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PDB: 32 件

8JYR
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Crystal structure of anti-HER2 antibody H2Mab-119 in complex with HER2 domain I
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, H2Mab-119 VH-CH1, H2Mab-119 light chain, ...
著者Arimori, T, Takagi, J.
登録日2023-07-03
公開日2024-03-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Locally misfolded HER2 expressed on cancer cells is a promising target for development of cancer-specific antibodies.
Structure, 32, 2024
8JYQ
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BU of 8jyq by Molmil
Crystal structure of cancer-specific anti-HER2 antibody H2Mab-214 in complex with epitope peptide
分子名称: H2CasMab-1 VH(S112C),SARAH, H2CasMab-1 VL,SARAH(S37C), H2CasMab-1 epitope peptide
著者Arimori, T, Takagi, J.
登録日2023-07-03
公開日2024-03-13
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Locally misfolded HER2 expressed on cancer cells is a promising target for development of cancer-specific antibodies.
Structure, 32, 2024
6LZ4
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BU of 6lz4 by Molmil
Crystal structure of PMab-1 Fv-clasp fragment with its antigen peptide
分子名称: MAP peptide, PMab-1 VH(S112C)-SARAH Chimera, PMab-1 VL-SARAH(S37C) Chimera
著者Arimori, T, Takagi, J.
登録日2020-02-18
公開日2020-05-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Site-specific epitope insertion into recombinant proteins using the MAP tag system.
J.Biochem., 168, 2020
3L85
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BU of 3l85 by Molmil
Crystal structure of human NUDT5 complexed with 8-oxo-dGMP
分子名称: 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE, ADP-sugar pyrophosphatase
著者Arimori, T, Yamagata, Y.
登録日2009-12-29
公開日2011-01-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Diverse substrate recognition and hydrolysis mechanisms of human NUDT5
Nucleic Acids Res., 39, 2011
3AC9
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BU of 3ac9 by Molmil
Crystal structure of human NUDT5 complexed with 8-oxo-dGDP and manganese
分子名称: 2'-deoxy-8-oxoguanosine 5'-(trihydrogen diphosphate), ADP-sugar pyrophosphatase, MANGANESE (II) ION
著者Arimori, T, Yamagata, Y.
登録日2009-12-30
公開日2011-01-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Diverse substrate recognition and hydrolysis mechanisms of human NUDT5
Nucleic Acids Res., 39, 2011
3ACA
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Crystal structure of human NUDT5 complexed with 8-oxo-dADP and manganese
分子名称: 8-oxo-7,8-dihydro-2'-deoxy-adenosine-5'-diphosphate, ADP-sugar pyrophosphatase, MANGANESE (II) ION
著者Arimori, T, Yamagata, Y.
登録日2009-12-30
公開日2011-01-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Diverse substrate recognition and hydrolysis mechanisms of human NUDT5
Nucleic Acids Res., 39, 2011
7DMU
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BU of 7dmu by Molmil
Structure of SARS-CoV-2 spike receptor-binding domain complexed with high affinity ACE2 mutant 3N39
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Arimori, T, Takagi, J.
登録日2020-12-07
公開日2020-12-23
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2.
Nat Commun, 12, 2021
7CEC
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BU of 7cec by Molmil
Structure of alpha6beta1 integrin in complex with laminin-511
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Arimori, T, Miyazaki, N, Takagi, J.
登録日2020-06-22
公開日2021-06-23
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural mechanism of laminin recognition by integrin.
Nat Commun, 12, 2021
5GKR
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BU of 5gkr by Molmil
Crystal structure of SLE patient-derived anti-DNA antibody in complex with oligonucleotide
分子名称: DNA (5'-D(P*TP*TP*TP*T)-3'), IgG2, Fab (heavy chain), ...
著者Arimori, T, Sakakibara, S, Kikutani, H, Takagi, J.
登録日2016-07-05
公開日2017-07-05
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus
Sci Rep, 7, 2017
5GKS
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BU of 5gks by Molmil
Crystal structure of SLE patient-derived anti-DNA antibody
分子名称: IgG2, Fab (heavy chain), PHOSPHATE ION, ...
著者Arimori, T, Sakakibara, S, Kikutani, H, Takagi, J.
登録日2016-07-05
公開日2017-07-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus
Sci Rep, 7, 2017
7CEA
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BU of 7cea by Molmil
Crystal structure of HUTS-4 Fv-clasp fragment
分子名称: HUTS-4 VH(S112C)-SARAH, HUTS-4 VL(C87Y)-SARAH(S37C)
著者Arimori, T, Takagi, J.
登録日2020-06-22
公開日2021-06-23
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural mechanism of laminin recognition by integrin.
Nat Commun, 12, 2021
7CEB
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BU of 7ceb by Molmil
Crystal structure of alpha6beta1 integrin headpiece
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-6, ...
著者Arimori, T, Takagi, J.
登録日2020-06-22
公開日2021-06-23
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Structural mechanism of laminin recognition by integrin.
Nat Commun, 12, 2021
3W6E
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BU of 3w6e by Molmil
Crystal structure of catalytic domain of chitinase from Ralstonia sp. A-471 (E162Q)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Lysozyme-like chitinolytic enzyme
著者Arimori, T, Kawamoto, N, Okazaki, N, Nakazawa, M, Miyatake, K, Fukamizo, T, Ueda, M, Tamada, T.
登録日2013-02-14
公開日2013-05-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal Structures of the Catalytic Domain of a Novel Glycohydrolase Family 23 Chitinase from Ralstonia sp. A-471 Reveals a Unique Arrangement of the Catalytic Residues for Inverting Chitin Hydrolysis
J.Biol.Chem., 288, 2013
3W6D
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BU of 3w6d by Molmil
Crystal structure of catalytic domain of chitinase from Ralstonia sp. A-471 (E141Q) in complex with tetrasaccharide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysozyme-like chitinolytic enzyme
著者Arimori, T, Kawamoto, N, Okazaki, N, Nakazawa, M, Miyatake, K, Fukamizo, T, Ueda, M, Tamada, T.
登録日2013-02-14
公開日2013-05-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal Structures of the Catalytic Domain of a Novel Glycohydrolase Family 23 Chitinase from Ralstonia sp. A-471 Reveals a Unique Arrangement of the Catalytic Residues for Inverting Chitin Hydrolysis
J.Biol.Chem., 288, 2013
3W6B
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BU of 3w6b by Molmil
Crystal structure of catalytic domain of chitinase from Ralstonia sp. A-471
分子名称: GLYCEROL, Lysozyme-like chitinolytic enzyme
著者Arimori, T, Kawamoto, N, Okazaki, N, Nakazawa, M, Miyatake, K, Fukamizo, T, Ueda, M, Tamada, T.
登録日2013-02-14
公開日2013-05-15
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures of the Catalytic Domain of a Novel Glycohydrolase Family 23 Chitinase from Ralstonia sp. A-471 Reveals a Unique Arrangement of the Catalytic Residues for Inverting Chitin Hydrolysis
J.Biol.Chem., 288, 2013
3W6F
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BU of 3w6f by Molmil
Crystal structure of catalytic domain of chitinase from Ralstonia sp. A-471 (E162Q) in complex with disaccharide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysozyme-like chitinolytic enzyme
著者Arimori, T, Kawamoto, N, Okazaki, N, Nakazawa, M, Miyatake, K, Fukamizo, T, Ueda, M, Tamada, T.
登録日2013-02-14
公開日2013-05-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of the Catalytic Domain of a Novel Glycohydrolase Family 23 Chitinase from Ralstonia sp. A-471 Reveals a Unique Arrangement of the Catalytic Residues for Inverting Chitin Hydrolysis
J.Biol.Chem., 288, 2013
3W6C
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BU of 3w6c by Molmil
Crystal structure of catalytic domain of chitinase from Ralstonia sp. A-471 in complex with disaccharide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysozyme-like chitinolytic enzyme
著者Arimori, T, Kawamoto, N, Okazaki, N, Nakazawa, M, Miyatake, K, Fukamizo, T, Ueda, M, Tamada, T.
登録日2013-02-14
公開日2013-05-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of the Catalytic Domain of a Novel Glycohydrolase Family 23 Chitinase from Ralstonia sp. A-471 Reveals a Unique Arrangement of the Catalytic Residues for Inverting Chitin Hydrolysis
J.Biol.Chem., 288, 2013
3WC3
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BU of 3wc3 by Molmil
Crystal structure of endo-1,4-beta-glucanase from Eisenia fetida
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CITRATE ANION, ...
著者Arimori, T, Tamada, T.
登録日2013-05-24
公開日2013-10-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of endo-1,4-beta-glucanase from Eisenia fetida
J.SYNCHROTRON RADIAT., 20, 2013
5XCU
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BU of 5xcu by Molmil
Crystal structure of 12CA5 Fv-clasp fragment with its antigen peptide
分子名称: HA peptide, SULFATE ION, VH(S112C)-SARAH chimera,VH(S112C)-SARAH chimera, ...
著者Arimori, T, Takagi, J.
登録日2017-03-23
公開日2017-10-04
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.454 Å)
主引用文献Fv-clasp: An Artificially Designed Small Antibody Fragment with Improved Production Compatibility, Stability, and Crystallizability
Structure, 25, 2017
5XCT
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BU of 5xct by Molmil
Crystal structure of P20.1 Fv-clasp fragment with its antigen peptide
分子名称: C8 peptide, CHLORIDE ION, VH(S112C)-SARAH chimera, ...
著者Arimori, T, Takagi, J.
登録日2017-03-23
公開日2017-10-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献Fv-clasp: An Artificially Designed Small Antibody Fragment with Improved Production Compatibility, Stability, and Crystallizability
Structure, 25, 2017
5XCV
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BU of 5xcv by Molmil
Crystal structure of NZ-1 Fv-clasp fragment with its antigen peptide
分子名称: CALCIUM ION, PA14 peptide, VH(S112C)-SARAH chimera,VH(S112C)-SARAH chimera, ...
著者Arimori, T, Takagi, J.
登録日2017-03-23
公開日2017-10-11
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.143 Å)
主引用文献Fv-clasp: An Artificially Designed Small Antibody Fragment with Improved Production Compatibility, Stability, and Crystallizability
Structure, 25, 2017
5XCR
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BU of 5xcr by Molmil
Crystal structure of P20.1 Fv-clasp fragment with its antigen peptide
分子名称: C8 peptide, VH-SARAH(Y35C) chimera, VL-SARAH(M24C) chimera
著者Arimori, T, Takagi, J.
登録日2017-03-23
公開日2017-10-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Fv-clasp: An Artificially Designed Small Antibody Fragment with Improved Production Compatibility, Stability, and Crystallizability
Structure, 25, 2017
5XCX
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Crystal structure of TS2/16 Fv-clasp fragment
分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, GLYCEROL, PHOSPHATE ION, ...
著者Arimori, T, Takagi, J.
登録日2017-03-23
公開日2017-10-04
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Fv-clasp: An Artificially Designed Small Antibody Fragment with Improved Production Compatibility, Stability, and Crystallizability
Structure, 25, 2017
5XCS
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BU of 5xcs by Molmil
Crystal structure of 12CA5 Fv-clasp fragment with its antigen peptide
分子名称: HA peptide, SULFATE ION, VH-SARAH(Y35C) chimera, ...
著者Arimori, T, Takagi, J.
登録日2017-03-23
公開日2017-10-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Fv-clasp: An Artificially Designed Small Antibody Fragment with Improved Production Compatibility, Stability, and Crystallizability
Structure, 25, 2017
5XCQ
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BU of 5xcq by Molmil
Crystal structure of P20.1 Fv-clasp fragment with its antigen peptide
分子名称: C8 peptide, SULFATE ION, VH-SARAH(Y35C)chimera, ...
著者Arimori, T, Takagi, J.
登録日2017-03-23
公開日2017-10-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.313 Å)
主引用文献Fv-clasp: An Artificially Designed Small Antibody Fragment with Improved Production Compatibility, Stability, and Crystallizability
Structure, 25, 2017

 

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