4M78
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![BU of 4m78 by Molmil](/molmil-images/mine/4m78) | Crystal structure of Lsm2-8 complex, space group P21 | Descriptor: | U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, U6 snRNA-associated Sm-like protein LSm4, ... | Authors: | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | Deposit date: | 2013-08-12 | Release date: | 2013-11-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.794 Å) | Cite: | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature, 506, 2014
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4AYW
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![BU of 4ayw by Molmil](/molmil-images/mine/4ayw) | STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (PLATE FORM) | Descriptor: | ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, CHOLESTEROL HEMISUCCINATE, DODECYL-BETA-D-MALTOSIDE, ... | Authors: | Pike, A.C.W, Shintre, C.A, Li, Q, Kim, J, von Delft, F, Barr, A.J, Das, S, Chaikuad, A, Xia, X, Quigley, A, Dong, Y, Dong, L, Krojer, T, Vollmar, M, Muniz, J.R.C, Bray, J.E, Berridge, G, Chalk, R, Gileadi, O, Burgess-Brown, N, Shrestha, L, Goubin, S, Yang, J, Mahajan, P, Mukhopadhyay, S, Bullock, A.N, Arrowsmith, C.H, Weigelt, J, Bountra, C, Edwards, A.M, Carpenter, E.P. | Deposit date: | 2012-06-22 | Release date: | 2012-07-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States Proc.Natl.Acad.Sci.USA, 110, 2013
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2JYJ
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![BU of 2jyj by Molmil](/molmil-images/mine/2jyj) | Re-refining the tetraloop-receptor RNA-RNA complex using NMR-derived restraints and Xplor-nih (2.18) | Descriptor: | RNA (43-MER) | Authors: | Zuo, X, Wang, J, Foster, T.R, Schwieters, C.D, Tiede, D.M, Butcher, S.E, Wang, Y. | Deposit date: | 2007-12-13 | Release date: | 2008-10-07 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | RNA helical packing in solution: NMR structure of a 30 kDa GAAA tetraloop-receptor complex. J.Mol.Biol., 351, 2005
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2JZ3
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![BU of 2jz3 by Molmil](/molmil-images/mine/2jz3) | SOCS box elonginBC ternary complex | Descriptor: | Suppressor of cytokine signaling 3, Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2 | Authors: | Babon, J.J, Sabo, J, Soetopo, A, Yao, S, Bailey, M.F, Zhang, J, Nicola, N.A, Norton, R.S. | Deposit date: | 2007-12-27 | Release date: | 2008-09-23 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The SOCS box domain of SOCS3: structure and interaction with the elonginBC-cullin5 ubiquitin ligase J.Mol.Biol., 381, 2008
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4AW6
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![BU of 4aw6 by Molmil](/molmil-images/mine/4aw6) | Crystal structure of the human nuclear membrane zinc metalloprotease ZMPSTE24 (FACE1) | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CAAX PRENYL PROTEASE 1 HOMOLOG, ZINC ION | Authors: | Pike, A.C.W, Dong, Y.Y, Quigley, A, Dong, L, Cooper, C.D.O, Chaikuad, A, Goubin, S, Shrestha, L, Li, Q, Mukhopadhyay, S, Yang, J, Xia, X, Shintre, C.A, Barr, A.J, Berridge, G, Chalk, R, Bray, J.E, von Delft, F, Bullock, A, Bountra, C, Arrowsmith, C.H, Edwards, A, Burgess-Brown, N, Carpenter, E.P. | Deposit date: | 2012-05-31 | Release date: | 2012-07-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | The Structural Basis of Zmpste24-Dependent Laminopathies. Science, 339, 2013
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4R05
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![BU of 4r05 by Molmil](/molmil-images/mine/4r05) | Crystal structure of the refolded DENV3 methyltransferase | Descriptor: | Nonstructural protein NS5 | Authors: | Brecher, M.B, Li, Z, Zhang, J, Chen, H, Lin, Q, Liu, B, Li, H.M. | Deposit date: | 2014-07-29 | Release date: | 2014-11-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase. Protein Sci., 24, 2015
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1Z7I
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3IZX
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![BU of 3izx by Molmil](/molmil-images/mine/3izx) | 3.1 Angstrom cryoEM structure of cytoplasmic polyhedrosis virus | Descriptor: | Capsid protein VP1, Structural protein VP3, Viral structural protein 5 | Authors: | Yu, X, Ge, P, Jiang, J, Atanasov, I, Zhou, Z.H. | Deposit date: | 2011-01-15 | Release date: | 2011-06-22 | Last modified: | 2018-08-22 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Atomic Model of CPV Reveals the Mechanism Used by This Single-Shelled Virus to Economically Carry Out Functions Conserved in Multishelled Reoviruses. Structure, 19, 2011
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2GIB
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![BU of 2gib by Molmil](/molmil-images/mine/2gib) | Crystal structure of the SARS coronavirus nucleocapsid protein dimerization domain | Descriptor: | Nucleocapsid protein, SULFATE ION | Authors: | Yu, I.M, Oldham, M.L, Zhang, J, Chen, J. | Deposit date: | 2006-03-28 | Release date: | 2006-04-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of the severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein dimerization domain reveals evolutionary linkage between corona- and arteriviridae. J.Biol.Chem., 281, 2006
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2LAG
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![BU of 2lag by Molmil](/molmil-images/mine/2lag) | Structure of the 44 kDa complex of interferon-alpha2 with the extracellular part of IFNAR2 obtained by 2D-double difference NOESY | Descriptor: | Interferon alpha-2, Interferon alpha/beta receptor 2 | Authors: | Nudelman, I, Akabayov, S.R, Scherf, T, Anglister, J. | Deposit date: | 2011-03-13 | Release date: | 2011-08-17 | Last modified: | 2011-09-28 | Method: | SOLUTION NMR | Cite: | Observation of Intermolecular Interactions in Large Protein Complexes by 2D-Double Difference Nuclear Overhauser Enhancement Spectroscopy: Application to the 44 kDa Interferon-Receptor Complex. J.Am.Chem.Soc., 133, 2011
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3WUZ
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![BU of 3wuz by Molmil](/molmil-images/mine/3wuz) | Crystal structure of the Ig V-set domain of human paired immunoglobulin-like type 2 receptor alpha | Descriptor: | CITRIC ACID, ISOPROPYL ALCOHOL, Paired immunoglobulin-like type 2 receptor alpha | Authors: | Kuroki, K, Wang, J, Ose, T, Yamaguchi, M, Tabata, S, Maita, N, Nakamura, S, Kajikawa, M, Kogure, A, Satoh, T, Arase, H, Maenaka, K. | Deposit date: | 2014-05-10 | Release date: | 2014-06-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structural basis for simultaneous recognition of an O-glycan and its attached peptide of mucin family by immune receptor PILR alpha Proc.Natl.Acad.Sci.USA, 111, 2014
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4DG3
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2H60
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![BU of 2h60 by Molmil](/molmil-images/mine/2h60) | Solution Structure of Human Brg1 Bromodomain | Descriptor: | Probable global transcription activator SNF2L4 | Authors: | Shen, W, Xu, C, Zhang, J, Wu, J, Shi, Y. | Deposit date: | 2006-05-30 | Release date: | 2007-02-13 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of human Brg1 bromodomain and its specific binding to acetylated histone tails Biochemistry, 46, 2007
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4DK5
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![BU of 4dk5 by Molmil](/molmil-images/mine/4dk5) | Crystal structure of human PI3K-gamma in complex with a pyridyl-triazine inhibitor | Descriptor: | 4-(2-[(6-methoxypyridin-3-yl)amino]-5-{[4-(methylsulfonyl)piperazin-1-yl]methyl}pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION | Authors: | Whittington, D.A, Tang, J, Yakowec, P. | Deposit date: | 2012-02-03 | Release date: | 2012-05-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structure-based design of a novel series of potent, selective inhibitors of the class I phosphatidylinositol 3-kinases. J.Med.Chem., 55, 2012
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1V9P
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![BU of 1v9p by Molmil](/molmil-images/mine/1v9p) | Crystal Structure Of Nad+-Dependent DNA Ligase | Descriptor: | ADENOSINE MONOPHOSPHATE, DNA ligase, ZINC ION | Authors: | Lee, J.Y, Chang, C, Song, H.K, Moon, J, Yang, J.K, Kim, H.K, Kwon, S.K, Suh, S.W. | Deposit date: | 2004-01-27 | Release date: | 2004-03-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of NAD(+)-dependent DNA ligase: modular architecture and functional implications. Embo J., 19, 2000
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2JXN
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![BU of 2jxn by Molmil](/molmil-images/mine/2jxn) | Solution Structure of S. cerevisiae PDCD5-like Protein Ymr074cp | Descriptor: | S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, Uncharacterized protein YMR074C | Authors: | Hong, J, Zhang, J, Liu, Z, Shi, Y, Wu, J. | Deposit date: | 2007-11-23 | Release date: | 2008-12-02 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | Solution Structure and Dynamics of S. cerevisiae PDCD5-like Protein Ymr074cp Determined by Heteronuclear NMR Spectroscopy To be Published
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3S2A
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![BU of 3s2a by Molmil](/molmil-images/mine/3s2a) | Crystal structure of PI3K-gamma in complex with a quinoline inhibitor | Descriptor: | N-{2-chloro-5-[4-(morpholin-4-yl)quinolin-6-yl]pyridin-3-yl}-4-fluorobenzenesulfonamide, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION | Authors: | Whittington, D.A, Tang, J, Yakowec, P. | Deposit date: | 2011-05-16 | Release date: | 2011-06-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Phospshoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors: Discovery and Structure-Activity Relationships of a Series of Quinoline and Quinoxaline Derivatives. J.Med.Chem., 54, 2011
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3C1P
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![BU of 3c1p by Molmil](/molmil-images/mine/3c1p) | Crystal Structure of an alternating D-Alanyl, L-Homoalanyl PNA | Descriptor: | Peptide Nucleic Acid DLY-HGL-AGD-LHC-AGD-LHC-CUD-LYS | Authors: | Cuesta-Seijo, J.A, Sheldrick, G.M, Zhang, J, Diederichsen, U. | Deposit date: | 2008-01-23 | Release date: | 2009-01-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Continuous beta-turn fold of an alternating alanyl/homoalanyl peptide nucleic acid. Acta Crystallogr.,Sect.D, 68, 2012
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2JPS
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![BU of 2jps by Molmil](/molmil-images/mine/2jps) | NAB2 N-terminal domain | Descriptor: | Nuclear polyadenylated RNA-binding protein NAB2 | Authors: | Grant, R, Marshall, N.J, Yang, J, Fasken, M, Kelly, S, Harreman, M.T, Neuhaus, D, Corbett, A.H, Stewart, M. | Deposit date: | 2007-05-23 | Release date: | 2008-03-18 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Structure of the N-terminal Mlp1-binding domain of the Saccharomyces cerevisiae mRNA-binding protein, Nab2 J.Mol.Biol., 376, 2008
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7EY3
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![BU of 7ey3 by Molmil](/molmil-images/mine/7ey3) | Double cysteine mutations in T1 lipase | Descriptor: | CALCIUM ION, CHLORIDE ION, SODIUM ION, ... | Authors: | Hamdan, S.H, Leow, T.C, Yahaya, N.M, Ali, M.S.M, Jonet, M.A, Mohamad Aris, S.N.A, Maiangwa, J. | Deposit date: | 2021-05-29 | Release date: | 2022-12-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Knotting terminal ends of mutant T1 lipase with disulfide bond improved structure rigidity and stability. Appl.Microbiol.Biotechnol., 107, 2023
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2FG5
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![BU of 2fg5 by Molmil](/molmil-images/mine/2fg5) | Crystal structure of human RAB31 in complex with a GTP analogue | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-31 | Authors: | Tempel, W, Wang, J, Ismail, S, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2005-12-21 | Release date: | 2006-01-10 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Crystal structure of human RAB31 in complex with a GTP analogue To be Published
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1IH7
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![BU of 1ih7 by Molmil](/molmil-images/mine/1ih7) | High-Resolution Structure of Apo RB69 DNA Polymerase | Descriptor: | DNA POLYMERASE, GUANOSINE, POTASSIUM ION | Authors: | Franklin, M.C, Wang, J, Steitz, T.A. | Deposit date: | 2001-04-18 | Release date: | 2001-06-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Structure of the Replicating Complex of a Pol alpha Family DNA Polymerase Cell(Cambridge,Mass.), 105, 2001
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1L4D
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![BU of 1l4d by Molmil](/molmil-images/mine/1l4d) | CRYSTAL STRUCTURE OF MICROPLASMINOGEN-STREPTOKINASE ALPHA DOMAIN COMPLEX | Descriptor: | PLASMINOGEN, STREPTOKINASE, SULFATE ION | Authors: | Wakeham, N, Terzyan, S, Zhai, P, Loy, J.A, Tang, J, Zhang, X.C. | Deposit date: | 2002-03-04 | Release date: | 2002-12-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Effects of deletion of streptokinase residues 48-59 on plasminogen activation PROTEIN ENG., 15, 2002
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1L3K
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![BU of 1l3k by Molmil](/molmil-images/mine/1l3k) | UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1 | Descriptor: | HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 | Authors: | Vitali, J, Ding, J, Jiang, J, Zhang, Y, Krainer, A.R, Xu, R.-M. | Deposit date: | 2002-02-27 | Release date: | 2002-04-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Correlated alternative side chain conformations in the RNA-recognition motif of heterogeneous nuclear ribonucleoprotein A1. Nucleic Acids Res., 30, 2002
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2LUN
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![BU of 2lun by Molmil](/molmil-images/mine/2lun) | |