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PDB: 4152 件

1R4L
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Inhibitor Bound Human Angiotensin Converting Enzyme-Related Carboxypeptidase (ACE2)
分子名称: (S,S)-2-{1-CARBOXY-2-[3-(3,5-DICHLORO-BENZYL)-3H-IMIDAZOL-4-YL]-ETHYLAMINO}-4-METHYL-PENTANOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Towler, P, Staker, B, Prasad, S.G, Menon, S, Ryan, D, Tang, J, Parsons, T, Fisher, M, Williams, D, Dales, N.A, Patane, M.A, Pantoliano, M.W.
登録日2003-10-07
公開日2004-02-03
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis.
J.Biol.Chem., 279, 2004
1RIH
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Crystal Structure of Fab 14F7, a unique anti-tumor antibody specific for N-glycolyl GM3
分子名称: heavy chain of antibody 14F7, light chain of antibody 14F7
著者Krengel, U, Olsson, L.-L, Martinez, C, Talavera, A, Rojas, G, Mier, E, Angstrom, J, Moreno, E.
登録日2003-11-17
公開日2004-01-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and Molecular Interactions of a Unique Antitumor Antibody Specific for N-Glycolyl GM3.
J.Biol.Chem., 279, 2004
1NR7
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Crystal structure of apo bovine glutamate dehydrogenase
分子名称: Glutamate dehydrogenase 1
著者Banerjee, S, Schmidt, T, Fang, J, Stanley, C.A, Smith, T.J.
登録日2003-01-23
公開日2003-05-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation
Biochemistry, 42, 2003
1M1C
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Structure of the L-A virus
分子名称: Major coat protein
著者Naitow, H, Tang, J, Canady, M, Wickner, R.B, Johnson, J.E.
登録日2002-06-18
公開日2002-10-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献L-A virus at 3.4 A resolution reveals particle architecture and mRNA decapping mechanism.
Nat.Struct.Biol., 9, 2002
1N4M
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Structure of Rb tumor suppressor bound to the transactivation domain of E2F-2
分子名称: Retinoblastoma Pocket, Transcription factor E2F2
著者Lee, C, Chang, J.H, Lee, H.S, Cho, Y.
登録日2002-10-31
公開日2003-01-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor
GENES DEV., 16, 2002
1S28
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Crystal Structure of AvrPphF ORF1, the Chaperone for the Type III Effector AvrPphF ORF2 from P. syringae
分子名称: ORF1, SULFATE ION
著者Singer, A.U, Desveaux, D, Betts, L, Chang, J.H, Nimchuk, Z, Grant, S.R, Dangl, J.L, Sondek, J.
登録日2004-01-08
公開日2004-09-14
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structures of the Type III Effector Protein AvrPphF and Its Chaperone Reveal Residues Required for Plant Pathogenesis
Structure, 12, 2004
1WT9
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crystal structure of Aa-X-bp-I, a snake venom protein with the activity of binding to coagulation factor X from Agkistrodon acutus
分子名称: CALCIUM ION, agkisacutacin A chain, anticoagulant protein-B
著者Zhu, Z, Liu, S, Mo, X, Yu, X, Liang, Z, Zang, J, Zhao, W, Teng, M, Niu, L.
登録日2004-11-18
公開日2006-03-07
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Characterizations and Crystal structures of two snake venom proteins with the activity of binding coagulation factor X from Agkistrodon acutus
To be Published
1O5D
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Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)
分子名称: 2-{5-[AMINO(IMINIO)METHYL]-6-FLUORO-1H-BENZIMIDAZOL-2-YL}-6-[(2-METHYLCYCLOHEXYL)OXY]BENZENOLATE, Coagulation factor VII, Tissue factor
著者Katz, B.A, Luong, C, Ho, J.D, Somoza, J.R, Gjerstad, E, Tang, J, Williams, S.R, Verner, E, Mackman, R.L, Young, W.B, Sprengeler, P.A, Chan, H, Mortara, K, Janc, J.W, McGrath, M.E.
登録日2003-09-09
公開日2004-09-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA).
J.Mol.Biol., 344, 2004
1OLS
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Roles of His291-alpha and His146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase
分子名称: 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, GLYCEROL, ...
著者Wynn, R.M, Machius, M, Chuang, J.L, Li, J, Tomchick, D.R, Chuang, D.T.
登録日2003-08-12
公開日2003-08-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Roles of His291-Alpha and His146-Beta' in the Reductive Acylation Reaction Catalyzed by Human Branched-Chain Alpha-Ketoacid Dehydrogenase: Refined Phosphorylation Loop Structure in the Active Site.
J.Biol.Chem., 278, 2003
1ITZ
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Maize Transketolase in complex with TPP
分子名称: MAGNESIUM ION, THIAMINE DIPHOSPHATE, Transketolase
著者Gerhardt, S, Echt, S, Bader, G, Freigang, J, Busch, M, Bacher, A, Huber, R, Fischer, M.
登録日2002-02-15
公開日2003-02-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and properties of an engineered transketolase from maize
PLANT PHYSIOL., 132, 2003
1SZU
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The structure of gamma-aminobutyrate aminotransferase mutant: V241A
分子名称: 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-aminobutyrate aminotransferase, ...
著者Liu, W, Peterson, P.E, Langston, J.A, Jin, X, Zhou, X, Fisher, A.J, Toney, M.D.
登録日2004-04-06
公開日2005-03-01
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Kinetic and Crystallographic Analysis of Active Site Mutants of Escherichia coligamma-Aminobutyrate Aminotransferase.
Biochemistry, 44, 2005
1O5A
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Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)
分子名称: 3-{5-[AMINO(IMINIO)METHYL]-1H-INDOL-2-YL}-1,1'-BIPHENYL-2-OLATE, CITRIC ACID, Urokinase-type plasminogen activator
著者Katz, B.A, Luong, C, Ho, J.D, Somoza, J.R, Gjerstad, E, Tang, J, Williams, S.R, Verner, E, Mackman, R.L, Young, W.B, Sprengeler, P.A, Chan, H, Mortara, K, Janc, J.W, McGrath, M.E.
登録日2003-09-09
公開日2004-09-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA)
J.Mol.Biol., 344, 2004
1N6A
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Structure of SET7/9
分子名称: S-ADENOSYLMETHIONINE, SET domain-containing protein 7
著者Kwon, T.W, Chang, J.H, Kwak, E, Lee, C.W, Joachimiak, A, Kim, Y.C, Lee, J, Cho, Y.
登録日2002-11-09
公開日2003-02-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet
EMBO J., 22, 2003
1N6C
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Structure of SET7/9
分子名称: S-ADENOSYLMETHIONINE, SET domain-containing protein 7
著者Kwon, T.W, Chang, J.H, Cho, Y.
登録日2002-11-09
公開日2003-02-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet
EMBO J., 22, 2003
1N6V
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Average structure of the interferon-binding ectodomain of the human type I interferon receptor
分子名称: Interferon-alpha/beta receptor beta chain
著者Chill, J.H, Quadt, S.R, Levy, R, Schreiber, G, Anglister, J.
登録日2002-11-12
公開日2003-07-15
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献The human type I interferon receptor. NMR structure reveals the molecular basis of ligand binding.
Structure, 11, 2003
1MKY
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Structural Analysis of the Domain Interactions in Der, a Switch Protein Containing Two GTPase Domains
分子名称: GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, Probable GTP-binding protein engA
著者Robinson, V.L, Hwang, J, Fox, E, Inouye, M, Stock, A.M.
登録日2002-08-29
公開日2003-01-14
最終更新日2015-02-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Domain Arrangement of Der, a Switch Protein Containing Two GTPase Domains
Structure, 10, 2002
1R42
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Native Human Angiotensin Converting Enzyme-Related Carboxypeptidase (ACE2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ZINC ION, ...
著者Towler, P, Staker, B, Prasad, S.G, Menon, S, Ryan, D, Tang, J, Parsons, T, Fisher, M, Williams, D, Dales, N.A, Patane, M.A, Pantoliano, M.W.
登録日2003-10-07
公開日2004-02-03
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis.
J.Biol.Chem., 279, 2004
1BXP
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SOLUTION NMR STRUCTURE OF THE COMPLEX OF ALPHA-BUNGAROTOXIN WITH A LIBRARY DERIVED PEPTIDE, 20 STRUCTURES
分子名称: ALPHA-BUNGAROTOXIN, PEPTIDE MET-ARG-TYR-TYR-GLU-SER-SER-LEU-LYS-SER-TYR-PRO-ASP
著者Scherf, T, Balass, M, Fuchs, S, Katchalski-Katzir, E, Anglister, J.
登録日1998-08-23
公開日1999-01-27
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Three-dimensional solution structure of the complex of alpha-bungarotoxin with a library-derived peptide.
Proc.Natl.Acad.Sci.USA, 94, 1997
1U6U
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NMR structure of a V3 (IIIB isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody
分子名称: V3 peptide
著者Rosen, O, Chill, J, Sharon, M, Kessler, N, Mester, B, Zolla-Pazner, S, Anglister, J.
登録日2004-08-02
公開日2005-04-05
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Induced fit in HIV-neutralizing antibody complexes: evidence for alternative conformations of the gp120 V3 loop and the molecular basis for broad neutralization.
Biochemistry, 44, 2005
1O5C
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Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)
分子名称: 2-{5-[AMINO(IMINIO)METHYL]-6-FLUORO-1H-BENZIMIDAZOL-2-YL}-6-[(2-METHYLCYCLOHEXYL)OXY]BENZENOLATE, CITRIC ACID, Urokinase-type plasminogen activator
著者Katz, B.A, Luong, C, Ho, J.D, Somoza, J.R, Gjerstad, E, Tang, J, Williams, S.R, Verner, E, Mackman, R.L, Young, W.B, Sprengeler, P.A, Chan, H, Mortara, K, Janc, J.W, McGrath, M.E.
登録日2003-09-09
公開日2004-09-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA)
J.Mol.Biol., 344, 2004
1NQT
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Crystal structure of bovine Glutamate dehydrogenase-ADP complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Glutamate dehydrogenase 1
著者Banerjee, S, Schmidt, T, Fang, J, Stanley, C.A, Smith, T.J.
登録日2003-01-23
公開日2003-05-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation
Biochemistry, 42, 2003
1O5B
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Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)
分子名称: 4-IODOBENZO[B]THIOPHENE-2-CARBOXAMIDINE, CITRIC ACID, Urokinase-type plasminogen activator
著者Katz, B.A, Luong, C, Ho, J.D, Somoza, J.R, Gjerstad, E, Tang, J, Williams, S.R, Verner, E, Mackman, R.L, Young, W.B, Sprengeler, P.A, Chan, H, Mortara, K, Janc, J.W, McGrath, M.E.
登録日2003-09-09
公開日2004-09-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA)
J.Mol.Biol., 344, 2004
1O5G
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Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)
分子名称: 2-{5-[AMINO(IMINIO)METHYL]-6-FLUORO-1H-BENZIMIDAZOL-2-YL}-6-[(2-METHYLCYCLOHEXYL)OXY]BENZENOLATE, CALCIUM ION, Hirudin IIIB', ...
著者Katz, B.A, Luong, C, Ho, J.D, Somoza, J.R, Gjerstad, E, Tang, J, Williams, S.R, Verner, E, Mackman, R.L, Young, W.B, Sprengeler, P.A, Chan, H, Mortara, K, Janc, J.W, McGrath, M.E.
登録日2003-09-09
公開日2004-09-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA).
J.Mol.Biol., 344, 2004
1S21
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Crystal Structure of AvrPphF ORF2, A Type III Effector from P. syringae
分子名称: ORF2
著者Singer, A.U, Desveaux, D, Betts, L, Chang, J.H, Nimchuk, Z, Grant, S.R, Dangl, J.K, Sondek, J.
登録日2004-01-07
公開日2004-09-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of the Type III Effector Protein AvrPphF and Its Chaperone Reveal Residues Required for Plant Pathogenesis
Structure, 12, 2004
1SF2
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Structure of E. coli gamma-aminobutyrate aminotransferase
分子名称: 1,2-ETHANEDIOL, 4-aminobutyrate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ...
著者Liu, W, Peterson, P.E, Carter, R.J, Zhou, X, Langston, J.A, Fisher, A.J, Toney, M.D.
登録日2004-02-19
公開日2004-09-14
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of unbound and aminooxyacetate-bound Escherichia coli gamma-aminobutyrate aminotransferase.
Biochemistry, 43, 2004

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