-Camps, J.C, Gaboriaud, C. | Deposit date: | 2003-02-18 | Release date: | 2003-06-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | X-ray structure of the Ca2+-binding interaction domain of C1s. Insights into the assembly of the C1 complex of complement J.Biol.Chem., 278, 2003
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1MD8
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![BU of 1md8 by Molmil](/molmil-images/mine/1md8) | Monomeric structure of the active catalytic domain of complement protease C1r | Descriptor: | C1R COMPLEMENT SERINE PROTEASE | Authors: | Budayova-Spano, M, Grabarse, W, Thielens, N.M, Hillen, H, Lacroix, M, Schmidt, M, Fontecilla-Camps, J, Arlaud, G.J, Gaboriaud, C. | Deposit date: | 2002-08-07 | Release date: | 2003-08-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism Structure, 10, 2002
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2JHH
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![BU of 2jhh by Molmil](/molmil-images/mine/2jhh) | Structure of globular heads of M-ficolin at acidic pH | Descriptor: | CALCIUM ION, FICOLIN-1 | Authors: | Garlatti, V, Martin, L, Gout, E, Reiser, J.B, Arlaud, G.J, Thielens, N.M, Gaboriaud, C. | Deposit date: | 2007-02-22 | Release date: | 2007-10-09 | Last modified: | 2019-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for innate immune sensing by M-ficolin and its control by a pH-dependent conformational switch. J. Biol. Chem., 282, 2007
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2JHK
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![BU of 2jhk by Molmil](/molmil-images/mine/2jhk) | Structure of globular heads of M-ficolin complexed with N-acetyl-D- glucosamine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FICOLIN-1 | Authors: | Garlatti, V, Martin, L, Gout, E, Reiser, J.B, Arlaud, G.J, Thielens, N.M, Gaboriaud, C. | Deposit date: | 2007-02-22 | Release date: | 2007-10-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch. J.Biol.Chem., 282, 2007
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2JHI
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![BU of 2jhi by Molmil](/molmil-images/mine/2jhi) | Structure of globular heads of M-ficolin complexed with N-acetyl-D- galactosamine | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, CALCIUM ION, FICOLIN-1 | Authors: | Garlatti, V, Martin, L, Gout, E, Reiser, J.B, Arlaud, G.J, Thielens, N.M, Gaboriaud, C. | Deposit date: | 2007-02-22 | Release date: | 2007-10-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch. J.Biol.Chem., 282, 2007
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2JHL
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![BU of 2jhl by Molmil](/molmil-images/mine/2jhl) | Structure of globular heads of M-ficolin complexed with sialic acid | Descriptor: | CALCIUM ION, FICOLIN-1, N-acetyl-beta-neuraminic acid | Authors: | Garlatti, V, Martin, L, Gout, E, Reiser, J.B, Arlaud, G.J, Thielens, N.M, Gaboriaud, C. | Deposit date: | 2007-02-22 | Release date: | 2007-10-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch. J.Biol.Chem., 282, 2007
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2JHM
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![BU of 2jhm by Molmil](/molmil-images/mine/2jhm) | Structure of globular heads of M-ficolin at neutral pH | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, FICOLIN-1, ... | Authors: | Garlatti, V, Martin, L, Gout, E, Reiser, J.B, Arlaud, G.J, Thielens, N.M, Gaboriaud, C. | Deposit date: | 2007-02-22 | Release date: | 2007-10-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch. J.Biol.Chem., 282, 2007
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2JG8
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![BU of 2jg8 by Molmil](/molmil-images/mine/2jg8) | Crystallographic structure of human C1q globular heads complexed to phosphatidyl-serine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C1q subcomponent subunit A, ... | Authors: | Paidassi, H, Tacnet-Delorme, P, Garlatti, V, Darnault, C, Ghebrehiwet, B, Gaboriaud, C, Arlaud, G.J, Frachet, P. | Deposit date: | 2007-02-09 | Release date: | 2008-02-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | C1Q Binds Phosphatidylserine and Likely Acts as a Multiligand-Bridging Molecule in Apoptotic Cell Recognition. J.Immunol., 180, 2008
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2JG9
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![BU of 2jg9 by Molmil](/molmil-images/mine/2jg9) | Crystallographic structure of human C1q globular heads (P1) | Descriptor: | CALCIUM ION, Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, ... | Authors: | Paidassi, H, Tacnet-Delorme, P, Garlatti, V, Darnault, C, Ghebrehiwet, B, Gaboriaud, C, Arlaud, G.J, Frachet, P. | Deposit date: | 2007-02-09 | Release date: | 2008-02-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | C1Q Binds Phosphatidylserine and Likely Acts as a Multiligand-Bridging Molecule in Apoptotic Cell Recognition. J.Immunol., 180, 2008
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