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PDB: 36 results
4ZHL
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BU of 4zhl by Molmil
The crystal structure of mupain-1-IG in complex with murinised human uPA at pH7.4
Descriptor: Urokinase-type plasminogen activator, mupain-1-IG
Authors:Jiang, L, Andreasen, P.A, Huang, M.
Deposit date:2015-04-25
Release date:2015-09-16
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Selection of High-Affinity Peptidic Serine Protease Inhibitors with Increased Binding Entropy from a Back-Flip Library of Peptide-Protease Fusions.
J.Mol.Biol., 427, 2015
4DVB
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BU of 4dvb by Molmil
The crystal structure of the Fab fragment of pro-uPA antibody mAb-112
Descriptor: Fab fragment of pro-uPA antibody mAb-112, SULFATE ION, TETRAETHYLENE GLYCOL
Authors:Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M.
Deposit date:2012-02-23
Release date:2013-01-16
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Rezymogenation of active urokinase induced by an inhibitory antibody.
Biochem.J., 449, 2013
3UT3
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BU of 3ut3 by Molmil
A novel PAI-I inhibitor and its structural mechanism
Descriptor: 2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione, Plasminogen activator inhibitor 1
Authors:Lin, Z.H, Hong, Z.B, Shi, X.L, Hu, L.H, Andreasen, P.A, Huang, M.D.
Deposit date:2011-11-25
Release date:2013-02-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:A novel PAI-I inhibitor and its structural mechanism
To be Published
4ZKO
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BU of 4zko by Molmil
The crystal structure of upain-1-W3A in complex with uPA at pH7.4
Descriptor: C-terminal fragment of upain-1-W3A, HEXAETHYLENE GLYCOL, N-terminal fragment of upain-1-W3A, ...
Authors:Jiang, L, Andreasen, P.A, Huang, M.
Deposit date:2015-04-30
Release date:2016-05-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:The crystal structure of mupain-1-IG in complex with murinised human uPA at pH7.4
To Be Published
4DW2
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BU of 4dw2 by Molmil
The crystal structure of uPA in complex with the Fab fragment of mAb-112
Descriptor: Fab fragment of pro-uPA antibody mAb-112, SULFATE ION, Urokinase-type plasminogen activator
Authors:Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M.
Deposit date:2012-02-24
Release date:2013-01-16
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Rezymogenation of active urokinase induced by an inhibitory antibody.
Biochem.J., 449, 2013
4ZKR
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BU of 4zkr by Molmil
The crystal structure of upain-1-W3A in complex with uPA at pH9.0
Descriptor: HEXAETHYLENE GLYCOL, SULFATE ION, Urokinase-type plasminogen activator, ...
Authors:Jiang, L, Andreasen, P.A, Huang, M.
Deposit date:2015-04-30
Release date:2016-05-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:The crystal structure of mupain-1-IG in complex with murinised human uPA at pH7.4
To Be Published
4ZKS
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BU of 4zks by Molmil
The crystal structure of upain-1-W3A in complex with inactive uPA (uPA-S195A) at pH7.4
Descriptor: Urokinase-type plasminogen activator, upain-1-W3A
Authors:Jiang, L, Andreasen, P.A, Huang, M.
Deposit date:2015-04-30
Release date:2016-05-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The crystal structure of mupain-1-IG in complex with murinised human uPA at pH7.4
To Be Published
4ZKN
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BU of 4zkn by Molmil
The crystal structure of upain-1-W3A in complex with uPA at pH5.5
Descriptor: SULFATE ION, TETRAETHYLENE GLYCOL, Urokinase-type plasminogen activator, ...
Authors:Jiang, L, Andreasen, P.A, Huang, M.
Deposit date:2015-04-30
Release date:2016-05-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:The crystal structure of mupain-1-IG in complex with murinised human uPA at pH7.4
To Be Published
4DVA
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BU of 4dva by Molmil
The crystal structure of human urokinase-type plasminogen activator catalytic domain
Descriptor: HEXAETHYLENE GLYCOL, SULFATE ION, Urokinase-type plasminogen activator
Authors:Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M.
Deposit date:2012-02-23
Release date:2013-01-16
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Rezymogenation of active urokinase induced by an inhibitory antibody
Biochem.J., 449, 2013
2NWN
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BU of 2nwn by Molmil
New Pharmacophore for Serine Protease Inhibition Revealed by Crystal Structure of Human Urokinase-type Plasminogen Activator Complexed with a Cyclic Peptidyl Inhibitor, upain-1
Descriptor: Plasminogen activator, urokinase, upain-1
Authors:Zhao, G, Yuan, C, Wind, T, Andreasen, P.A, Huang, Z, Huang, M, Structural Genomics Consortium (SGC)
Deposit date:2006-11-16
Release date:2007-10-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis of specificity of a peptidyl urokinase inhibitor, upain-1
J.Struct.Biol., 160, 2007
4XSK
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BU of 4xsk by Molmil
Structure of PAItrap, an uPA mutant
Descriptor: GLYCEROL, SULFATE ION, TRIETHYLENE GLYCOL, ...
Authors:Gong, L, Proulle, V, Hong, Z, Lin, Z, Liu, M, Yuan, C, Lin, L, Furie, B, Flaumenhaft, R, Andreasen, P, Furie, B, Huang, M.
Deposit date:2015-01-22
Release date:2016-02-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of PAItrap, an uPA mutant
To Be Published
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