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PDB: 49 件

6K3A
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Crystal structure of human PCNA in complex with DNMT1 PIP box motif.
分子名称: Peptide from DNA (cytosine-5)-methyltransferase 1, Proliferating cell nuclear antigen
著者Jimenji, T, Kori, S, Arita, K.
登録日2019-05-17
公開日2019-06-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of PCNA in complex with DNMT1 PIP box reveals the basis for the molecular mechanism of the interaction.
Biochem.Biophys.Res.Commun., 516, 2019
3WO4
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Crystal structure of the IL-18 signaling ternary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H.
登録日2013-12-19
公開日2014-12-17
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The structural basis for receptor recognition of human interleukin-18
Nat Commun, 5, 2014
3WO2
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Crystal structure of human interleukin-18
分子名称: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Interleukin-18, SULFATE ION
著者Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H.
登録日2013-12-19
公開日2014-12-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献The structural basis for receptor recognition of human interleukin-18
Nat Commun, 5, 2014
3WO3
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Crystal structure of IL-18 in complex with IL-18 receptor alpha
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H.
登録日2013-12-19
公開日2014-12-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The structural basis for receptor recognition of human interleukin-18
Nat Commun, 5, 2014
2CT9
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The crystal structure of calcineurin B homologous proein 1 (CHP1)
分子名称: CALCIUM ION, Calcium-binding protein p22
著者Naoe, Y, Arita, K, Hashimoto, H, Kanazawa, H, Sato, M, Shimizu, T.
登録日2005-05-23
公開日2005-07-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural characterization of calcineurin B homologous protein 1
J.Biol.Chem., 280, 2005
2DW5
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Crystal structure of human peptidylarginine deiminase 4 in complex with N-alpha-benzoyl-N5-(2-fluoro-1-iminoethyl)-L-ornithine amide
分子名称: CALCIUM ION, N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE, Protein-arginine deiminase type-4, ...
著者Luo, Y, Arita, K, Sato, M, Thompson, P.R.
登録日2006-08-04
公開日2006-10-17
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Inhibitors and Inactivators of Protein Arginine Deiminase 4: Functional and Structural Characterization
Biochemistry, 45, 2006
3B0F
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Crystal structure of the UBA domain of p62 and its interaction with ubiquitin
分子名称: SULFATE ION, Sequestosome-1
著者Isogai, S, Morimoto, D, Arita, K, Unzai, S, Tenno, T, Hasegawa, J, Sou, Y, Komatsu, M, Tanaka, K, Shirakawa, M, Tochio, H.
登録日2011-06-09
公開日2011-06-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of the ubiquitin-associated (UBA) domain of p62 and its interaction with ubiquitin.
J.Biol.Chem., 286, 2011
3A4S
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The crystal structure of the SLD2:Ubc9 complex
分子名称: NFATC2-interacting protein, SUMO-conjugating enzyme UBC9
著者Sekiyama, N, Arita, K, Ikeda, Y, Ariyoshi, M, Tochio, H, Saitoh, H, Shirakawa, M.
登録日2009-07-14
公開日2010-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for regulation of poly-SUMO chain by a SUMO-like domain of Nip45
Proteins, 78, 2009
3A4R
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The crystal structure of SUMO-like domain 2 in Nip45
分子名称: 1,2-ETHANEDIOL, NFATC2-interacting protein, SULFATE ION
著者Sekiyama, N, Arita, K, Ikeda, Y, Ariyoshi, M, Tochio, H, Saitoh, H, Shirakawa, M.
登録日2009-07-14
公開日2010-02-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Structural basis for regulation of poly-SUMO chain by a SUMO-like domain of Nip45
Proteins, 78, 2009
3VYB
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Crystal structure of methyl CpG binding domain of MBD4 in complex with the 5mCG/hmCG sequence
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(*GP*TP*CP*(5HC)P*GP*GP*TP*AP*GP*TP*GP*AP*CP*T)-3'), ...
著者Otani, J, Arita, K, Kato, T, Kinoshita, M, Ariyoshi, M, Shirakawa, M.
登録日2012-09-22
公開日2013-01-16
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4
J.Biol.Chem., 288, 2013
3VXX
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Crystal structure of methyl CpG binding domain of MBD4 in complex with the 5mCG/5mCG sequence
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(*GP*TP*CP*(5CM)P*GP*GP*TP*AP*GP*TP*GP*AP*CP*T)-3'), ...
著者Otani, J, Arita, K, Kato, T, Kinoshita, M, Ariyoshi, M, Shirakawa, M.
登録日2012-09-21
公開日2013-01-16
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4
J.Biol.Chem., 288, 2013
3VYQ
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Crystal structure of the methyl CpG Binding Domain of MBD4 in complex with the 5mCG/TG sequence in space group P1
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*CP*AP*TP*CP*(5CM)P*GP*GP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*CP*TP*GP*GP*AP*TP*GP*T)-3'), ...
著者Otani, J, Arita, K, Kato, T, Kinoshita, M, Ariyoshi, M, Shirakawa, M.
登録日2012-10-02
公開日2013-01-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.525 Å)
主引用文献Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4
J.Biol.Chem., 288, 2013
3W6H
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BU of 3w6h by Molmil
Crystal structure of 19F probe-labeled hCAI in complex with acetazolamide
分子名称: 1-(2-ethoxyethoxy)-3,5-bis(trifluoromethyl)benzene, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 1, ...
著者Takaoka, Y, Kioi, Y, Morito, A, Otani, J, Arita, K, Ashihara, E, Ariyoshi, M, Tochio, H, Shirakawa, M, Hamachi, I.
登録日2013-02-14
公開日2013-03-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.964 Å)
主引用文献Quantitative Comparison of Protein Dynamics in Live Cells and In Vitro by In-Cell 19F-NMR
To be published
3W6I
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Crystal structure of 19F probe-labeled hCAI
分子名称: 1-(2-ethoxyethoxy)-3,5-bis(trifluoromethyl)benzene, Carbonic anhydrase 1, ZINC ION
著者Takaoka, Y, Kioi, Y, Morito, A, Otani, J, Arita, K, Ashihara, E, Ariyoshi, M, Tochio, H, Shirakawa, M, Hamachi, I.
登録日2013-02-14
公開日2013-03-13
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.693 Å)
主引用文献Quantitative Comparison of Protein Dynamics in Live Cells and In Vitro by In-Cell 19F-NMR
To be published
3VXV
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BU of 3vxv by Molmil
Crystal structure of methyl CpG Binding Domain of MBD4 in complex with the 5mCG/TG sequence
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(*GP*TP*CP*AP*CP*TP*AP*CP*(5CM)P*GP*GP*AP*CP*A)-3'), ...
著者Otani, J, Arita, K, Kato, T, Kinoshita, M, Ariyoshi, M, Shirakawa, M.
登録日2012-09-21
公開日2013-01-16
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4
J.Biol.Chem., 288, 2013
3A1B
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Crystal structure of the DNMT3A ADD domain in complex with histone H3
分子名称: 1,2-ETHANEDIOL, DNA (cytosine-5)-methyltransferase 3A, Histone H3.1, ...
著者Otani, J, Arita, K, Ariyoshi, M, Shirakawa, M.
登録日2009-03-28
公開日2009-11-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.292 Å)
主引用文献Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain
Embo Rep., 10, 2009
3A1A
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Crystal Structure of the DNMT3A ADD domain
分子名称: 1,2-ETHANEDIOL, DNA (cytosine-5)-methyltransferase 3A, ZINC ION
著者Otani, J, Arita, K, Ariyoshi, M, Shirakawa, M.
登録日2009-03-28
公開日2009-11-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain
Embo Rep., 10, 2009
5Y9Z
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Crystal structure of rat hematopoietic prostaglandin D synthase
分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, GLUTATHIONE, ...
著者Kamo, M, Furubayashi, N, Inaka, K, Tanaka, H, Aritake, K, Urade, Y.
登録日2017-08-29
公開日2018-09-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.09 Å)
主引用文献Crystal structure of rat hematopoietic prostaglandin D synthase
To Be Published
5YWX
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Crystal structure of hematopoietic prostaglandin D synthase in complex with F092
分子名称: GLUTATHIONE, GLYCEROL, Hematopoietic prostaglandin D synthase, ...
著者Kamo, M, Furubayashi, N, Inaka, K, Aritake, K, Omura, A, Tanaka, A.
登録日2017-11-30
公開日2018-09-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Characterization of crystal water molecules in a high-affinity inhibitor and hematopoietic prostaglandin D synthase complex by interaction energy studies.
Bioorg. Med. Chem., 26, 2018
5YX1
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Crystal structure of hematopoietic prostaglandin D synthase in complex with U004
分子名称: GLUTATHIONE, GLYCEROL, Hematopoietic prostaglandin D synthase, ...
著者Kamo, M, Furubayashi, N, Inaka, K, Aritake, K, Urade, Y, Takaya, D, Tanaka, A.
登録日2017-12-01
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Crystal structure of hematopoietic prostaglandin D synthase in complex with U004
To Be Published
5YWE
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Crystal structure of hematopoietic prostaglandin D synthase apo form
分子名称: GLUTATHIONE, GLYCEROL, Hematopoietic prostaglandin D synthase, ...
著者Kamo, M, Furubayashi, N, Inaka, K, Aritake, K, Urade, Y.
登録日2017-11-29
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Crystal structure of hematopoietic prostaglandin D synthase apo form
To Be Published
1V40
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First Inhibitor Complex Structure of Human Hematopoietic Prostaglandin D Synthase
分子名称: 3-(1,3-BENZOTHIAZOL-2-YL)-2-(1,4-DIOXO-1,2,3,4-TETRAHYDROPHTHALAZIN-6-YL)-5-[(E)-2-PHENYLVINYL]-3H-TETRAAZOL-2-IUM, GLUTATHIONE, GLYCEROL, ...
著者Inoue, T, Okano, Y, Kado, Y, Aritake, K, Irikura, D, Uodome, N, Kinugasa, S, Okazaki, N, Matsumura, H, Kai, Y, Urade, Y.
登録日2003-11-07
公開日2004-11-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献First determination of the inhibitor complex structure of human hematopoietic prostaglandin D synthase.
J.Biochem.(Tokyo), 135, 2004
2CZU
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lipocalin-type prostaglandin D synthase
分子名称: Prostaglandin-H2 D-isomerase
著者Kumasaka, T, Irikura, D, Ago, H, Aritake, K, Yamamoto, M, Inoue, T, Miyano, M, Urade, Y, Hayaishi, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-07-17
公開日2006-10-03
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of the catalytic mechanism operating in open-closed conformers of lipocalin type prostaglandin D synthase.
J.Biol.Chem., 284, 2009
2CZT
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lipocalin-type prostaglandin D synthase
分子名称: Prostaglandin-H2 D-isomerase
著者Kumasaka, T, Irikura, D, Ago, H, Aritake, K, Yamamoto, M, Inoue, T, Miyano, M, Urade, Y, Hayaishi, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-07-17
公開日2006-10-03
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of the catalytic mechanism operating in open-closed conformers of lipocalin type prostaglandin D synthase.
J.Biol.Chem., 284, 2009
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