8PYI
| Human IGF1R with inhibitor 6 | 分子名称: | 3-[8-azanyl-1-(4-ethoxy-8-fluoranyl-2-phenyl-quinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methyl-cyclobutan-1-ol, Insulin-like growth factor 1 receptor beta chain | 著者 | Dreyer, M.K, Wang, J, Elkins, J.M. | 登録日 | 2023-07-25 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | 主引用文献 | Human IGF1R with inhibitor 6 To Be Published
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8PYJ
| Human IGF1R with inhibitor 8 | 分子名称: | 5,5-dimethyl-1-(quinolin-4-ylmethyl)-3-[4-(trifluoromethylsulfonyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ... | 著者 | Dreyer, M.K, Wang, J, Elkins, J.M. | 登録日 | 2023-07-25 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.702 Å) | 主引用文献 | Human IGF1R with inhibitor 8 To Be Published
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8PYK
| Human IGF1R with inhibitor 47 | 分子名称: | 5,5-dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione, Insulin-like growth factor 1 receptor beta chain, NICKEL (II) ION | 著者 | Dreyer, M.K, Wang, J, Elkins, J.M. | 登録日 | 2023-07-25 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Human IGF1R with inhibitor 47 To Be Published
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8PYL
| Human IGF1R with inhibitor 53 | 分子名称: | (5S)-5-methyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ... | 著者 | Dreyer, M.K, Wang, J, Elkins, J.M. | 登録日 | 2023-07-25 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | 主引用文献 | Human IGF1R with inhibitor 53 To Be Published
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8PYN
| Human IGF1R with inhibitor 56 | 分子名称: | 5,5-dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfonyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ... | 著者 | Dreyer, M.K, Wang, J, Elkins, J.M. | 登録日 | 2023-07-25 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Human IGF1R with inhibitor 56 To Be Published
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8PYM
| Human IGF1R with inhibitor 54 | 分子名称: | 5,5-dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ... | 著者 | Dreyer, M.K, Wang, J, Elkins, J.M. | 登録日 | 2023-07-25 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.652 Å) | 主引用文献 | Human IGF1R with inhibitor 54 To Be Published
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8IFF
| Cryo-EM structure of Arabidopsis phytochrome A. | 分子名称: | 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Phytochrome A | 著者 | Ma, L, Zhou, C, Wang, J, Guan, Z, Yin, P. | 登録日 | 2023-02-17 | 公開日 | 2023-08-02 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Plant phytochrome A in the Pr state assembles as an asymmetric dimer. Cell Res., 33, 2023
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5Z5K
| Structure of the DCC-Draxin complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Draxin, ... | 著者 | Liu, Y, Xiao, J, Wang, J. | 登録日 | 2018-01-18 | 公開日 | 2018-06-20 | 最終更新日 | 2021-03-10 | 実験手法 | X-RAY DIFFRACTION (2.493 Å) | 主引用文献 | Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC. Neuron, 97, 2018
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3CMZ
| TEM-1 Class-A beta-lactamase L201P mutant apo structure | 分子名称: | Beta-lactamase TEM, PHOSPHATE ION | 著者 | Marciano, D.C, Wang, X, Wang, J, Chen, Y, Thomas, V.L, Shoichet, B.K, Palzkill, T. | 登録日 | 2008-03-24 | 公開日 | 2008-11-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Genetic and structural characterization of an L201P global suppressor substitution in TEM-1 beta-lactamase J.Mol.Biol., 384, 2008
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6JPK
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3IZI
| Mm-cpn rls with ATP | 分子名称: | Chaperonin | 著者 | Douglas, N.R, Reissmann, S, Zhang, J, Chen, B, Jakana, J, Kumar, R, Chiu, W, Frydman, J. | 登録日 | 2010-10-29 | 公開日 | 2011-02-02 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | 主引用文献 | Dual Action of ATP Hydrolysis Couples Lid Closure to Substrate Release into the Group II Chaperonin Chamber. Cell(Cambridge,Mass.), 144, 2011
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3IZH
| Mm-cpn D386A with ATP | 分子名称: | Chaperonin | 著者 | Douglas, N.R, Reissmann, S, Zhang, J, Chen, B, Jakana, J, Kumar, R, Chiu, W, Frydman, J. | 登録日 | 2010-10-29 | 公開日 | 2011-02-02 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (11 Å) | 主引用文献 | Dual Action of ATP Hydrolysis Couples Lid Closure to Substrate Release into the Group II Chaperonin Chamber. Cell(Cambridge,Mass.), 144, 2011
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6JJT
| Crystal structure of an enzyme from Penicillium herquei in condition1 | 分子名称: | CITRIC ACID, DI(HYDROXYETHYL)ETHER, PhnH | 著者 | Fen, Y, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2019-02-26 | 公開日 | 2020-01-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | 主引用文献 | Crystal structure and proposed mechanism of an enantioselective hydroalkoxylation enzyme from Penicillium herquei. Biochem.Biophys.Res.Commun., 516, 2019
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3IZM
| Mm-cpn wildtype with ATP | 分子名称: | Chaperonin | 著者 | Douglas, N.R, Reissmann, S, Zhang, J, Chen, B, Jakana, J, Kumar, R, Chiu, W, Frydman, J. | 登録日 | 2010-10-30 | 公開日 | 2011-02-02 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | 主引用文献 | Dual Action of ATP Hydrolysis Couples Lid Closure to Substrate Release into the Group II Chaperonin Chamber. Cell(Cambridge,Mass.), 144, 2011
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3IZN
| Mm-cpn deltalid with ATP | 分子名称: | Chaperonin | 著者 | Douglas, N.R, Reissmann, S, Zhang, J, Chen, B, Jakana, J, Kumar, R, Chiu, W, Frydman, J. | 登録日 | 2010-10-30 | 公開日 | 2011-02-02 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (6.4 Å) | 主引用文献 | Dual Action of ATP Hydrolysis Couples Lid Closure to Substrate Release into the Group II Chaperonin Chamber. Cell(Cambridge,Mass.), 144, 2011
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3IZL
| Mm-cpn rls deltalid with ATP and AlFx | 分子名称: | Mm-cpn rls deltalid | 著者 | Douglas, N.R, Reissmann, S, Zhang, J, Chen, B, Jakana, J, Kumar, R, Chiu, W, Frydman, J. | 登録日 | 2010-10-29 | 公開日 | 2011-02-02 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | 主引用文献 | Dual Action of ATP Hydrolysis Couples Lid Closure to Substrate Release into the Group II Chaperonin Chamber. Cell(Cambridge,Mass.), 144, 2011
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3IZK
| Mm-cpn rls deltalid with ATP | 分子名称: | Chaperonin | 著者 | Douglas, N.R, Reissmann, S, Zhang, J, Chen, B, Jakana, J, Kumar, R, Chiu, W, Frydman, J. | 登録日 | 2010-10-29 | 公開日 | 2011-02-02 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Dual Action of ATP Hydrolysis Couples Lid Closure to Substrate Release into the Group II Chaperonin Chamber. Cell(Cambridge,Mass.), 144, 2011
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3J1T
| High affinity dynein microtubule binding domain - tubulin complex | 分子名称: | Cytoplasmic dynein 1 heavy chain 1, seryl t-RNA synthetase chimera, Tubulin alpha-1B chain, ... | 著者 | Redwine, W.B, Hernandez-Lopez, R, Zou, S, Huang, J, Reck-Peterson, S.L, Leschziner, A.E. | 登録日 | 2012-06-25 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (9.7 Å) | 主引用文献 | Structural basis for microtubule binding and release by dynein. Science, 337, 2012
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4CDX
| Crystal structure of human Enterovirus 71 in complex with the uncoating inhibitor GPP12 | 分子名称: | 1-(5-((3'-METHYL-[1,1'-BIPHENYL]-4-YL)OXY)PENTYL)-3-(, SODIUM ION, VP1, ... | 著者 | De Colibus, L, Wang, X, Spyrou, J.A.B, Kelly, J, Ren, J, Grimes, J, Puerstinger, G, Stonehouse, N, Walter, T.S, Hu, Z, Wang, J, Li, X, Peng, W, Rowlands, D, Fry, E.E, Rao, Z, Stuart, D.I. | 登録日 | 2013-11-07 | 公開日 | 2014-02-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules. Nat.Struct.Mol.Biol., 21, 2014
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4GSB
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4ZJS
| Crystal structure of a chimeric acetylcholine binding protein from Aplysia Californica (Ac-AChBP) containing the main immunogenic region (MIR) from the human alpha 1 subunit of the muscle nicotinic acetylcholine receptor in complex with anatoxin-A. | 分子名称: | 1-[(1R,6R)-9-azabicyclo[4.2.1]non-2-en-2-yl]ethanone, Acetylcholine receptor subunit alpha,Soluble acetylcholine receptor,Acetylcholine receptor subunit alpha,Soluble acetylcholine receptor | 著者 | Talley, T.T, Bobango, J, Wu, J, Park, J.F, Luo, J, Lindsatrom, J, Taylor, P. | 登録日 | 2015-04-29 | 公開日 | 2015-05-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.2301 Å) | 主引用文献 | Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and agonist sensitivity. J. Neurosci., 29, 2009
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4RNY
| Structure of Helicobacter pylori Csd3 from the orthorhombic crystal | 分子名称: | Conserved hypothetical secreted protein, GLYCEROL, SULFATE ION, ... | 著者 | An, D.R, Kim, H.S, Kim, J, Im, H.N, Yoon, H.J, Yoon, J.Y, Jang, J.Y, Hesek, D, Lee, M, Mobashery, S, Kim, S.-J, Lee, B.I, Suh, S.W. | 登録日 | 2014-10-27 | 公開日 | 2015-03-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of Csd3 from Helicobacter pylori, a cell shape-determining metallopeptidase. Acta Crystallogr.,Sect.D, 71, 2015
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5L4M
| Crystal Structure of Human Transthyretin in Complex with 3,5,6-Trichloro-2-pyridinyloxyacetic acid (Triclopyr) | 分子名称: | SODIUM ION, Transthyretin, Triclopyr | 著者 | Grundstrom, C, Hall, M, Zhang, J, Olofsson, A, Andersson, P, Sauer-Eriksson, A.E. | 登録日 | 2016-05-25 | 公開日 | 2016-10-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.581 Å) | 主引用文献 | Structure-Based Virtual Screening Protocol for in Silico Identification of Potential Thyroid Disrupting Chemicals Targeting Transthyretin. Environ. Sci. Technol., 50, 2016
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4CEY
| Crystal structure of human Enterovirus 71 in complex with the uncoating inhibitor NLD | 分子名称: | 1-(2-aminopyridin-4-yl)-3-[(3S)-5-{4-[(E)-(ethoxyimino)methyl]phenoxy}-3-methylpentyl]imidazolidin-2-one, SODIUM ION, VP1, ... | 著者 | De Colibus, L, Wang, X, Spyrou, J.A.B, Kelly, J, Ren, J, Grimes, J, Puerstinger, G, Stonehouse, N, Walter, T.S, Hu, Z, Wang, J, Li, X, Peng, W, Rowlands, D, Fry, E.E, Rao, Z, Stuart, D.I. | 登録日 | 2013-11-12 | 公開日 | 2014-02-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules Nat.Struct.Mol.Biol., 21, 2014
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5ZM7
| Crystal structure of ORP1-ORD in complex with cholesterol at 3.4 A resolution | 分子名称: | CHOLESTEROL, Oxysterol-binding protein-related protein 1 | 著者 | Dong, J, Wang, J, Wu, J.W. | 登録日 | 2018-04-01 | 公開日 | 2019-02-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.401 Å) | 主引用文献 | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2. Nat Commun, 10, 2019
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