4JN4
| Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK, GLYCEROL, ... | Authors: | Qi, R, Sarbeng, E.B, Liu, Q, Le, K.Q, Xu, X, Xu, H, Yang, J, Wong, J.L, Vorvis, C, Hendrickson, W.A, Zhou, L, Liu, Q. | Deposit date: | 2013-03-14 | Release date: | 2013-05-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP. Nat.Struct.Mol.Biol., 20, 2013
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3OF1
| Crystal Structure of Bcy1, the Yeast Regulatory Subunit of PKA | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP-dependent protein kinase regulatory subunit | Authors: | Rinaldi, J, Wu, J, Yang, J, Ralston, C.Y, Sankaran, B, Moreno, S, Taylor, S.S. | Deposit date: | 2010-08-13 | Release date: | 2010-12-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Structure of Yeast Regulatory Subunit: A Glimpse into the Evolution of PKA Signaling. Structure, 18, 2010
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6K93
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6K9F
| Structure of unknow protein 4 | Descriptor: | Caspase recruitment domain-containing protein 8 | Authors: | Gong, Q, Xu, C, Zhang, J, Boo, Z.Z, Wu, B. | Deposit date: | 2019-06-15 | Release date: | 2020-09-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8. Nat Commun, 12, 2021
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4E2K
| The structure of the S. aureus DnaG RNA Polymerase Domain | Descriptor: | BENZAMIDINE, DNA primase | Authors: | Rymer, R.U, Solorio, F.A, Clement, C, Corn, J.E, Wang, J.D, Berger, J.M. | Deposit date: | 2012-03-08 | Release date: | 2012-08-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases. Structure, 20, 2012
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5X3R
| Crystal structure of the SmcR complexed with QStatin | Descriptor: | 1-(5-bromanylthiophen-2-yl)sulfonylpyrazole, LuxR family transcriptional regulator, SULFATE ION | Authors: | Jang, S.Y, Hwang, J, Kim, M.H. | Deposit date: | 2017-02-07 | Release date: | 2018-01-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | QStatin, a Selective Inhibitor of Quorum Sensing inVibrioSpecies MBio, 9, 2018
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3ID2
| Crystal Structure of RseP PDZ2 domain | Descriptor: | IODIDE ION, Regulator of sigma E protease | Authors: | Li, X, Wang, B, Feng, L, Wang, J, Shi, Y. | Deposit date: | 2009-07-20 | Release date: | 2009-08-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.089 Å) | Cite: | Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage Proc.Natl.Acad.Sci.USA, 106, 2009
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6JZO
| Structure of the mouse TRPC4 ion channel | Descriptor: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ... | Authors: | Duan, J, Li, Z, Li, J, Zhang, J. | Deposit date: | 2019-05-03 | Release date: | 2020-10-21 | Last modified: | 2021-05-05 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Structure of the mouse TRPC4 ion channel To Be Published
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5H2Z
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6MG1
| C-terminal bZIP domain of human C/EBPbeta with 16bp Methylated Oligonucleotide Containing Consensus Recognition Sequence-C2 Crystal Form | Descriptor: | 1,2-ETHANEDIOL, 16-bp methylated oligonucleotide, CCAAT/enhancer-binding protein beta, ... | Authors: | Horton, J.R, Cheng, X, Yang, J. | Deposit date: | 2018-09-12 | Release date: | 2018-12-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural basis for effects of CpA modifications on C/EBP beta binding of DNA. Nucleic Acids Res., 47, 2019
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3ID4
| Crystal Structure of RseP PDZ2 domain fused GKASPV peptide | Descriptor: | Regulator of sigma E protease | Authors: | Li, X, Wang, B, Feng, L, Wang, J, Shi, Y. | Deposit date: | 2009-07-20 | Release date: | 2009-08-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.604 Å) | Cite: | Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage Proc.Natl.Acad.Sci.USA, 106, 2009
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4CKB
| Vaccinia virus capping enzyme complexed with GTP and SAH | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MRNA-CAPPING ENZYME CATALYTIC SUBUNIT, MRNA-CAPPING ENZYME REGULATORY SUBUNIT, ... | Authors: | Kyrieleis, O.J.P, Chang, J, de la Pena, M, Shuman, S, Cusack, S. | Deposit date: | 2014-01-02 | Release date: | 2014-03-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of Vaccinia Virus Mrna Capping Enzyme Provides Insights Into the Mechanism and Evolution of the Capping Apparatus. Structure, 22, 2014
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4EDV
| The structure of the S. aureus DnaG RNA Polymerase Domain bound to pppGpp and Manganese | Descriptor: | BENZAMIDINE, DNA primase, MANGANESE (II) ION, ... | Authors: | Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M. | Deposit date: | 2012-03-27 | Release date: | 2012-07-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases. Structure, 20, 2012
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7E2B
| GDPD mutant complex from Pyrococcus furiosus DSM 3638 | Descriptor: | CHOLINE ION, Glycerophosphodiester phosphodiesterase, MAGNESIUM ION, ... | Authors: | Wang, Y.H, Wang, J, Wang, F.H. | Deposit date: | 2021-02-05 | Release date: | 2022-02-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Observation of the GPC production during hydrolysis of LPC by GDPD D60A from Pyrococcus furiosus DSM 3638 To Be Published
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7E0V
| GDPD from Pyrococcus furiosus DSM 3638 | Descriptor: | Glycerophosphodiester phosphodiesterase | Authors: | Wang, Y.H, Wang, J, Wang, F.H. | Deposit date: | 2021-01-28 | Release date: | 2022-02-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of Bomgl, a monoacylglycerol lipase from marine Bacillus To Be Published
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7E2A
| GDPD mutant from Pyrococcus furiosus DSM 3638 | Descriptor: | Glycerophosphodiester phosphodiesterase | Authors: | Wang, Y.H, Wang, J, Wang, F.H. | Deposit date: | 2021-02-05 | Release date: | 2022-02-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Crystal structure of glycerophoshphodiester phospodiesterase D60A mutant from Pyrococcus furiosus DSM To Be Published
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2BAZ
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5GND
| Structure of Deg protease HhoA from Synechocystis sp. PCC 6803 | Descriptor: | Putative serine protease HhoA, SODIUM ION, UNK-UNK-UNK-UNK-TRP, ... | Authors: | Dong, W, Wang, J, Liu, L. | Deposit date: | 2016-07-20 | Release date: | 2016-09-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the zinc-bound HhoA protease from Synechocystis sp. PCC 6803 Febs Lett., 590, 2016
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6LOX
| Crystal Structure of human glutaminase with macrocyclic inhibitor | Descriptor: | (E)-15,22-Dioxa-4,11-diaza-5(2,5)-thiadiazola-10(3,6)-pyridazina-1,14(1,3)-dibenzenacyclodocosaphan-18-ene-3,12-dione, Glutaminase kidney isoform, mitochondrial | Authors: | Bian, J, Li, Z, Xu, X, Wang, J, Li, L. | Deposit date: | 2020-01-07 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure-Enabled Discovery of Novel Macrocyclic Inhibitors Targeting Glutaminase 1 Allosteric Binding Site. J.Med.Chem., 64, 2021
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4G27
| Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant and phenylurea | Descriptor: | 1-phenylurea, CALCIUM ION, Calmodulin, ... | Authors: | Zhang, M, Pascal, J.M, Zhang, J.-F. | Deposit date: | 2012-07-11 | Release date: | 2012-09-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Identification of the functional binding pocket for compounds targeting small-conductance Ca(2+)-activated potassium channels. Nat Commun, 3, 2012
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7E04
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4G6F
| Crystal Structure of 10E8 Fab in Complex with an HIV-1 gp41 Peptide | Descriptor: | 10E8 Heavy Chain, 10E8 Light Chain, gp41 MPER Peptide | Authors: | Ofek, G, Huang, J, Connors, M, Kwong, P.D. | Deposit date: | 2012-07-19 | Release date: | 2012-09-26 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Broad and potent neutralization of HIV-1 by a gp41-specific human antibody. Nature, 491, 2012
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4CC5
| Fragment-Based Discovery of 6 Azaindazoles As Inhibitors of Bacterial DNA Ligase | Descriptor: | 2-chloranyl-6-(1H-1,2,4-triazol-3-yl)pyrazine, DNA LIGASE, SULFATE ION | Authors: | Howard, S, Amin, N, Benowitz, A.B, Chiarparin, E, Cui, H, Deng, X, Heightman, T.D, Holmes, D.J, Hopkins, A, Huang, J, Jin, Q, Kreatsoulas, C, Martin, A.C.L, Massey, F, McCloskey, L, Mortenson, P.N, Pathuri, P, Tisi, D, Williams, P.A. | Deposit date: | 2013-10-18 | Release date: | 2014-06-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Fragment-Based Discovery of 6-Azaindazoles as Inhibitors of Bacterial DNA Ligase. Acs Med.Chem.Lett., 4, 2013
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3HIF
| The crystal structure of apo wild type CAP at 3.6 A resolution. | Descriptor: | Catabolite gene activator | Authors: | Steitz, T.A, Sharma, H, Wang, J, Kong, J, Yu, S. | Deposit date: | 2009-05-19 | Release date: | 2009-09-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.59 Å) | Cite: | Structure of apo-CAP reveals that large conformational changes are necessary for DNA binding. Proc.Natl.Acad.Sci.USA, 106, 2009
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6MG3
| V285A Mutant of the C-terminal bZIP domain of human C/EBPbeta with 16bp Methylated Oligonucleotide Containing Consensus Recognition Sequence | Descriptor: | 1,2-ETHANEDIOL, 16-bp methylated oligonucleotide, CCAAT/enhancer-binding protein beta | Authors: | Horton, J.R, Cheng, X, Yang, J. | Deposit date: | 2018-09-12 | Release date: | 2018-12-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for effects of CpA modifications on C/EBP beta binding of DNA. Nucleic Acids Res., 47, 2019
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