1SZK
| The structure of gamma-aminobutyrate aminotransferase mutant: E211S | Descriptor: | 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-aminobutyrate aminotransferase, ... | Authors: | Liu, W, Peterson, P.E, Langston, J.A, Jin, X, Fisher, A.J, Toney, M.D. | Deposit date: | 2004-04-05 | Release date: | 2005-03-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Kinetic and Crystallographic Analysis of Active Site Mutants of Escherichia coligamma-Aminobutyrate Aminotransferase. Biochemistry, 44, 2005
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1XN3
| Crystal structure of Beta-secretase bound to a long inhibitor with additional upstream residues. | Descriptor: | Beta-secretase 1, Peptidic inhibitor | Authors: | Turner III, R.T, Hong, L, Koelsch, G, Ghosh, A.K, Tang, J. | Deposit date: | 2004-10-04 | Release date: | 2005-03-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural locations and functional roles of new subsites S5, S6, and S7 in memapsin 2 (beta-secretase). Biochemistry, 44, 2005
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1F42
| THE P40 DOMAIN OF HUMAN INTERLEUKIN-12 | Descriptor: | 5-MERCAPTO-2-NITRO-BENZOIC ACID, INTERLEUKIN-12 BETA CHAIN, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Yoon, C, Johnston, S.C, Tang, J, Tobin, J.F, Somers, W.S. | Deposit date: | 2000-06-07 | Release date: | 2001-06-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12. EMBO J., 19, 2000
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1JRV
| SOLUTION STRUCTURE OF DAATAA DNA BULGE | Descriptor: | 5'-D(*CP*GP*TP*AP*GP*CP*CP*GP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*TP*CP*GP*AP*AP*TP*AP*AP*GP*CP*TP*AP*CP*G)-3' | Authors: | Gollmick, F.A, Lorenz, M, Dornberger, U, von Langen, J, Diekmann, S, Fritzsche, H. | Deposit date: | 2001-08-15 | Release date: | 2002-06-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of dAATAA and dAAUAA DNA bulges. Nucleic Acids Res., 30, 2002
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2B4D
| SSAT+COA+SP- SP disordered | Descriptor: | COENZYME A, Diamine acetyltransferase 1 | Authors: | Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2005-09-23 | Release date: | 2006-01-17 | Last modified: | 2021-02-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target Proc.Natl.Acad.Sci.Usa, 103, 2006
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1B03
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2B3U
| Human Spermine spermidine acetyltransferase K26R mutant | Descriptor: | Diamine acetyltransferase 1, SULFATE ION | Authors: | Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2005-09-21 | Release date: | 2006-01-17 | Last modified: | 2021-02-03 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target. Proc.Natl.Acad.Sci.USA, 103, 2006
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1JS7
| Solution Structure of dAAUAA DNA Bulge | Descriptor: | 5'-D(*CP*GP*TP*AP*GP*CP*CP*GP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*TP*CP*GP*AP*AP*UP*AP*AP*GP*CP*TP*AP*CP*G)-3' | Authors: | Gollmick, F.A, Lorenz, M, Dornberger, U, von Langen, J, Diekmann, S, Fritzsche, H. | Deposit date: | 2001-08-16 | Release date: | 2002-06-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of dAATAA and dAAUAA DNA bulges. Nucleic Acids Res., 30, 2002
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1PCW
| Aquifex aeolicus KDO8PS in complex with cadmium and APP, a bisubstrate inhibitor | Descriptor: | 1-DEOXY-6-O-PHOSPHONO-1-[(PHOSPHONOMETHYL)AMINO]-L-THREO-HEXITOL, 2-dehydro-3-deoxyphosphooctonate aldolase, CADMIUM ION | Authors: | Xu, X, Wang, J, Grison, C, Petek, S, Coutrot, P, Birck, M, Woodard, R.W, Gatti, D.L. | Deposit date: | 2003-05-17 | Release date: | 2004-02-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure-Based Design of Novel Inhibitors of 3-Deoxy-D-manno-octulosonate 8-Phosphate Synthase. Drug DES.DISCOVERY, 18, 2003
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1XS7
| Crystal Structure of a cycloamide-urethane-derived novel inhibitor bound to human brain memapsin 2 (beta-secretase). | Descriptor: | Beta-secretase 1, N-[(4S,5S,7R)-8-({(S)-1-[(BENZYLAMINO)OXOMETHYL]-2-METHYLPROPYL}AMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXO-OCT-4-YL]-(4S,7S)-4 -ISOPROPYL-2,5,9-TRIOXO-1-OXA-3,6,10-TRIAZACYCLOHEXADECANE-7-CARBOXAMIDE | Authors: | Ghosh, A, Devasamudram, T, Hong, L, DeZutter, C, Xu, X, Weerasena, V, Koelsch, G, Bilcer, G, Tang, J. | Deposit date: | 2004-10-18 | Release date: | 2004-12-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-based design of cycloamide-urethane-derived novel inhibitors of human brain memapsin 2 (beta-secretase). Bioorg.Med.Chem.Lett., 15, 2005
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1SZS
| The structure of gamma-aminobutyrate aminotransferase mutant: I50Q | Descriptor: | 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-aminobutyrate aminotransferase, ... | Authors: | Liu, W, Peterson, P.E, Langston, J.A, Jin, X, Zhou, X, Fisher, A.J, Toney, M.D. | Deposit date: | 2004-04-06 | Release date: | 2005-03-01 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Kinetic and Crystallographic Analysis of Active Site Mutants of Escherichia coligamma-Aminobutyrate Aminotransferase. Biochemistry, 44, 2005
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1JRW
| Solution Structure of dAATAA DNA Bulge | Descriptor: | 5'-D(*CP*GP*TP*AP*GP*CP*CP*GP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*TP*CP*GP*AP*AP*TP*AP*AP*GP*CP*TP*AP*CP*G)-3' | Authors: | Gollmick, F.A, Lorenz, M, Dornberger, U, von Langen, J, Diekmann, S, Fritzsche, H. | Deposit date: | 2001-08-15 | Release date: | 2002-08-28 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of dAATAA and dAAUAA DNA bulges. Nucleic Acids Res., 30, 2002
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1Y17
| crystal structure of Aa-X-bp-II, a snake venom protein with the activity of binding to coagulation factor X from Agkistrodon acutus | Descriptor: | CALCIUM ION, anticoagulant protein A, anticoagulant protein-B | Authors: | Zhu, Z, Liu, S, Mo, X, Yu, X, Liang, Z, Zang, J, Zhao, W, Teng, M, Niu, L. | Deposit date: | 2004-11-17 | Release date: | 2006-03-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Characterizations and Crystal structures of two snake venom proteins with the activity of binding coagulation factor X from Agkistrodon acutus To be Published
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1LCX
| NMR structure of HIV-1 gp41 659-671 13mer peptide | Descriptor: | GP41 | Authors: | Biron, Z, Khare, S, Samson, A.O, Hayek, Y, Naider, F, Anglister, J. | Deposit date: | 2002-04-07 | Release date: | 2002-12-04 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A Monomeric 3(10)-Helix Is Formed in Water by a 13-Residue Peptide
Representing the Neutralizing Determinant of HIV-1 on gp41. Biochemistry, 41, 2002
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1LQH
| INSECTICIDAL ALPHA SCORPION TOXIN ISOLATED FROM THE VENOM OF SCORPION LEIURUS QUINQUESTRIATUS HEBRAEUS, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | INSECT TOXIN ALPHA | Authors: | Tugarinov, V, Kustanovich, I, Zilberberg, N, Gurevitz, M, Anglister, J. | Deposit date: | 1996-06-17 | Release date: | 1997-03-12 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structures of a highly insecticidal recombinant scorpion alpha-toxin and a mutant with increased activity. Biochemistry, 36, 1997
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1LQI
| INSECTICIDAL ALPHA SCORPION TOXIN ISOLATED FROM THE VENOM OF SCORPION LEIURUS QUINQUESTRIATUS HEBRAEUS, NMR, 29 STRUCTURES | Descriptor: | INSECT TOXIN ALPHA | Authors: | Tugarinov, V, Kustanovich, I, Zilberberg, N, Gurevitz, M, Anglister, J. | Deposit date: | 1996-06-17 | Release date: | 1997-03-12 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structures of a highly insecticidal recombinant scorpion alpha-toxin and a mutant with increased activity. Biochemistry, 36, 1997
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1QNZ
| NMR structure of the 0.5b anti-HIV antibody complex with the gp120 V3 peptide | Descriptor: | 0.5B ANTIBODY (HEAVY CHAIN), 0.5B ANTIBODY (LIGHT CHAIN), GP120 | Authors: | Tugarinov, V, Zvi, A, Levy, R, Hayek, Y, Matsushita, S, Anglister, J. | Deposit date: | 1999-10-26 | Release date: | 2000-06-03 | Last modified: | 2018-01-17 | Method: | SOLUTION NMR | Cite: | NMR Structure of an Anti-Gp120 Antibody Complex with a V3 Peptide Reveals a Surface Important for Co-Receptor Binding Structure, 8, 2000
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1NIZ
| NMR structure of a V3 (MN isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody | Descriptor: | Exterior membrane glycoprotein(GP120) | Authors: | Sharon, M, Kessler, N, Levy, R, Zolla-Pazner, S, Gorlach, M, Anglister, J. | Deposit date: | 2002-12-30 | Release date: | 2003-02-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Alternative Conformations of HIV-1 V3 Loops Mimic
beta Hairpins in Chemokines, Suggesting a Mechanism
for Coreceptor Selectivity. Structure, 11, 2003
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1NJ0
| NMR structure of a V3 (MN isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody | Descriptor: | Exterior membrane glycoprotein(GP120) | Authors: | Sharon, M, Kessler, N, Levy, R, Zolla-Pazner, S, Gorlach, M, Anglister, J. | Deposit date: | 2002-12-30 | Release date: | 2003-02-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Alternative Conformations of HIV-1 V3 Loops Mimic
beta Hairpins in Chemokines, Suggesting a Mechanism
for Coreceptor Selectivity. Structure, 11, 2003
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1M4H
| Crystal Structure of Beta-secretase complexed with Inhibitor OM00-3 | Descriptor: | Inhibitor OM00-3, beta-Secretase | Authors: | Hong, L, Turner, R.T, Koelsch, G, Ghosh, A.K, Tang, J. | Deposit date: | 2002-07-02 | Release date: | 2002-08-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of Memapsin 2 (beta-Secretase) in Complex with Inhibitor OM00-3 Biochemistry, 41, 2002
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1SP8
| 4-Hydroxyphenylpyruvate Dioxygenase | Descriptor: | 4-Hydroxyphenylpyruvate Dioxygenase, FE (II) ION | Authors: | Fritze, I.M, Linden, L, Freigang, J, Auerbach, G, Huber, R, Steinbacher, S. | Deposit date: | 2004-03-16 | Release date: | 2004-09-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structures of Zea mays and Arabidopsis 4-Hydroxyphenylpyruvate Dioxygenase Plant physiol., 134, 2004
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1SGZ
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1SP9
| 4-Hydroxyphenylpyruvate Dioxygenase | Descriptor: | 4-hydroxyphenylpyruvate dioxygenase, FE (II) ION | Authors: | Fritze, I.M, Linden, L, Freigang, J, Auerbach, G, Huber, R, Steinbacher, S. | Deposit date: | 2004-03-16 | Release date: | 2004-09-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The crystal structures of Zea mays and Arabidopsis 4-Hydroxyphenylpyruvate Dioxygenase Plant Physiol., 134, 2004
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