5ZZ8
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![BU of 5zz8 by Molmil](/molmil-images/mine/5zz8) | Structure of the Herpes simplex virus type 2 C-capsid with capsid-vertex-specific component | 分子名称: | Major capsid protein, UL17, UL25, ... | 著者 | Wang, J.L, Yuan, S, Zhu, D.J, Tang, H, Wang, N, Chen, W.Y, Gao, Q, Li, Y.H, Wang, J.Z, Liu, H.R, Zhang, X.Z, Rao, Z.H, Wang, X.X. | 登録日 | 2018-05-31 | 公開日 | 2018-10-10 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | 主引用文献 | Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component. Nat Commun, 9, 2018
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6LYW
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![BU of 6lyw by Molmil](/molmil-images/mine/6lyw) | Structural insight into the biological functions of Arabidopsis thaliana ACHT1 | 分子名称: | GLYCEROL, SULFATE ION, Thioredoxin-like 2-1, ... | 著者 | Wang, J.C, Pan, W.M, Wang, M.Z, Zhang, M. | 登録日 | 2020-02-16 | 公開日 | 2020-05-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural insight into the biological functions of Arabidopsis thaliana ACHT1. Int.J.Biol.Macromol., 158, 2020
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4ZK4
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![BU of 4zk4 by Molmil](/molmil-images/mine/4zk4) | Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with 7-(5-isopropoxy-pyridin-3-yl)-1-methyl-1,7-diaza-spiro[4.4]nonane | 分子名称: | (5R)-1-methyl-7-[5-(propan-2-yloxy)pyridin-3-yl]-1,7-diazaspiro[4.4]nonane, MAGNESIUM ION, SULFATE ION, ... | 著者 | Bobango, J, Wu, J, Talley, T.T. | 登録日 | 2015-04-29 | 公開日 | 2015-05-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with 7-(5-isopropoxy-pyridin-3-yl)-1-methyl-1,7-diaza-spiro[4.4]nonane. To be Published
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6LYX
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![BU of 6lyx by Molmil](/molmil-images/mine/6lyx) | Crystal structure of oxidized ACHT1 | 分子名称: | GLYCEROL, SULFATE ION, Thioredoxin-like 2-1, ... | 著者 | Wang, J.C, Pan, W.M, Cai, W.G, Wang, M.Z, Zhang, M. | 登録日 | 2020-02-16 | 公開日 | 2020-05-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | 主引用文献 | Structural insight into the biological functions of Arabidopsis thaliana ACHT1. Int.J.Biol.Macromol., 158, 2020
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4ZRU
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![BU of 4zru by Molmil](/molmil-images/mine/4zru) | X-ray crystal structure of Lymnaea stagnalis acetylcholine binding protein (Ls-AChBP) in complex with 3-[2-[(2S)-pyrrolidin-2-yl]ethynyl]pyridine (TI-5180) | 分子名称: | 3-[(2S)-pyrrolidin-2-ylethynyl]pyridine, Acetylcholine-binding protein, PHOSPHATE ION | 著者 | Bobango, J, Sankaran, B, Park, J.F, Wu, J, Talley, T.T. | 登録日 | 2015-05-12 | 公開日 | 2015-05-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Comparisons of Binding Affinities for Neuronal Nicotinic Receptors (NNRs) and AChBPs, and Structural Features of a High-Affinity, Non-selective NNR Ligand-AChBP Co-crystal Structure To be Published
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6VSJ
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![BU of 6vsj by Molmil](/molmil-images/mine/6vsj) | Cryo-electron microscopy structure of mouse coronavirus spike protein complexed with its murine receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Carcinoembryonic antigen-related cell adhesion molecule 1, Spike glycoprotein | 著者 | Shang, J, Wan, Y.S, Liu, C, Yount, B, Gully, K, Yang, Y, Auerbach, A, Peng, G.Q, Baric, R, Li, F. | 登録日 | 2020-02-11 | 公開日 | 2020-03-04 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.94 Å) | 主引用文献 | Structure of mouse coronavirus spike protein complexed with receptor reveals mechanism for viral entry. Plos Pathog., 16, 2020
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4ZR6
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![BU of 4zr6 by Molmil](/molmil-images/mine/4zr6) | Lymnaea Stagnalis Acetylcholine Binding Protein in Complex with 3-[(4E)-4-[(3-methylimidazol-4-yl)methylene]-2,3-dihydropyrrol-5-yl]pyridine | 分子名称: | 3-{(4E)-4-[(1-methyl-1H-imidazol-5-yl)methylidene]-3,4-dihydro-2H-pyrrol-5-yl}pyridine, Acetylcholine-binding protein | 著者 | Bobango, J, Bryant, D, Denton, T.T, Talley, T.T. | 登録日 | 2015-05-11 | 公開日 | 2016-05-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-guided design and analysis of arylidene anabaseines and myosmines To be Published
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8HPM
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![BU of 8hpm by Molmil](/molmil-images/mine/8hpm) | LpqY-SugABC in state 2 | 分子名称: | ABC sugar transporter, permease component, ABC transporter, ... | 著者 | Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F. | 登録日 | 2022-12-12 | 公開日 | 2023-09-06 | 最終更新日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (3.82 Å) | 主引用文献 | Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC. Structure, 31, 2023
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8HPN
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![BU of 8hpn by Molmil](/molmil-images/mine/8hpn) | LpqY-SugABC in state 3 | 分子名称: | ABC sugar transporter, permease component, ABC transporter, ... | 著者 | Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F. | 登録日 | 2022-12-12 | 公開日 | 2023-09-06 | 最終更新日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (4.55 Å) | 主引用文献 | Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC. Structure, 31, 2023
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8HPS
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![BU of 8hps by Molmil](/molmil-images/mine/8hps) | LpqY-SugABC in state 5 | 分子名称: | ABC sugar transporter, permease component, ABC transporter, ... | 著者 | Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F. | 登録日 | 2022-12-12 | 公開日 | 2023-09-06 | 最終更新日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (3.51 Å) | 主引用文献 | Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC. Structure, 31, 2023
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8HPL
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![BU of 8hpl by Molmil](/molmil-images/mine/8hpl) | LpqY-SugABC in state 1 | 分子名称: | ABC sugar transporter, permease component, ABC transporter, ... | 著者 | Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F. | 登録日 | 2022-12-12 | 公開日 | 2023-09-06 | 最終更新日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (4.29 Å) | 主引用文献 | Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC. Structure, 31, 2023
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8HPR
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![BU of 8hpr by Molmil](/molmil-images/mine/8hpr) | LpqY-SugABC in state 4 | 分子名称: | ABC sugar transporter, permease component, ABC transporter, ... | 著者 | Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F. | 登録日 | 2022-12-12 | 公開日 | 2023-09-06 | 最終更新日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | 主引用文献 | Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC. Structure, 31, 2023
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5Z9Y
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![BU of 5z9y by Molmil](/molmil-images/mine/5z9y) | Crystal structure of Mycobacterium tuberculosis thiazole synthase (ThiG) complexed with DXP | 分子名称: | 1-DEOXY-D-XYLULOSE-5-PHOSPHATE, Thiazole synthase | 著者 | Zhang, J, Zhang, B, Zhao, Y, Yang, X, Huang, M, Cui, P, Zhang, W, Li, J, Zhang, Y. | 登録日 | 2018-02-05 | 公開日 | 2018-04-11 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Snapshots of catalysis: Structure of covalently bound substrate trapped in Mycobacterium tuberculosis thiazole synthase (ThiG). Biochem. Biophys. Res. Commun., 497, 2018
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6M12
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![BU of 6m12 by Molmil](/molmil-images/mine/6m12) | Crystal Structure of Rnase L in complex with SU11652 | 分子名称: | 5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE, PHOSPHATE ION, Ribonuclease L, ... | 著者 | Tang, J, Huang, H. | 登録日 | 2020-02-24 | 公開日 | 2020-09-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Sunitinib inhibits RNase L by destabilizing its active dimer conformation. Biochem.J., 477, 2020
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8K75
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![BU of 8k75 by Molmil](/molmil-images/mine/8k75) | |
8E15
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![BU of 8e15 by Molmil](/molmil-images/mine/8e15) | A computationally stabilized hMPV F protein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F1 protein with Fibritin peptide, F2 protein, ... | 著者 | Huang, J, Gonzalez, K, Mousa, J, Strauch, E. | 登録日 | 2022-08-09 | 公開日 | 2023-04-12 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | A general computational design strategy for stabilizing viral class I fusion proteins. Nat Commun, 15, 2024
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6M13
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![BU of 6m13 by Molmil](/molmil-images/mine/6m13) | Crystal structure of Rnase L in complex with Toceranib | 分子名称: | 5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-(2-pyrrolidin-1-ylethyl)-1H-pyrrole-3-carboxamide, PHOSPHATE ION, Ribonuclease L, ... | 著者 | Tang, J, Huang, H. | 登録日 | 2020-02-24 | 公開日 | 2020-09-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Sunitinib inhibits RNase L by destabilizing its active dimer conformation. Biochem.J., 477, 2020
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6B7N
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![BU of 6b7n by Molmil](/molmil-images/mine/6b7n) | Cryo-electron microscopy structure of porcine delta coronavirus spike protein in the pre-fusion state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Shang, J, Zheng, Y, Yang, Y, Liu, C, Geng, Q, Tai, W, Du, L, Zhou, Y, Zhang, W, Li, F. | 登録日 | 2017-10-04 | 公開日 | 2017-10-25 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-Electron Microscopy Structure of Porcine Deltacoronavirus Spike Protein in the Prefusion State J. Virol., 92, 2018
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4L2Y
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![BU of 4l2y by Molmil](/molmil-images/mine/4l2y) | Crystal Structure of p110alpha complexed with niSH2 of p85alpha and compound 9d | 分子名称: | 3-amino-5-[4-(morpholin-4-yl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol, GLYCEROL, Phosphatidylinositol 3-kinase regulatory subunit alpha, ... | 著者 | Zhang, J, Zhao, Y.L, Chen, Y.Y, Huang, M, Jiang, F. | 登録日 | 2013-06-05 | 公開日 | 2014-01-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structures of PI3K alpha Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design. ACS Med Chem Lett, 5, 2014
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4L1B
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![BU of 4l1b by Molmil](/molmil-images/mine/4l1b) | Crystal Structure of p110alpha complexed with niSH2 of p85alpha | 分子名称: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, SULFATE ION | 著者 | Zhang, J, Zhao, Y.L, Chen, Y.Y, Huang, M, Jiang, F. | 登録日 | 2013-06-03 | 公開日 | 2014-01-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.586 Å) | 主引用文献 | Crystal Structures of PI3K alpha Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design. ACS Med Chem Lett, 5, 2014
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4XNR
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![BU of 4xnr by Molmil](/molmil-images/mine/4xnr) | Vibrio Vulnificus Adenine Riboswitch Aptamer Domain, Synthesized by Position-selective Labeling of RNA (PLOR), in Complex with Adenine | 分子名称: | ADENINE, MAGNESIUM ION, Vibrio Vulnificus Adenine Riboswitch | 著者 | Zhang, J, Liu, Y, Wang, Y.-X, Ferre-D'Amare, A.R. | 登録日 | 2015-01-16 | 公開日 | 2015-05-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Synthesis and applications of RNAs with position-selective labelling and mosaic composition. Nature, 522, 2015
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8EHI
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![BU of 8ehi by Molmil](/molmil-images/mine/8ehi) | Cryo-EM structure of his-elemental paused elongation complex with an unfolded TL (2) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | 登録日 | 2022-09-14 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EHF
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![BU of 8ehf by Molmil](/molmil-images/mine/8ehf) | Cryo-EM structure of his-elemental paused elongation complex with an unfolded TL (1) | 分子名称: | (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | 登録日 | 2022-09-14 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EG8
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![BU of 8eg8 by Molmil](/molmil-images/mine/8eg8) | Cryo-EM structure of consensus elemental paused elongation complex with a folded TL | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | 登録日 | 2022-09-12 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EHA
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![BU of 8eha by Molmil](/molmil-images/mine/8eha) | Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (out) | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | 登録日 | 2022-09-14 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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