2B58
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![BU of 2b58 by Molmil](/molmil-images/mine/2b58) | SSAT with coa_sp, spermine disordered, K26R mutant | Descriptor: | COENZYME A, Diamine acetyltransferase 1 | Authors: | Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2005-09-27 | Release date: | 2006-01-24 | Last modified: | 2021-02-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target Proc.Natl.Acad.Sci.Usa, 103, 2006
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1KEO
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![BU of 1keo by Molmil](/molmil-images/mine/1keo) | TWISTS AND TURNS OF THE CD-MPR: LIGAND-BOUND VERSUS LIGAND-FREE RECEPTOR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, cation-dependent mannose-6-phosphate receptor | Authors: | Olson, L.J, Zhang, J, Dahms, N.M, Kim, J.J. | Deposit date: | 2001-11-16 | Release date: | 2002-01-23 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Twists and turns of the cation-dependent mannose 6-phosphate receptor. Ligand-bound versus ligand-free receptor J.Biol.Chem., 277, 2002
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2B4D
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![BU of 2b4d by Molmil](/molmil-images/mine/2b4d) | SSAT+COA+SP- SP disordered | Descriptor: | COENZYME A, Diamine acetyltransferase 1 | Authors: | Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2005-09-23 | Release date: | 2006-01-17 | Last modified: | 2021-02-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target Proc.Natl.Acad.Sci.Usa, 103, 2006
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2B3V
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![BU of 2b3v by Molmil](/molmil-images/mine/2b3v) | Spermine spermidine acetyltransferase in complex with acetylcoa, K26R mutant | Descriptor: | ACETYL COENZYME *A, Diamine acetyltransferase 1 | Authors: | Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2005-09-21 | Release date: | 2006-01-17 | Last modified: | 2021-02-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target. Proc.Natl.Acad.Sci.USA, 103, 2006
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2B4B
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![BU of 2b4b by Molmil](/molmil-images/mine/2b4b) | SSAT+COA+BE-3-3-3, K26R mutant | Descriptor: | COENZYME A, Diamine acetyltransferase 1, N-ETHYL-N-[3-(PROPYLAMINO)PROPYL]PROPANE-1,3-DIAMINE | Authors: | Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2005-09-23 | Release date: | 2006-01-17 | Last modified: | 2023-05-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target Proc.Natl.Acad.Sci.Usa, 103, 2006
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2B3U
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![BU of 2b3u by Molmil](/molmil-images/mine/2b3u) | Human Spermine spermidine acetyltransferase K26R mutant | Descriptor: | Diamine acetyltransferase 1, SULFATE ION | Authors: | Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2005-09-21 | Release date: | 2006-01-17 | Last modified: | 2021-02-03 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target. Proc.Natl.Acad.Sci.USA, 103, 2006
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2EBO
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![BU of 2ebo by Molmil](/molmil-images/mine/2ebo) | CORE STRUCTURE OF GP2 FROM EBOLA VIRUS | Descriptor: | CHLORIDE ION, EBOLA VIRUS ENVELOPE GLYCOPROTEIN | Authors: | Malashkevich, V.N, Schneider, B.J, Mcnally, M.L, Milhollen, M.A, Pang, J.X, Kim, P.S. | Deposit date: | 1998-12-24 | Release date: | 1999-05-18 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Core structure of the envelope glycoprotein GP2 from Ebola virus at 1.9-A resolution. Proc.Natl.Acad.Sci.USA, 96, 1999
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2FXY
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![BU of 2fxy by Molmil](/molmil-images/mine/2fxy) | |
2Q8F
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![BU of 2q8f by Molmil](/molmil-images/mine/2q8f) | Structure of pyruvate dehydrogenase kinase isoform 1 | Descriptor: | POTASSIUM ION, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1 | Authors: | Kato, M, Li, J, Chuang, J.L, Chuang, D.T. | Deposit date: | 2007-06-10 | Release date: | 2007-07-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol. Structure, 15, 2007
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1M60
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![BU of 1m60 by Molmil](/molmil-images/mine/1m60) | Solution Structure of Zinc-substituted cytochrome c | Descriptor: | ZINC SUBSTITUTED HEME C, Zinc-substituted cytochrome c | Authors: | Qian, C, Yao, Y, Tong, Y, Wang, J, Tang, W. | Deposit date: | 2002-07-11 | Release date: | 2002-08-07 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Structural analysis of zinc-substituted cytochrome c. J.Biol.Inorg.Chem., 8, 2003
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4QAB
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![BU of 4qab by Molmil](/molmil-images/mine/4qab) | X-RAY STRUCTURE of ACETYLCHOLINE BINDING PROTEIN (ACHBP) IN COMPLEX WITH 4-(MORPHOLIN-4-YL)-6-[4-(TRIFLUOROMETHYL)PHENYL]PYRIMIDIN-2-AMINE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(morpholin-4-yl)-6-[4-(trifluoromethyl)phenyl]pyrimidin-2-amine, Acetylcholine-binding protein, ... | Authors: | Kaczanowska, K, Harel, M, Radic, Z, Changeux, J.-P, Finn, M.G, Taylor, P. | Deposit date: | 2014-05-03 | Release date: | 2014-07-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.984 Å) | Cite: | Structural basis for cooperative interactions of substituted 2-aminopyrimidines with the acetylcholine binding protein. Proc.Natl.Acad.Sci.USA, 111, 2014
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2JYH
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![BU of 2jyh by Molmil](/molmil-images/mine/2jyh) | |
1T6W
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![BU of 1t6w by Molmil](/molmil-images/mine/1t6w) | RATIONAL DESIGN OF A CALCIUM-BINDING ADHESION PROTEIN NMR, 20 STRUCTURES | Descriptor: | CALCIUM ION, hypothetical protein XP_346638 | Authors: | Yang, W, Wilkins, A.L, Ye, Y, Liu, Z.-R, Urbauer, J.L, Kearney, A, van der Merwe, P.A, Yang, J.J. | Deposit date: | 2004-05-07 | Release date: | 2005-02-15 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Design of a calcium-binding protein with desired structure in a cell adhesion molecule. J.Am.Chem.Soc., 127, 2005
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2F3W
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![BU of 2f3w by Molmil](/molmil-images/mine/2f3w) | solution structure of 1-110 fragment of staphylococcal nuclease in 2M TMAO | Descriptor: | Thermonuclease | Authors: | Liu, D, Xie, T, Feng, Y, Shan, L, Ye, K, Wang, J. | Deposit date: | 2005-11-22 | Release date: | 2006-12-05 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Folding stability and cooperativity of the three forms of 1-110 residues fragment of staphylococcal nuclease Biophys.J., 92, 2007
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2JYF
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1IG9
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![BU of 1ig9 by Molmil](/molmil-images/mine/1ig9) | Structure of the Replicating Complex of a Pol Alpha Family DNA Polymerase | Descriptor: | 5'-D(*AP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*(DOC))-3', CALCIUM ION, ... | Authors: | Franklin, M.C, Wang, J, Steitz, T.A. | Deposit date: | 2001-04-17 | Release date: | 2001-06-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the Replicating Complex of a Pol Alpha Family DNA Polymerase Cell(Cambridge,Mass.), 105, 2001
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3Q2J
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![BU of 3q2j by Molmil](/molmil-images/mine/3q2j) | Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa Protein Kinase Inhibitor CKI-7 Complex | Descriptor: | Aminoglycoside 3'-phosphotransferase, CALCIUM ION, N-(2-AMINOETHYL)-5-CHLOROISOQUINOLINE-8-SULFONAMIDE | Authors: | Fong, D.H, Xiong, B, Hwang, J, Berghuis, A.M. | Deposit date: | 2010-12-20 | Release date: | 2011-05-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1501 Å) | Cite: | Crystal structures of two aminoglycoside kinases bound with a eukaryotic protein kinase inhibitor. Plos One, 6, 2011
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1OSZ
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![BU of 1osz by Molmil](/molmil-images/mine/1osz) | MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND AN (L4V) MUTANT OF THE VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN | Descriptor: | BETA-2 MICROGLOBULIN, MHC CLASS I H-2KB HEAVY CHAIN, VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN | Authors: | Ghendler, Y, Teng, M.-K, Liu, J.-H, Witte, T, Liu, J, Kim, K.S, Kern, P, Chang, H.-C, Wang, J.-H, Reinherz, E.L. | Deposit date: | 1998-06-18 | Release date: | 1999-01-13 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Differential thymic selection outcomes stimulated by focal structural alteration in peptide/major histocompatibility complex ligands. Proc.Natl.Acad.Sci.USA, 95, 1998
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1YWN
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![BU of 1ywn by Molmil](/molmil-images/mine/1ywn) | Vegfr2 in complex with a novel 4-amino-furo[2,3-d]pyrimidine | Descriptor: | N-{4-[4-AMINO-6-(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-5-YL]PHENYL}-N'-[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]UREA, Vascular endothelial growth factor receptor 2 | Authors: | Miyazaki, Y, Matsunaga, S, Tang, J, Maeda, Y, Nakano, M, Philippe, R.J, Shibahara, M, Liu, W, Sato, H, Wang, L, Nolte, R.T. | Deposit date: | 2005-02-18 | Release date: | 2005-08-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Novel 4-amino-furo[2,3-d]pyrimidines as Tie-2 and VEGFR2 dual inhibitors Bioorg.Med.Chem.Lett., 15, 2005
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2JZI
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![BU of 2jzi by Molmil](/molmil-images/mine/2jzi) | |
2HR9
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![BU of 2hr9 by Molmil](/molmil-images/mine/2hr9) | |
3C7N
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![BU of 3c7n by Molmil](/molmil-images/mine/3c7n) | Structure of the Hsp110:Hsc70 Nucleotide Exchange Complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CHLORIDE ION, ... | Authors: | Schuermann, J.P, Jiang, J, Hart, P.J, Sousa, R. | Deposit date: | 2008-02-07 | Release date: | 2008-05-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.115 Å) | Cite: | Structure of the Hsp110:Hsc70 nucleotide exchange machine Mol.Cell, 31, 2008
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3CCN
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![BU of 3ccn by Molmil](/molmil-images/mine/3ccn) | X-ray structure of c-Met with triazolopyridazine inhibitor. | Descriptor: | 4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]phenol, Hepatocyte growth factor receptor | Authors: | Abrecht, B.K, Harmange, J.-C, Bauer, D, Dussault, I, long, A, Bellon, S.F. | Deposit date: | 2008-02-26 | Release date: | 2008-04-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase. J.Med.Chem., 51, 2008
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2F5Z
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![BU of 2f5z by Molmil](/molmil-images/mine/2f5z) | Crystal Structure of Human Dihydrolipoamide Dehydrogenase (E3) Complexed to the E3-Binding Domain of Human E3-Binding Protein | Descriptor: | Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, Pyruvate dehydrogenase protein X component, ... | Authors: | Brautigam, C.A, Chuang, J.L, Wynn, R.M, Tomchick, D.R, Machius, M, Chuang, D.T. | Deposit date: | 2005-11-28 | Release date: | 2006-01-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Structural Insight into Interactions between Dihydrolipoamide Dehydrogenase (E3) and E3 Binding Protein of Human Pyruvate Dehydrogenase Complex. Structure, 14, 2006
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2F3V
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![BU of 2f3v by Molmil](/molmil-images/mine/2f3v) | Solution structure of 1-110 fragment of staphylococcal nuclease with V66W mutation | Descriptor: | Thermonuclease | Authors: | Liu, D, Xie, T, Feng, Y, Shan, L, Ye, K, Wang, J. | Deposit date: | 2005-11-22 | Release date: | 2006-12-05 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Folding stability and cooperativity of the three forms of 1-110 residues fragment of staphylococcal nuclease Biophys.J., 92, 2007
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