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PDB: 67 件

2AH2
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Trypanosoma cruzi trans-sialidase in complex with 2,3-difluorosialic acid (covalent intermediate)
分子名称: 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, CHLORIDE ION, GLYCEROL, ...
著者Amaya, M.F, Watts, A.G, Damager, I, Wehenkel, A, Nguyen, T, Buschiazzo, A, Paris, G, Frasch, A.C, Withers, S.G, Alzari, P.M.
登録日2005-07-27
公開日2005-08-23
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase
Structure, 12, 2004
3TZD
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Crystal structure of the complex of Human Chromobox Homolog 3 (CBX3)
分子名称: Chromobox protein homolog 3, Histone H1.4
著者Amaya, M.F, Ravichandran, M, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2011-09-27
公開日2012-03-07
最終更新日2013-01-23
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural basis of the chromodomain of Cbx3 bound to methylated peptides from histone h1 and G9a.
Plos One, 7, 2012
4H12
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The crystal structure of methyltransferase domain of human SET domain-containing protein 2 in complex with S-adenosyl-L-homocysteine
分子名称: CHLORIDE ION, Histone-lysine N-methyltransferase SETD2, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Amaya, M.F, Dong, A, Zeng, H, Mackenzie, F, Bunnage, M, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC)
登録日2012-09-10
公開日2012-10-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Sinefungin Derivatives as Inhibitors and Structure Probes of Protein Lysine Methyltransferase SETD2.
J.Am.Chem.Soc., 134, 2012
1S0I
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Trypanosoma cruzi trans-sialidase in complex with sialyl-lactose (Michaelis complex)
分子名称: N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, trans-sialidase
著者Amaya, M.F, Watts, A.G, Damager, I, Wehenkel, A, Nguyen, T, Buschiazzo, A, Paris, G, Frasch, A.C, Withers, S.G, Alzari, P.M.
登録日2003-12-31
公開日2004-05-18
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase.
Structure, 12, 2004
1S0J
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Trypanosoma cruzi trans-sialidase in complex with MuNANA (Michaelis complex)
分子名称: 4-METHYL-2-OXO-2H-CHROMEN-7-YL 5-(ACETYLAMINO)-3,5-DIDEOXY-L-ERYTHRO-NON-2-ULOPYRANOSIDONIC ACID, trans-sialidase
著者Amaya, M.F, Watts, A.G, Damager, I, Wehenkel, A, Nguyen, T, Buschiazzo, A, Paris, G, Frasch, A.C, Withers, S.G, Alzari, P.M.
登録日2003-12-31
公開日2004-05-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase.
Structure, 12, 2004
3I90
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Crystal structure of human chromobox homolog 6 (CBX6) with H3K27 peptide
分子名称: Chromobox protein homolog 6, H3K27 peptide
著者Amaya, M.F, Ravichandran, M, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2009-07-10
公開日2009-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Recognition and specificity determinants of the human cbx chromodomains.
J.Biol.Chem., 286, 2011
3I91
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Crystal structure of human chromobox homolog 8 (CBX8) with H3K9 peptide
分子名称: Chromobox protein homolog 8, H3K9 peptide
著者Amaya, M.F, Ravichandran, M, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2009-07-10
公開日2009-09-08
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Recognition and specificity determinants of the human cbx chromodomains.
J.Biol.Chem., 286, 2011
3H91
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Crystal structure of the complex of human chromobox homolog 2 (CBX2) and H3K27 peptide
分子名称: Chromobox protein homolog 2, H3K27 peptide
著者Amaya, M.F, Ravichandran, M, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2009-04-29
公開日2009-08-18
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Recognition and specificity determinants of the human cbx chromodomains.
J.Biol.Chem., 286, 2011
2A75
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Trypanosoma rangeli Sialidase In Complex With 2,3- Difluorosialic Acid (Covalent Intermediate)
分子名称: 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, SULFATE ION, sialidase
著者Amaya, M.F, Alzari, P.M, Buschiazzo, A.
登録日2005-07-04
公開日2005-11-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and Kinetic Analysis of Two Covalent Sialosyl-Enzyme Intermediates on Trypanosoma rangeli Sialidase.
J.Biol.Chem., 281, 2006
2AGS
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Trypanosoma rangeli Sialidase in Complex with 2-Keto-3-deoxy-D-glycero-D-galacto-2,3-difluoro-nononic acid (2,3-difluoro-KDN)
分子名称: 3-deoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, SULFATE ION, sialidase
著者Amaya, M.F, Alzari, P.M, Buschiazzo, A.
登録日2005-07-27
公開日2005-11-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and Kinetic Analysis of Two Covalent Sialosyl-Enzyme Intermediates on Trypanosoma rangeli Sialidase.
J.Biol.Chem., 281, 2006
1N1Y
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Trypanosoma rangeli sialidase in complex with sialic acid
分子名称: N-acetyl-alpha-neuraminic acid, Sialidase
著者Amaya, M.F, Buschiazzo, A, Nguyen, T, Alzari, P.M.
登録日2002-10-21
公開日2003-01-07
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The high resolution structures of free and inhibitor-bound Trypanosoma rangeli sialidase and its comparison with T. cruzi trans-sialidase
J.Mol.Biol., 325, 2003
1N1S
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Trypanosoma rangeli sialidase
分子名称: SULFATE ION, Sialidase
著者Amaya, M.F, Buschiazzo, A, Nguyen, T, Alzari, P.M.
登録日2002-10-20
公開日2003-01-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献The high resolution structures of free and inhibitor-bound Trypanosoma rangeli sialidase and its comparison with T. cruzi trans-sialidase
J.Mol.Biol., 325, 2003
1N1V
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Trypanosoma rangeli sialidase in complex with DANA
分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, SULFATE ION, Sialidase
著者Amaya, M.F, Buschiazzo, A, Nguyen, T, Alzari, P.M.
登録日2002-10-21
公開日2003-01-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The high resolution structures of free and inhibitor-bound Trypanosoma rangeli sialidase and its comparison with T. cruzi trans-sialidase
J.Mol.Biol., 325, 2003
1N1T
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Trypanosoma rangeli sialidase in complex with DANA at 1.6 A
分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, SULFATE ION, Sialidase
著者Amaya, M.F, Buschiazzo, A, Nguyen, T, Alzari, P.M.
登録日2002-10-20
公開日2003-01-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The high resolution structures of free and inhibitor-bound Trypanosoma rangeli sialidase and its comparison with T. cruzi trans-sialidase
J.Mol.Biol., 325, 2003
3FDT
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Crystal structure of the complex of human chromobox homolog 5 (CBX5) with H3K9(me)3 peptide
分子名称: Chromobox protein homolog 5, H3K9(me)3 peptide
著者Amaya, M.F, Ravichandran, M, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2008-11-26
公開日2009-01-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Recognition and specificity determinants of the human cbx chromodomains.
J.Biol.Chem., 286, 2011
3H8Z
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The Crystal Structure of the Tudor Domains from FXR2
分子名称: Fragile X mental retardation syndrome-related protein 2
著者Amaya, M.F, Dong, A, Adams-Cioaba, M.A, Guo, Y, MacKenzie, F, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2009-04-29
公開日2009-06-16
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2.
Plos One, 5, 2010
2FHR
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Trypanosoma Rangeli Sialidase In Complex With 2,3- Difluorosialic Acid (Covalent Intermediate)
分子名称: 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, GLYCEROL, SULFATE ION, ...
著者Amaya, M.F, Alzari, P.M, Buschiazzo, A.
登録日2005-12-26
公開日2006-01-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and Kinetic Analysis of Two Covalent Sialosyl-Enzyme Intermediates on Trypanosoma rangeli Sialidase.
J.Biol.Chem., 281, 2006
3I8Z
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Crystal structure of human chromobox homolog 4 (CBX4)
分子名称: E3 SUMO-protein ligase CBX4
著者Amaya, M.F, Zhihong, L, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2009-07-10
公開日2009-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Crystal structure of human chromobox homolog 4 (CBX4)
To be Published
3IHO
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The C-terminal glycosylase domain of human MBD4
分子名称: Methyl-CpG-binding domain protein 4
著者Amaya, M.F, Xu, C, Bian, C.B, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2009-07-30
公開日2009-08-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The C-terminal glycosylase domain of human MBD4
To be Published
3IHX
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Methyltransferase domain of human PR domain-containing protein 10
分子名称: PR domain zinc finger protein 10
著者Amaya, M.F, Dombrovski, L, Ni, S, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Min, J, Plotnikov, A.N, Wu, H, Structural Genomics Consortium (SGC)
登録日2009-07-31
公開日2009-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Methyltransferase domain of human PR domain-containing protein 10
To be Published
3I3C
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Crystal Structural of CBX5 Chromo Shadow Domain
分子名称: Chromobox protein homolog 5, SODIUM ION
著者Amaya, M.F, Li, Z, Li, Y, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2009-06-30
公開日2009-08-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Crystal Structural of CBX5 Chromo Shadow Domain
To be Published
3EPP
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Crystal structure of mRNA cap guanine-N7 methyltransferase (RNMT) in complex with sinefungin
分子名称: SINEFUNGIN, mRNA cap guanine-N7 methyltransferase
著者Amaya, M.F, Zeng, H, Loppnau, P, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Min, J, Plotnikov, A.N, Wu, H, Structural Genomics Consortium (SGC)
登録日2008-09-29
公開日2008-10-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Crystal structure of mRNA cap guanine-N7 methyltransferase (RNMT) in complex with sinefungin.
To be Published
3EAE
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PWWP domain of human hepatoma-derived growth factor 2 (HDGF2)
分子名称: Hepatoma-derived growth factor-related protein 2
著者Amaya, M.F, Zeng, H, Mackenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Wu, H, Structural Genomics Consortium (SGC)
登録日2008-08-25
公開日2008-09-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structural and Histone Binding Ability Characterizations of Human PWWP Domains.
Plos One, 6, 2011
3F2K
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Structure of the transposase domain of human Histone-lysine N-methyltransferase SETMAR
分子名称: Histone-lysine N-methyltransferase SETMAR, LYFA Peptide, MAGNESIUM ION
著者Amaya, M.F, Dombrovski, L, Ni, S, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Min, J, Plotnikov, A.N, Wu, H, Structural Genomics Consortium (SGC)
登録日2008-10-29
公開日2008-11-25
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The Crystal Structure of Transposase Domain of Human Histone-lysine N-methyltransferase SETMAR.
To be Published
3F2U
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Crystal structure of human chromobox homolog 1 (CBX1)
分子名称: Chromobox protein homolog 1
著者Amaya, M.F, Ravichandran, M, Tempel, W, Wernimont, A.K, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Botchkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2008-10-30
公開日2008-11-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the complex of human chromobox homolog 1 (CBX1)
To be Published

 

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