5T4K
 
 | | PLP and GABA Trigger GabR-Mediated Transcription Regulation in Bacillus subsidies via External Aldimine Formation | | 分子名称: | (4S)-5-fluoro-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid, HTH-type transcriptional regulatory protein GabR | | 著者 | Wu, R, Sanishvili, R, Belitsky, B.R, Juncosa, J.I, Le, H.V, Lehrer, H.J.S, Farley, M, Silverman, R.B, Petsko, G.A, Ringe, D, Liu, D. | | 登録日 | 2016-08-29 | | 公開日 | 2017-03-29 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.245 Å) | | 主引用文献 | PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5T4J
 | | PLP and GABA Trigger GabR-Mediated Transcription Regulation in Bacillus subsidies via External Aldimine Formation | | 分子名称: | GAMMA-AMINO-BUTANOIC ACID, HTH-type transcriptional regulatory protein GabR, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Wu, R, Sanishvili, R, Belitsky, B.R, Juncosa, J.I, Le, H.V, Lehrer, H.J.S, Farley, M, Silverman, R.B, Petsko, G.A, Ringe, D, Liu, D. | | 登録日 | 2016-08-29 | | 公開日 | 2017-03-29 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.231 Å) | | 主引用文献 | PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
4ZSW
 | | Pig Brain GABA-AT inactivated by (E)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic acid | | 分子名称: | (1S)-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]cyclopent-3-ene-1,3-dicarboxylic acid, 4-aminobutyrate aminotransferase, mitochondrial, ... | | 著者 | Wu, R, Lee, H, Le, H.V, Doud, E, Sanishvili, R, Compton, P, Kelleher, N.L, Silverman, R.B, Liu, D. | | 登録日 | 2015-05-14 | | 公開日 | 2015-07-08 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid.
Acs Chem.Biol., 10, 2015
|
|
4ZSY
 | | Pig Brain GABA-AT inactivated by (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic acid. | | 分子名称: | (1S)-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]cyclopent-3-ene-1,3-dicarboxylic acid, 4-aminobutyrate aminotransferase, mitochondrial, ... | | 著者 | Wu, R, Lee, H, Le, H.V, Doud, E, Sanishvili, R, Compton, P, Kelleher, N.L, Silverman, R.B, Liu, D. | | 登録日 | 2015-05-14 | | 公開日 | 2015-07-08 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid.
Acs Chem.Biol., 10, 2015
|
|
1DNO
 | | A-DNA/RNA DODECAMER R(GCG)D(TATACGC) MG BINDING SITES | | 分子名称: | DNA/RNA (5'-R(*GP*CP*GP)-D(*TP*AP*TP*AP*CP*GP*C)-3'), MAGNESIUM ION | | 著者 | Robinson, H, Gao, Y.-G, Sanishvili, R, Joachimiak, A, Wang, A.H.-J. | | 登録日 | 1999-12-16 | | 公開日 | 2000-04-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Hexahydrated magnesium ions bind in the deep major groove and at the outer mouth of A-form nucleic acid duplexes.
Nucleic Acids Res., 28, 2000
|
|
1DNT
 | | RNA/DNA DODECAMER R(GC)D(GTATACGC) WITH MAGNESIUM BINDING SITES | | 分子名称: | DNA/RNA (5'-R(*GP*CP)-D(*GP*TP*AP*TP*AP*CP*GP*C)-3'), MAGNESIUM ION | | 著者 | Robinson, H, Gao, Y.-G, Sanishvili, R, Joachimiak, A, Wang, A.H.-J. | | 登録日 | 1999-12-16 | | 公開日 | 2000-04-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Hexahydrated magnesium ions bind in the deep major groove and at the outer mouth of A-form nucleic acid duplexes.
Nucleic Acids Res., 28, 2000
|
|
1DNX
 | | RNA/DNA DODECAMER R(G)D(CGTATACGC) WITH MAGNESIUM BINDING SITES | | 分子名称: | DNA/RNA (5'-R(*GP)-D(*CP*GP*TP*AP*TP*AP*CP*GP*C)-3'), MAGNESIUM ION | | 著者 | Robinson, H, Gao, Y.-G, Sanishvili, R, Joachimiak, A, Wang, A.H.-J. | | 登録日 | 1999-12-16 | | 公開日 | 2000-04-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Hexahydrated magnesium ions bind in the deep major groove and at the outer mouth of A-form nucleic acid duplexes.
Nucleic Acids Res., 28, 2000
|
|
1US0
 | | Human Aldose Reductase in complex with NADP+ and the inhibitor IDD594 at 0.66 Angstrom | | 分子名称: | ALDOSE REDUCTASE, CITRIC ACID, IDD594, ... | | 著者 | Howard, E.I, Sanishvili, R, Cachau, R.E, Mitschler, A, Chevrier, B, Barth, P, Lamour, V, Van Zandt, M, Sibley, E, Bon, C, Moras, D, Schneider, T.R, Joachimiak, A, Podjarny, A. | | 登録日 | 2003-11-16 | | 公開日 | 2004-05-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (0.66 Å) | | 主引用文献 | Ultrahigh Resolution Drug Design I: Details of Interactions in Human Aldose Reductase-Inhibitor Complex at 0.66 A.
Proteins, 55, 2004
|
|
1DPN
 | | B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE | | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*TP*CP*GP*CP*G)-3'), MAGNESIUM ION | | 著者 | Egli, M, Tereshko, V, Teplova, M, Minasov, G, Joachimiak, A, Sanishvili, R, Weeks, C.M, Miller, R, Maier, M.A, An, H, Dan Cook, P, Manoharan, M. | | 登録日 | 1999-12-27 | | 公開日 | 2000-04-04 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | | 主引用文献 | X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution.
Biopolymers, 48, 1998
|
|
1D8X
 | | CRYSTAL STRUCTURE OF DNA SHEARED TANDEM G A BASE PAIRS | | 分子名称: | 5'-D(*CP*CP*GP*AP*AP*TP*GP*AP*GP*G)-3', COBALT HEXAMMINE(III), MAGNESIUM ION | | 著者 | Gao, Y.-G, Robinson, H, Sanishvili, R, Joachimiak, A, Wang, A.H.-J. | | 登録日 | 1999-10-26 | | 公開日 | 1999-11-05 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structure and recognition of sheared tandem G x A base pairs associated with human centromere DNA sequence at atomic resolution.
Biochemistry, 38, 1999
|
|
1DPL
 | | A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE | | 分子名称: | 5'-D(*GP*CP*GP*TP*AP*(T23)P*AP*CP*GP*C)-3', MAGNESIUM ION, SPERMINE | | 著者 | Egli, M, Tereshko, V, Teplova, M, Minasov, G, Joachimiak, A, Sanishvili, R, Weeks, C.M, Miller, R, Maier, M.A, An, H, Dan Cook, P, Manoharan, M. | | 登録日 | 1999-12-27 | | 公開日 | 2000-04-04 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (0.83 Å) | | 主引用文献 | X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution.
Biopolymers, 48, 1998
|
|
1DNZ
 | | A-DNA DECAMER ACCGGCCGGT WITH MAGNESIUM BINDING SITES | | 分子名称: | DNA (5'-D(*AP*CP*CP*GP*GP*CP*CP*GP*GP*T)-3'), MAGNESIUM ION | | 著者 | Robinson, H, Gao, Y.-G, Sanishvili, R, Joachimiak, A, Wang, A.H.-J. | | 登録日 | 1999-12-17 | | 公開日 | 2000-04-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Hexahydrated magnesium ions bind in the deep major groove and at the outer mouth of A-form nucleic acid duplexes.
Nucleic Acids Res., 28, 2000
|
|
1SRV
 | | THERMUS THERMOPHILUS GROEL (HSP60 CLASS) FRAGMENT (APICAL DOMAIN) COMPRISING RESIDUES 192-336 | | 分子名称: | PROTEIN (GROEL (HSP60 CLASS)) | | 著者 | Walsh, M.A, Dementieva, I, Evans, G, Sanishvili, R, Joachimiak, A. | | 登録日 | 1999-03-02 | | 公開日 | 1999-03-12 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Taking MAD to the extreme: ultrafast protein structure determination.
Acta Crystallogr.,Sect.D, 55, 1999
|
|
1HRU
 | | THE STRUCTURE OF THE YRDC GENE PRODUCT FROM E.COLI | | 分子名称: | PHOSPHATE ION, YRDC GENE PRODUCT | | 著者 | Teplova, M, Tereshko, V, Sanishvili, R, Joachimiak, A, Bushueva, T, Anderson, W.F, Egli, M, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2000-12-21 | | 公開日 | 2001-01-31 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structure of the yrdC gene product from Escherichia coli reveals a new fold and suggests a role in RNA binding.
Protein Sci., 9, 2000
|
|
1I3W
 | | ACTINOMYCIN D BINDING TO CGATCGATCG | | 分子名称: | 5'-D(*C*GP*AP*TP*CP*GP*AP*(BRU)P*CP*GP)-3', ACTINOMYCIN D | | 著者 | Robinson, H, Gao, Y.-G, Yang, X.-L, Sanishvili, R, Joachimiak, A, Wang, A.H.-J. | | 登録日 | 2001-02-17 | | 公開日 | 2001-05-21 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystallographic Analysis of a Novel Complex of Actinomycin D Bound to the DNA Decamer Cgatcgatcg.
Biochemistry, 40, 2001
|
|
1NOG
 | | Crystal Structure of Conserved Protein 0546 from Thermoplasma Acidophilum | | 分子名称: | conserved hypothetical protein TA0546 | | 著者 | Saridakis, V, Sanishvili, R, Iakounine, A, Xu, X, Pennycooke, M, Gu, J, Joachimiak, A, Arrowsmith, C.H, Edwards, A.M, Christendat, D, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2003-01-16 | | 公開日 | 2003-07-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | The structural basis for methylmalonic aciduria. The crystal structure of archaeal ATP:cobalamin adenosyltransferase.
J.Biol.Chem., 279, 2004
|
|
1DCR
 | | CRYSTAL STRUCTURE OF DNA SHEARED TANDEM G-A BASE PAIRS | | 分子名称: | 5'-D(*CP*CP*GP*AP*AP*(BRU)P*GP*AP*GP*G)-3', MAGNESIUM ION, SODIUM ION, ... | | 著者 | Gao, Y.-G, Robinson, H, Sanishvili, R, Joachimiak, A, Wang, A.H.-J. | | 登録日 | 1999-11-05 | | 公開日 | 1999-11-19 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure and recognition of sheared tandem G x A base pairs associated with human centromere DNA sequence at atomic resolution.
Biochemistry, 38, 1999
|
|
1D9R
 | | CRYSTAL STRUCTURE OF DNA SHEARED TANDEM G-A BASE PAIRS | | 分子名称: | 5'-D(*CP*CP*GP*AP*AP*(BRU)P*GP*AP*GP*G)-3', COBALT HEXAMMINE(III) | | 著者 | Gao, Y.-G, Robinson, H, Sanishvili, R, Joachimiak, A, Wang, A.H.-J. | | 登録日 | 1999-10-29 | | 公開日 | 1999-11-05 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure and recognition of sheared tandem G x A base pairs associated with human centromere DNA sequence at atomic resolution.
Biochemistry, 38, 1999
|
|
