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PDB: 60 results

2NWN
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BU of 2nwn by Molmil
New Pharmacophore for Serine Protease Inhibition Revealed by Crystal Structure of Human Urokinase-type Plasminogen Activator Complexed with a Cyclic Peptidyl Inhibitor, upain-1
Descriptor: Plasminogen activator, urokinase, upain-1
Authors:Zhao, G, Yuan, C, Wind, T, Andreasen, P.A, Huang, Z, Huang, M, Structural Genomics Consortium (SGC)
Deposit date:2006-11-16
Release date:2007-10-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis of specificity of a peptidyl urokinase inhibitor, upain-1
J.Struct.Biol., 160, 2007
4ZKR
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BU of 4zkr by Molmil
The crystal structure of upain-1-W3A in complex with uPA at pH9.0
Descriptor: HEXAETHYLENE GLYCOL, SULFATE ION, Urokinase-type plasminogen activator, ...
Authors:Jiang, L, Andreasen, P.A, Huang, M.
Deposit date:2015-04-30
Release date:2016-05-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:The crystal structure of mupain-1-IG in complex with murinised human uPA at pH7.4
To Be Published
4ZKS
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BU of 4zks by Molmil
The crystal structure of upain-1-W3A in complex with inactive uPA (uPA-S195A) at pH7.4
Descriptor: Urokinase-type plasminogen activator, upain-1-W3A
Authors:Jiang, L, Andreasen, P.A, Huang, M.
Deposit date:2015-04-30
Release date:2016-05-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The crystal structure of mupain-1-IG in complex with murinised human uPA at pH7.4
To Be Published
4ZKN
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BU of 4zkn by Molmil
The crystal structure of upain-1-W3A in complex with uPA at pH5.5
Descriptor: SULFATE ION, TETRAETHYLENE GLYCOL, Urokinase-type plasminogen activator, ...
Authors:Jiang, L, Andreasen, P.A, Huang, M.
Deposit date:2015-04-30
Release date:2016-05-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:The crystal structure of mupain-1-IG in complex with murinised human uPA at pH7.4
To Be Published
4DW2
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BU of 4dw2 by Molmil
The crystal structure of uPA in complex with the Fab fragment of mAb-112
Descriptor: Fab fragment of pro-uPA antibody mAb-112, SULFATE ION, Urokinase-type plasminogen activator
Authors:Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M.
Deposit date:2012-02-24
Release date:2013-01-16
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Rezymogenation of active urokinase induced by an inhibitory antibody.
Biochem.J., 449, 2013
4DVA
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BU of 4dva by Molmil
The crystal structure of human urokinase-type plasminogen activator catalytic domain
Descriptor: HEXAETHYLENE GLYCOL, SULFATE ION, Urokinase-type plasminogen activator
Authors:Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M.
Deposit date:2012-02-23
Release date:2013-01-16
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Rezymogenation of active urokinase induced by an inhibitory antibody
Biochem.J., 449, 2013
3OY5
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BU of 3oy5 by Molmil
The crystal structure of uPA complex with peptide inhibitor MH027 at pH7.4
Descriptor: MH027, SULFATE ION, Urokinase-type plasminogen activator
Authors:Jiang, L.G, Andreasen, P.A, Huang, M.D.
Deposit date:2010-09-22
Release date:2011-08-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:The binding mechanism of a peptidic cyclic serine protease inhibitor
J.Mol.Biol., 412, 2011
3OX7
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BU of 3ox7 by Molmil
The crystal structure of uPA complex with peptide inhibitor MH027 at pH4.6
Descriptor: MH027, SULFATE ION, TETRAETHYLENE GLYCOL, ...
Authors:Jiang, L.G, Andreasen, P.A, Huang, M.D.
Deposit date:2010-09-21
Release date:2011-08-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:The binding mechanism of a peptidic cyclic serine protease inhibitor
J.Mol.Biol., 412, 2011
3OY6
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BU of 3oy6 by Molmil
The crystal structure of uPA complex with peptide inhibitor MH036 at pH4.6
Descriptor: MH036, Urokinase-type plasminogen activator
Authors:Jiang, L.G, Andreasen, P.A, Huang, M.D.
Deposit date:2010-09-22
Release date:2011-08-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:The binding mechanism of a peptidic cyclic serine protease inhibitor
J.Mol.Biol., 412, 2011
3M61
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BU of 3m61 by Molmil
Crystal structure of complex of urokinase and a upain-1 variant(W3A) in pH4.6 condition
Descriptor: Urokinase-type plasminogen activator, upain-1 W3A
Authors:Jiang, L, Yuan, C, Wind, T, Andreasen, P.A, Chen, L, Meehan, E.J, Huang, M.
Deposit date:2010-03-15
Release date:2010-04-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystal structure of complex of urokinase and a upain-1 variant(W3A) in pH4.6 condition
TO BE PUBLISHED
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