3L85

Crystal structure of human NUDT5 complexed with 8-oxo-dGMP

Summary for 3L85

Entry DOI	10.2210/pdb3l85/pdb
Related	3AC9 3ACA
Descriptor	ADP-sugar pyrophosphatase, 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE (3 entities in total)
Functional Keywords	nudix motif, magnesium, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	44013.63
Authors	Arimori, T.,Yamagata, Y. (deposition date: 2009-12-29, release date: 2011-01-12, Last modification date: 2023-11-01)
Primary citation	Arimori, T.,Tamaoki, H.,Nakamura, T.,Kamiya, H.,Ikemizu, S.,Takagi, Y.,Ishibashi, T.,Harashima, H.,Sekiguchi, M.,Yamagata, Y. Diverse substrate recognition and hydrolysis mechanisms of human NUDT5 Nucleic Acids Res., 39:8972-8983, 2011 Cited by PubMed: 21768126 DOI: 10.1093/nar/gkr575 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.301 Å)

Structure validation