1S0J

Trypanosoma cruzi trans-sialidase in complex with MuNANA (Michaelis complex)

Summary for 1S0J

Entry DOI	10.2210/pdb1s0j/pdb
Related	1S0I 1S0K
Descriptor	trans-sialidase, 4-METHYL-2-OXO-2H-CHROMEN-7-YL 5-(ACETYLAMINO)-3,5-DIDEOXY-L-ERYTHRO-NON-2-ULOPYRANOSIDONIC ACID (3 entities in total)
Functional Keywords	transglycosidase, michaelis complex, trypanosoma cruzi, hydrolase
Biological source	Trypanosoma cruzi
Total number of polymer chains	1
Total formula weight	71812.67
Authors	Amaya, M.F.,Watts, A.G.,Damager, I.,Wehenkel, A.,Nguyen, T.,Buschiazzo, A.,Paris, G.,Frasch, A.C.,Withers, S.G.,Alzari, P.M. (deposition date: 2003-12-31, release date: 2004-05-18, Last modification date: 2023-08-23)
Primary citation	Amaya, M.F.,Watts, A.G.,Damager, I.,Wehenkel, A.,Nguyen, T.,Buschiazzo, A.,Paris, G.,Frasch, A.C.,Withers, S.G.,Alzari, P.M. Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase. Structure, 12:775-784, 2004 Cited by PubMed: 15130470 DOI: 10.1016/j.str.2004.02.036 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation