2NWN
| New Pharmacophore for Serine Protease Inhibition Revealed by Crystal Structure of Human Urokinase-type Plasminogen Activator Complexed with a Cyclic Peptidyl Inhibitor, upain-1 | Descriptor: | Plasminogen activator, urokinase, upain-1 | Authors: | Zhao, G, Yuan, C, Wind, T, Andreasen, P.A, Huang, Z, Huang, M, Structural Genomics Consortium (SGC) | Deposit date: | 2006-11-16 | Release date: | 2007-10-16 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural basis of specificity of a peptidyl urokinase inhibitor, upain-1 J.Struct.Biol., 160, 2007
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4ZKR
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4ZKS
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4ZKN
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4DW2
| The crystal structure of uPA in complex with the Fab fragment of mAb-112 | Descriptor: | Fab fragment of pro-uPA antibody mAb-112, SULFATE ION, Urokinase-type plasminogen activator | Authors: | Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M. | Deposit date: | 2012-02-24 | Release date: | 2013-01-16 | Method: | X-RAY DIFFRACTION (2.97 Å) | Cite: | Rezymogenation of active urokinase induced by an inhibitory antibody. Biochem.J., 449, 2013
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4DVA
| The crystal structure of human urokinase-type plasminogen activator catalytic domain | Descriptor: | HEXAETHYLENE GLYCOL, SULFATE ION, Urokinase-type plasminogen activator | Authors: | Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M. | Deposit date: | 2012-02-23 | Release date: | 2013-01-16 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Rezymogenation of active urokinase induced by an inhibitory antibody Biochem.J., 449, 2013
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3OY5
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3OX7
| The crystal structure of uPA complex with peptide inhibitor MH027 at pH4.6 | Descriptor: | MH027, SULFATE ION, TETRAETHYLENE GLYCOL, ... | Authors: | Jiang, L.G, Andreasen, P.A, Huang, M.D. | Deposit date: | 2010-09-21 | Release date: | 2011-08-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | The binding mechanism of a peptidic cyclic serine protease inhibitor J.Mol.Biol., 412, 2011
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3OY6
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3M61
| Crystal structure of complex of urokinase and a upain-1 variant(W3A) in pH4.6 condition | Descriptor: | Urokinase-type plasminogen activator, upain-1 W3A | Authors: | Jiang, L, Yuan, C, Wind, T, Andreasen, P.A, Chen, L, Meehan, E.J, Huang, M. | Deposit date: | 2010-03-15 | Release date: | 2010-04-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Crystal structure of complex of urokinase and a upain-1 variant(W3A) in pH4.6 condition TO BE PUBLISHED
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