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PDB: 4046 件

5JR9
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Crystal structure of apo-NeC3PO
分子名称: NEQ131
著者Zhang, J, Gan, J.
登録日2016-05-06
公開日2016-09-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for single-stranded RNA recognition and cleavage by C3PO
Nucleic Acids Res., 44, 2016
6KIX
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Cryo-EM structure of human MLL1-NCP complex, binding mode1
分子名称: DNA (145-MER), GLUTAMINE, Histone H2A, ...
著者Huang, J, Xue, H, Yao, T.
登録日2019-07-20
公開日2019-09-11
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
6KIV
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Cryo-EM structure of human MLL1-ubNCP complex (4.0 angstrom)
分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
著者Huang, J, Xue, H, Yao, T.
登録日2019-07-20
公開日2019-09-11
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
6KIZ
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Cryo-EM structure of human MLL1-NCP complex, binding mode2
分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
著者Huang, J, Xue, H, Yao, T.
登録日2019-07-20
公開日2019-09-11
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
5ZNM
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Colicin D Central Domain and C-terminal tRNase domain
分子名称: Colicin-D, GLYCEROL, SULFATE ION
著者Chang, J.W, Sato, Y, Ogawa, T, Arakawa, T, Fukai, S, Fushinobu, S, Masaki, H.
登録日2018-04-10
公開日2018-08-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of the central and the C-terminal RNase domains of colicin D implicated its translocation pathway through inner membrane of target cell
J. Biochem., 164, 2018
4WHK
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A New Class of Peptidomimetics Targeting the Polo-box Domain of Polo-like kinase 1
分子名称: C6H5(CH2)8-DERIVATIZED PEPTIDE INHIBITOR, Serine/threonine-protein kinase PLK1
著者Bang, J.K, Han, Y.H, Ahn, M.J, Lee, K.S.
登録日2014-09-23
公開日2014-12-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A new class of peptidomimetics targeting the polo-box domain of polo-like kinase 1.
J.Med.Chem., 58, 2015
7CBB
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Crystal structure of SbnC in the biosynthesis of staphyloferrin B
分子名称: ADENOSINE MONOPHOSPHATE, IucA/IucC family siderophore biosynthesis protein
著者Tang, J, Ju, Y, Zhou, H.
登録日2020-06-11
公開日2020-09-23
最終更新日2020-10-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and Biochemical Characterization of SbnC as a Representative Type B Siderophore Synthetase.
Acs Chem.Biol., 15, 2020
4WHL
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A New Class of Peptidomimetics Targeting the Polo-box Domain of Polo-like kinase 1
分子名称: C6H5(CH2)8-DERIVATIZED PEPTIDE INHIBITOR, Serine/threonine-protein kinase PLK1
著者Bang, J.K, Han, Y.H, Ahn, M.J, Lee, K.S.
登録日2014-09-23
公開日2014-12-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献A new class of peptidomimetics targeting the polo-box domain of polo-like kinase 1.
J.Med.Chem., 58, 2015
5ZX5
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3.3 angstrom structure of mouse TRPM7 with EDTA
分子名称: CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily M member 7
著者Zhang, J, Li, Z, Duan, J, Li, J, Hulse, R.E, Santa-Cruz, A, Abiria, S.A, Krapivinsky, G, Clapham, D.E.
登録日2018-05-18
公開日2018-10-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Structure of the mammalian TRPM7, a magnesium channel required during embryonic development.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4WHH
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A New Class of Peptidomimetics Targeting the Polo-box Domain of Polo-like kinase 1
分子名称: C6H5(CH2)8-DERIVATIZED PEPTIDE INHIBITOR, SULFATE ION, Serine/threonine-protein kinase PLK1
著者Bang, J.K.
登録日2014-09-22
公開日2014-12-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A new class of peptidomimetics targeting the polo-box domain of polo-like kinase 1.
J.Med.Chem., 58, 2015
5HM2
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Crystal structure of the 3C protease from South African Territories type 2 foot-and-mouth disease virus
分子名称: 3C proteinase
著者Yang, J, Leen, E.N, Curry, S.
登録日2016-01-15
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the 3C protease from Southern African Territories type 2 foot-and-mouth disease virus.
Peerj, 4, 2016
7V69
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Cryo-EM structure of a class A GPCR-G protein complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Wang, J.J, Wu, M, Wu, L.J, Hua, T, Liu, Z.J, Wang, T.
登録日2021-08-20
公開日2022-05-11
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献The unconventional activation of the muscarinic acetylcholine receptor M4R by diverse ligands.
Nat Commun, 13, 2022
7V6A
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Cry-EM structure of M4-c110-G protein complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Wang, J.J, Wu, M, Wu, L.J, Hua, T, Liu, Z.J, Wang, T.
登録日2021-08-20
公開日2022-05-11
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献The unconventional activation of the muscarinic acetylcholine receptor M4R by diverse ligands.
Nat Commun, 13, 2022
7V68
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An Agonist and PAM-bound Class A GPCR with Gi protein complex structure
分子名称: 3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy]thieno[2,3-b]pyridine-2-carboxamide, 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Wang, J.J, Wu, L.J, Wu, M, Hua, T, Liu, Z.J, Wang, T.
登録日2021-08-20
公開日2022-05-11
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献The unconventional activation of the muscarinic acetylcholine receptor M4R by diverse ligands.
Nat Commun, 13, 2022
8CI0
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Maize Transketolase in complex with TPP and hydrolyzed (+)-Cornexistin
分子名称: (1~{Z},3~{R},4~{S},7~{S},8~{Z})-8-ethylidene-4,7-bis(oxidanyl)-5-oxidanylidene-3-propyl-cyclononene-1,2-dicarboxylic acid, 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2H-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, MAGNESIUM ION, ...
著者Freigang, J.
登録日2023-02-08
公開日2023-03-22
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献Investigations into Simplified Analogues of the Herbicidal Natural Product (+)-Cornexistin.
Chemistry, 29, 2023
6O67
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Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Mitoglitazone
分子名称: Mitoglitazone, Peroxisome proliferator-activated receptor gamma, nonanoic acid
著者Shang, J, Kojetin, D.J.
登録日2019-03-05
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Quantitative structural assessment of graded receptor agonism.
Proc.Natl.Acad.Sci.USA, 116, 2019
6O68
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Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Ciglitazone
分子名称: Ciglitazone, Peroxisome proliferator-activated receptor gamma
著者Shang, J, Kojetin, D.J.
登録日2019-03-05
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Quantitative structural assessment of graded receptor agonism.
Proc.Natl.Acad.Sci.USA, 116, 2019
6MD4
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BU of 6md4 by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Rosiglitazone and Oleic acid
分子名称: 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), OLEIC ACID, ...
著者Shang, J, Kojetin, D.J.
登録日2018-09-03
公開日2019-01-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.
Elife, 7, 2018
6MD1
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Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with GW9662 and Oleic acid
分子名称: 2-chloro-5-nitro-N-phenylbenzamide, OLEIC ACID, Peroxisome proliferator-activated receptor gamma
著者Shang, J, Kojetin, D.J.
登録日2018-09-03
公開日2019-01-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.
Elife, 7, 2018
6MCZ
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BU of 6mcz by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Arachidonic Acid
分子名称: ARACHIDONIC ACID, Peroxisome proliferator-activated receptor gamma
著者Shang, J, Kojetin, D.J.
登録日2018-09-03
公開日2019-01-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.
Elife, 7, 2018
8U8Q
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V290N/S292F Streptomyces coelicolor Laccase
分子名称: BORIC ACID, COPPER (II) ION, Copper oxidase, ...
著者Wang, J.-X, Lu, Y.
登録日2023-09-18
公開日2023-11-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations.
Angew.Chem.Int.Ed.Engl., 62, 2023
8U8P
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S292F Streptomyces coelicolor Laccase
分子名称: BORIC ACID, COPPER (II) ION, Copper oxidase, ...
著者Wang, J.-X, Lu, Y.
登録日2023-09-18
公開日2023-11-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations.
Angew.Chem.Int.Ed.Engl., 62, 2023
8U8R
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Y229F/V290N/S292F Streptomyces coelicolor Laccase
分子名称: BORIC ACID, COPPER (II) ION, Copper oxidase, ...
著者Wang, J.-X, Lu, Y.
登録日2023-09-18
公開日2023-11-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations.
Angew.Chem.Int.Ed.Engl., 62, 2023
8U8S
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Y229F/S292F Streptomyces coelicolor Laccase
分子名称: BORIC ACID, COPPER (II) ION, Copper oxidase, ...
著者Wang, J.-X, Lu, Y.
登録日2023-09-18
公開日2023-11-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations.
Angew.Chem.Int.Ed.Engl., 62, 2023
8U8T
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Y229F/V290N Streptomyces coelicolor Laccase
分子名称: BORIC ACID, COPPER (II) ION, Copper oxidase, ...
著者Wang, J.-X, Lu, Y.
登録日2023-09-18
公開日2023-11-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations.
Angew.Chem.Int.Ed.Engl., 62, 2023

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件を2024-07-10に公開中

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