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PDB: 114 件

7Q61
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Structure of TEV conjugated A2ML1 (A2ML1-TC)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin-like protein 1
著者Nielsen, N.S, Zarantonello, A, Andersen, G.R.
登録日2021-11-05
公開日2022-04-20
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family.
Nat Commun, 13, 2022
7Q5Z
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Cryo-EM structure of native human A2ML1
分子名称: Alpha-2-macroglobulin-like protein 1
著者Zarantonello, A, Nielsen, N.S, Andersen, G.R.
登録日2021-11-05
公開日2022-04-20
最終更新日2022-11-02
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family.
Nat Commun, 13, 2022
7Q6C
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complement C6 FIM1-2 bound to CP010 antibody
分子名称: ACETATE ION, CP010 heavy chain, CP010 light chain, ...
著者Olesen, H.G, Andersen, G.R.
登録日2021-11-06
公開日2022-05-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.29274 Å)
主引用文献Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex.
J Innate Immun, 2022
6RU3
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Crystal structure of the FP specific nanobody hFPNb1
分子名称: hFP1Nb1
著者Mazarakis, S.M.M, Pedersen, D.V, Laursen, N.S, Andersen, G.R.
登録日2019-05-27
公開日2019-08-21
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Front Immunol, 10, 2019
6RU5
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human complement C3 in complex with the hC3Nb1 nanobody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Jensen, R.K, Andersen, G.R.
登録日2019-05-27
公開日2019-08-21
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Front Immunol, 10, 2019
6RUV
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Structure of the SCIN stabilized C3bBb convertase bound to Properdin and a the non-inhibitory nanobody hFPNb1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, ...
著者Pedersen, D.V, Andersen, G.R.
登録日2019-05-29
公開日2019-08-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (6.15 Å)
主引用文献Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Front Immunol, 10, 2019
1U2R
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Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE, ...
著者Jorgensen, R, Yates, S.P, Nilsson, J, Prentice, G.A, Teal, D.J, Merrill, A.R, Andersen, G.R.
登録日2004-07-20
公開日2004-09-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae
J.Biol.Chem., 279, 2004
5NQW
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IgE-Fc in complex with single domain antibody 026
分子名称: 026, GLYCEROL, Immunoglobulin heavy constant epsilon, ...
著者Laursen, N.S, Jabs, F, Spillner, E, Andersen, G.R.
登録日2017-04-21
公開日2018-01-17
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts Fc epsilon RI interaction.
Nat Commun, 9, 2018
3CU7
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Human Complement Component 5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ...
著者Fredslund, F, Andersen, G.R.
登録日2008-04-16
公開日2008-06-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.105 Å)
主引用文献Structure of and influence of a tick complement inhibitor on human complement component 5
Nat.Immunol., 9, 2008
6RUS
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Structure of a functional properdin monomer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Properdin, SULFATE ION, ...
著者Pedersen, D.V, Andersen, G.R.
登録日2019-05-29
公開日2019-08-21
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Front Immunol, 10, 2019
5O8W
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CRYSTAL STRUCTURE ANALYSIS OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA
分子名称: Elongation factor 1-alpha, Elongation factor 1-beta, GLUTAMINE, ...
著者Wirth, C, Andersen, G.R, Hunte, C.
登録日2017-06-14
公開日2017-08-23
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A.
J. Biol. Chem., 292, 2017
1PBU
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Solution structure of the C-terminal domain of the human eEF1Bgamma subunit
分子名称: Elongation factor 1-gamma
著者Vanwetswinkel, S, Kriek, J, Andersen, G.R, Guntert, P, Dijk, J, Canters, G.W, Siegal, G.
登録日2003-05-15
公開日2003-07-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献1H, (15)N and (13)C resonance assignments of the highly conserved 19 kDa C-terminal domain from human Elongation Factor 1Bgamma.
J.Biomol.Nmr, 26, 2003
1PAQ
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CRYSTAL STRUCTURE OF THE CATALYTIC FRAGMENT OF EUKARYOTIC INITIATION FACTOR 2B EPSILON
分子名称: Translation initiation factor eIF-2B epsilon subunit
著者Boesen, T, Andersen, G.R, Pavitt, G.D.
登録日2003-05-14
公開日2004-02-10
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the catalytic fragment of translation initiation factor 2B and identification of a critically important catalytic residue.
J.Biol.Chem., 279, 2004
1NHY
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Crystal Structure of the GST-like Domain of Elongation Factor 1-gamma from Saccharomyces cerevisiae.
分子名称: Elongation factor 1-gamma 1, SULFATE ION
著者Jeppesen, M.G, Ortiz, P, Kinzy, T.G, Andersen, G.R, Nyborg, J.
登録日2002-12-20
公開日2003-01-14
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Crystal Structure of the Glutathione S-Transferase-like Domain of Elongation Factor 1B{gamma} from Saccharomyces cerevisiae.
J.Biol.Chem., 278, 2003

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件を2024-10-30に公開中

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