6OVG
 
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6OII
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6OMW
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6OPB
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4QLA
 | | Crystal structure of juvenile hormone epoxide hydrolase from the silkworm Bombyx mori | | 分子名称: | Juvenile hormone epoxide hydrolase, PENTAETHYLENE GLYCOL | | 著者 | Zhou, K, Jia, N, Hu, C, Jiang, Y.L, Yang, J.P, Chen, Y, Li, S, Zhou, C.Z. | | 登録日 | 2014-06-11 | | 公開日 | 2014-09-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of juvenile hormone epoxide hydrolase from the silkworm Bombyx mori.
Proteins, 82, 2014
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7V40
 | | Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 | | 分子名称: | PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, p450tol monooxygenase | | 著者 | Zhang, L.L, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2021-08-12 | | 公開日 | 2022-06-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity
Acs Catalysis, 12, 2022
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7V42
 | | Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 in complex with benzyl-alcohol. | | 分子名称: | PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, p450tol monooxygenase, ... | | 著者 | Zhang, L.L, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2021-08-12 | | 公開日 | 2022-06-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity
Acs Catalysis, 12, 2022
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6PMO
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8DGB
 | | Crystal Structure of SARS-CoV-2 Main Protease (Mpro) Q192T Mutant in Complex with Inhibitor GC376 | | 分子名称: | (1R,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase nsp5 | | 著者 | Lewandowski, E.M, Jacobs, L.M.C, Hu, Y, Tan, H, Wang, J, Chen, Y. | | 登録日 | 2022-06-23 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | | 主引用文献 | Naturally Occurring Mutations of SARS-CoV-2 Main Protease Confer Drug Resistance to Nirmatrelvir.
Acs Cent.Sci., 9, 2023
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8DD1
 | | SARS-CoV-2 Main Protease (Mpro) H164N Mutant in Complex with Inhibitor GC376 | | 分子名称: | (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase nsp5 | | 著者 | Lewandowski, E.M, Butler, S.G, Hu, Y, Tan, H, Wang, J, Chen, Y. | | 登録日 | 2022-06-17 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Naturally Occurring Mutations of SARS-CoV-2 Main Protease Confer Drug Resistance to Nirmatrelvir.
Acs Cent.Sci., 9, 2023
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8DFN
 | | Crystal Structure of SARS-CoV-2 Main Protease (Mpro) H164N Mutant | | 分子名称: | 3C-like proteinase nsp5 | | 著者 | Lewandowski, E.M, Butler, S.G, Hu, Y, Tan, H, Wang, J, Chen, Y. | | 登録日 | 2022-06-22 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Naturally Occurring Mutations of SARS-CoV-2 Main Protease Confer Drug Resistance to Nirmatrelvir.
Acs Cent.Sci., 9, 2023
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8DCZ
 | | Crystal Structure of SARS-CoV-2 Main Protease (Mpro) M165Y Mutant in Complex with Nirmatrelvir | | 分子名称: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | | 著者 | Lewandowski, E.M, Hu, Y, Tan, H, Wang, J, Chen, Y. | | 登録日 | 2022-06-17 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Naturally Occurring Mutations of SARS-CoV-2 Main Protease Confer Drug Resistance to Nirmatrelvir.
Acs Cent.Sci., 9, 2023
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4M9Y
 | | Crystal structure of CED-4 bound CED-3 fragment | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CED-3 fragment, Cell death protein 4, ... | | 著者 | Huang, W.J, Jinag, T.Y, Choi, W.Y, Wang, J.W, Shi, Y.G. | | 登録日 | 2013-08-15 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | Mechanistic insights into CED-4-mediated activation of CED-3.
Genes Dev., 27, 2013
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7N17
 | | Structure of TAX-4_R421W apo open state | | 分子名称: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel | | 著者 | Zheng, X, Li, H, Hu, Z, Su, D, Yang, J. | | 登録日 | 2021-05-27 | | 公開日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel.
Commun Biol, 5, 2022
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7N15
 | | Structure of TAX-4_R421W w/cGMP open state | | 分子名称: | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CYCLIC GUANOSINE MONOPHOSPHATE, ... | | 著者 | Zheng, X, Li, H, Hu, Z, Su, D, Yang, J. | | 登録日 | 2021-05-27 | | 公開日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel.
Commun Biol, 5, 2022
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7N16
 | | Structure of TAX-4_R421W apo closed state | | 分子名称: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel, SODIUM ION | | 著者 | Zheng, X, Li, H, Hu, Z, Su, D, Yang, J. | | 登録日 | 2021-05-27 | | 公開日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel.
Commun Biol, 5, 2022
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6P3Q
 | | Calpain-5 (CAPN5) Protease Core (PC) | | 分子名称: | Calpain-5 | | 著者 | Velez, G, Sun, Y.J, Khan, S, Yang, J, Koster, H.J, Lokesh, G, Mahajan, V. | | 登録日 | 2019-05-24 | | 公開日 | 2020-02-05 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Insights into the Unique Activation Mechanisms of a Non-classical Calpain and Its Disease-Causing Variants.
Cell Rep, 30, 2020
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7EBJ
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4M9Z
 | | Crystal structure of CED-4 bound CED-3 fragment | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CED-3 fragment, Cell death protein 4, ... | | 著者 | Huang, W.J, Jinag, T.Y, Choi, W.Y, Wang, J.W, Shi, Y.G. | | 登録日 | 2013-08-15 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (3.405 Å) | | 主引用文献 | Mechanistic insights into CED-4-mediated activation of CED-3.
Genes Dev., 27, 2013
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3MQC
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7W5S
 | | A nonheme iron- and alpha-ketoglutarate- dependent halogenase that catalyzes nucleotide substrates | | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FE (II) ION, ... | | 著者 | Dai, L.H, Zhang, X, Hu, Y.M, Huang, J.W, Chen, C.C, Guo, R.T. | | 登録日 | 2021-11-30 | | 公開日 | 2022-04-13 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Structural and Functional Insights into a Nonheme Iron- and alpha-Ketoglutarate-Dependent Halogenase That Catalyzes Chlorination of Nucleotide Substrates.
Appl.Environ.Microbiol., 88, 2022
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7W5T
 | | A nonheme iron- and alpha-ketoglutarate- dependent halogenase that catalyzes nucleotide substrates | | 分子名称: | 2-OXOGLUTARIC ACID, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Dai, L.H, Zhang, X, Hu, Y.M, Huang, J.W, Chen, C.C, Guo, R.T. | | 登録日 | 2021-11-30 | | 公開日 | 2022-04-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Structural and Functional Insights into a Nonheme Iron- and alpha-Ketoglutarate-Dependent Halogenase That Catalyzes Chlorination of Nucleotide Substrates.
Appl.Environ.Microbiol., 88, 2022
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4IFT
 | | Crystal structure of double mutant thermostable NPPase from Geobacillus stearothermophilus | | 分子名称: | Thermostable NPPase | | 著者 | Guo, Z, Huang, J, Wang, F, Qiu, R, Wang, Y, Ji, C. | | 登録日 | 2012-12-15 | | 公開日 | 2013-12-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.995 Å) | | 主引用文献 | Crystal structure of thermostable NPPase from Geobacillus stearothermophilus
To be Published
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7W5V
 | | A nonheme iron- and alpha-ketoglutarate- dependent halogenase that catalyzes nucleotide substrates | | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FE (III) ION, ... | | 著者 | Dai, L.H, Zhang, X, Hu, Y.M, Huang, J.W, Chen, C.C, Guo, R.T. | | 登録日 | 2021-11-30 | | 公開日 | 2022-04-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Structural and Functional Insights into a Nonheme Iron- and alpha-Ketoglutarate-Dependent Halogenase That Catalyzes Chlorination of Nucleotide Substrates.
Appl.Environ.Microbiol., 88, 2022
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4GIF
 | | C-terminal coiled-coil domain of transient receptor potential channel TRPP3 (PKD2L1, Polycystin-L) | | 分子名称: | Polycystic kidney disease 2-like 1 protein | | 著者 | Yu, Y, Ulbrich, M.H, Li, M.-H, Dobbins, S, Zhang, W.K, Tong, L, Isacoff, E.Y, Yang, J. | | 登録日 | 2012-08-08 | | 公開日 | 2012-12-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Molecular mechanism of the assembly of an acid-sensing receptor ion channel complex.
Nat Commun, 3, 2012
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