2AGS
Trypanosoma rangeli Sialidase in Complex with 2-Keto-3-deoxy-D-glycero-D-galacto-2,3-difluoro-nononic acid (2,3-difluoro-KDN)
Summary for 2AGS
| Entry DOI | 10.2210/pdb2ags/pdb |
| Related | 1N1S 2A75 |
| Descriptor | sialidase, SULFATE ION, 3-deoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, ... (4 entities in total) |
| Functional Keywords | beta-propeller, covalent enzyme-intermediate complex, beta-sandwich, hydrolase |
| Biological source | Trypanosoma rangeli |
| Total number of polymer chains | 1 |
| Total formula weight | 71683.54 |
| Authors | Amaya, M.F.,Alzari, P.M.,Buschiazzo, A. (deposition date: 2005-07-27, release date: 2005-11-22, Last modification date: 2023-08-23) |
| Primary citation | Watts, A.G.,Oppezzo, P.,Withers, S.G.,Alzari, P.M.,Buschiazzo, A. Structural and Kinetic Analysis of Two Covalent Sialosyl-Enzyme Intermediates on Trypanosoma rangeli Sialidase. J.Biol.Chem., 281:4149-4155, 2006 Cited by PubMed: 16298994DOI: 10.1074/jbc.M510677200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
Download full validation report
