7PD2
 
 | | Crystal structure of the substrate-free radical SAM tyrosine lyase ThiH (2-iminoacetate synthase) from Thermosinus carboxydivorans | | Descriptor: | 5'-DEOXYADENOSINE, GLYCEROL, IRON/SULFUR CLUSTER, ... | | Authors: | Amara, P, Saragaglia, C, Mouesca, J.-M, Martin, L, Nicolet, Y. | | Deposit date: | 2021-08-04 | | Release date: | 2022-05-11 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | L-tyrosine-bound ThiH structure reveals C-C bond break differences within radical SAM aromatic amino acid lyases.
Nat Commun, 13, 2022
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7PD1
 | | Crystal structure of the L-tyrosine-bound radical SAM tyrosine lyase ThiH (2-iminoacetate synthase) from Thermosinus carboxydivorans | | Descriptor: | 5'-DEOXYADENOSINE, BROMIDE ION, GLYCEROL, ... | | Authors: | Amara, P, Saragaglia, C, Mouesca, J.-M, Martin, L, Nicolet, Y. | | Deposit date: | 2021-08-04 | | Release date: | 2022-05-11 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.27 Å) | | Cite: | L-tyrosine-bound ThiH structure reveals C-C bond break differences within radical SAM aromatic amino acid lyases.
Nat Commun, 13, 2022
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6HTM
 | | X-ray structure of the tryptophan lyase NosL in complex with bound tryptamin | | Descriptor: | 2-(1H-INDOL-3-YL)ETHANAMINE, 3-methyl-2-indolic acid synthase, 5'-DEOXYADENOSINE, ... | | Authors: | Amara, P, Mouesca, J.M, Bella, M, Saragaglia, C, Gambarelli, S, Nicolet, Y. | | Deposit date: | 2018-10-04 | | Release date: | 2018-11-21 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Radical S-Adenosyl-l-methionine Tryptophan Lyase (NosL): How the Protein Controls the Carboxyl Radical •CO2-Migration.
J.Am.Chem.Soc., 140, 2018
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6HTO
 | | Tryptophan lyase 'empty state' | | Descriptor: | 3-methyl-2-indolic acid synthase, 5'-DEOXYADENOSINE, CHLORIDE ION, ... | | Authors: | Amara, P, Mouesca, J.M, Bella, M, Martin, L, Saragaglia, C, Gambarelli, S, Nicolet, Y. | | Deposit date: | 2018-10-04 | | Release date: | 2018-11-21 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Radical S-Adenosyl-l-methionine Tryptophan Lyase (NosL): How the Protein Controls the Carboxyl Radical •CO2-Migration.
J.Am.Chem.Soc., 140, 2018
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6HTK
 | | X-ray structure of the tryptophan lyase NosL in complex with (R)-(+)-indoline-2-carboxylate | | Descriptor: | 1H-indole-2-carboxylic acid, 3-methyl-2-indolic acid synthase, 5'-DEOXYADENOSINE, ... | | Authors: | Amara, P, Mouesca, J.M, Bella, M, Martin, L, Saragaglia, C, Gambarelli, S, Nicolet, Y. | | Deposit date: | 2018-10-04 | | Release date: | 2018-11-21 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Radical S-Adenosyl-l-methionine Tryptophan Lyase (NosL): How the Protein Controls the Carboxyl Radical •CO2-Migration.
J.Am.Chem.Soc., 140, 2018
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7BI7
 | | An Unexpected P-Cluster like Intermediate En Route to the Nitrogenase FeMo-co | | Descriptor: | FE(8)-S(7) CLUSTER, FeMo cofactor biosynthesis protein NifB, HYDROSULFURIC ACID, ... | | Authors: | Jenner, L.P, Cherrier, M.V, Amara, P, Rubio, L.M, Nicolet, Y. | | Deposit date: | 2021-01-12 | | Release date: | 2021-03-10 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | An unexpected P-cluster like intermediate en route to the nitrogenase FeMo-co.
Chem Sci, 12, 2021
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4P3X
 | | Structure of the Fe4S4 quinolinate synthase NadA from Thermotoga maritima | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, IRON/SULFUR CLUSTER, Quinolinate synthase A, ... | | Authors: | Cherrier, M.V, Chan, A, Darnault, C, Reichmann, D, Amara, P, Ollagnier de Choudens, S, Fontecilla-Camps, J.C. | | Deposit date: | 2014-03-10 | | Release date: | 2014-04-02 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | The crystal structure of Fe4S4 quinolinate synthase unravels an enzymatic dehydration mechanism that uses tyrosine and a hydrolase-type triad.
J.Am.Chem.Soc., 136, 2014
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3CIX
 | | X-RAY structure of the [FeFe]-hydrogenase maturase HydE from thermotoga maritima in complex with thiocyanate | | Descriptor: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Nicolet, Y, Ruback, J.K, Posewitz, M.C, Amara, P, Mathevon, C, Atta, M, Fontecave, M, Fontecilla-Camps, J.C. | | Deposit date: | 2008-03-12 | | Release date: | 2008-04-08 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | X-ray Structure of the [FeFe]-Hydrogenase Maturase HydE from Thermotoga maritima
J.Biol.Chem., 283, 2008
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3IIZ
 | | X-ray structure of the FeFe-hydrogenase maturase HydE from T. maritima in complex with S-adenosyl-L-methionine | | Descriptor: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Biotin synthetase, putative, ... | | Authors: | Nicolet, Y, Amara, P, Mouesca, J.M, Fontecilla-Camps, J.C. | | Deposit date: | 2009-08-03 | | Release date: | 2009-09-22 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Unexpected electron transfer mechanism upon AdoMet cleavage in radical SAM proteins
Proc.Natl.Acad.Sci.USA, 2009
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3IIX
 | | X-ray structure of the FeFe-hydrogenase maturase HydE from T. maritima in complex with methionine and 5'deoxyadenosine | | Descriptor: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, 5'-DEOXYADENOSINE, CARBONATE ION, ... | | Authors: | Nicolet, Y, Amara, P, Mouesca, J.M, Fontecilla-Camps, J.C. | | Deposit date: | 2009-08-03 | | Release date: | 2009-09-22 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Unexpected electron transfer mechanism upon AdoMet cleavage in radical SAM proteins
Proc.Natl.Acad.Sci.USA, 2009
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4R33
 | | X-ray structure of the tryptophan lyase NosL with Tryptophan and S-adenosyl-L-homocysteine bound | | Descriptor: | CHLORIDE ION, GLYCEROL, IRON/SULFUR CLUSTER, ... | | Authors: | Nicolet, Y, Zeppieri, L, Amara, P, Fontecilla-Camps, J.-C. | | Deposit date: | 2014-08-14 | | Release date: | 2014-09-17 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Crystal Structure of Tryptophan Lyase (NosL): Evidence for Radical Formation at the Amino Group of Tryptophan.
Angew.Chem.Int.Ed.Engl., 53, 2014
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4R34
 | | X-ray structure of the tryptophan lyase NosL with Tryptophan, 5'-deoxyadenosine and methionine bound | | Descriptor: | 5'-DEOXYADENOSINE, BROMIDE ION, GLYCEROL, ... | | Authors: | Nicolet, Y, Zeppieri, L, Amara, P, Fontecilla-Camps, J.-C. | | Deposit date: | 2014-08-14 | | Release date: | 2014-09-17 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structure of Tryptophan Lyase (NosL): Evidence for Radical Formation at the Amino Group of Tryptophan.
Angew.Chem.Int.Ed.Engl., 53, 2014
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3CIW
 | | X-RAY structure of the [FeFe]-hydrogenase maturase HydE from thermotoga maritima | | Descriptor: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CHLORIDE ION, FeFe-Hydrogenase maturase, ... | | Authors: | Nicolet, Y, Ruback, J.K, Posewitz, M.C, Amara, P, Mathevon, C, Atta, M, Fontecave, M, Fontecilla-Camps, J.C. | | Deposit date: | 2008-03-12 | | Release date: | 2008-04-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | X-ray Structure of the [FeFe]-Hydrogenase Maturase HydE from Thermotoga maritima
J.Biol.Chem., 283, 2008
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4RTB
 | | X-ray structure of the FeFe-hydrogenase maturase HydG from Carboxydothermus hydrogenoformans | | Descriptor: | CHLORIDE ION, HydG protein, IRON/SULFUR CLUSTER, ... | | Authors: | Nicolet, Y, Pagnier, A, Zeppieri, L, Martin, L, Amara, P, Fontecilla-Camps, J.C. | | Deposit date: | 2014-11-14 | | Release date: | 2015-01-28 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Crystal Structure of HydG from Carboxydothermus hydrogenoformans: A Trifunctional [FeFe]-Hydrogenase Maturase.
Chembiochem, 16, 2015
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2JI1
 | | X-ray structure of wild-type superoxide reductase from Desulfoarculus baarsii | | Descriptor: | CALCIUM ION, Desulfoferrodoxin, FE (II) ION, ... | | Authors: | Katona, G, Carpentier, P, Niviere, V, Amara, P, Adam, V, Ohana, J, Tsanov, N, Bourgeois, D. | | Deposit date: | 2007-02-24 | | Release date: | 2007-05-01 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Raman-assisted crystallography reveals end-on peroxide intermediates in a nonheme iron enzyme.
Science, 316, 2007
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2JI3
 | | X-ray structure of the iron-peroxide intermediate of superoxide reductase (E114A mutant) from Desulfoarculus baarsii | | Descriptor: | CALCIUM ION, Desulfoferrodoxin, FE (III) ION, ... | | Authors: | Katona, G, Carpentier, P, Niviere, V, Amara, P, Adam, V, Ohana, J, Tsanov, N, Bourgeois, D. | | Deposit date: | 2007-02-24 | | Release date: | 2007-05-01 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Raman-assisted crystallography reveals end-on peroxide intermediates in a nonheme iron enzyme.
Science, 316, 2007
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2JI2
 | | X-ray structure of E114A mutant of superoxide reductase from Desulfoarculus baarsii in the native, reduced form | | Descriptor: | CALCIUM ION, Desulfoferrodoxin, FE (II) ION, ... | | Authors: | Katona, G, Carpentier, P, Niviere, V, Amara, P, Adam, V, Ohana, J, Tsanov, N, Bourgeois, D. | | Deposit date: | 2007-02-24 | | Release date: | 2007-05-01 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Raman-assisted crystallography reveals end-on peroxide intermediates in a nonheme iron enzyme.
Science, 316, 2007
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6FD2
 | | Radical SAM 1,2-diol dehydratase AprD4 in complex with its substrate paromamine | | Descriptor: | 5'-DEOXYADENOSINE, IRON/SULFUR CLUSTER, METHIONINE, ... | | Authors: | Liu, W.Q, Amara, P, Mouesca, J.M, Ji, X, Renoux, O, Martin, L, Zhang, C, Zhang, Q, Nicolet, Y. | | Deposit date: | 2017-12-21 | | Release date: | 2018-01-17 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | 1,2-Diol Dehydration by the Radical SAM Enzyme AprD4: A Matter of Proton Circulation and Substrate Flexibility.
J. Am. Chem. Soc., 140, 2018
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4EB5
 | | A. fulgidus IscS-IscU complex structure | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, ... | | Authors: | Marinoni, E.N, de Oliveira, J.S, Nicolet, Y, Raulfs, E.C, Amara, P, Dean, D.R, Fontecilla-Camps, J.C. | | Deposit date: | 2012-03-23 | | Release date: | 2012-05-02 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.53 Å) | | Cite: | (IscS-IscU)2 complex structures provide insights into Fe2S2 biogenesis and transfer.
Angew.Chem.Int.Ed.Engl., 51, 2012
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2J5K
 | | 2.0 A resolution structure of the wild type malate dehydrogenase from Haloarcula marismortui (radiation damage series) | | Descriptor: | CHLORIDE ION, MALATE DEHYDROGENASE | | Authors: | Fioravanti, E, Vellieux, F.M.D, Amara, P, Madern, D, Weik, M. | | Deposit date: | 2006-09-18 | | Release date: | 2006-09-21 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Specific Radiation Damage to Acidic Residues and its Relation to Their Chemical and Structural Environment.
J.Synchrotron Radiat., 14, 2007
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2J5R
 | | 2.25 A resolution structure of the wild type malate dehydrogenase from Haloarcula marismortui after second radiation burn (radiation damage series) | | Descriptor: | CHLORIDE ION, MALATE DEHYDROGENASE | | Authors: | Fioravanti, E, Vellieux, F.M.D, Amara, P, Madern, D, Weik, M. | | Deposit date: | 2006-09-19 | | Release date: | 2006-09-25 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Specific Radiation Damage to Acidic Residues and its Relation to Their Chemical and Structural Environment.
J.Synchrotron Radiat., 14, 2007
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2J5Q
 | | 2.15 A resolution structure of the wild type malate dehydrogenase from Haloarcula marismortui after first radiation burn (radiation damage series) | | Descriptor: | CHLORIDE ION, MALATE DEHYDROGENASE | | Authors: | Fioravanti, E, Vellieux, F.M.D, Amara, P, Madern, D, Weik, M. | | Deposit date: | 2006-09-19 | | Release date: | 2006-09-21 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Specific Radiation Damage to Acidic Residues and its Relation to Their Chemical and Structural Environment.
J.Synchrotron Radiat., 14, 2007
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6H8T
 | | Crystal structure of Papain modify by achiral Ru(II)complex | | Descriptor: | ACETATE ION, CHLORIDE ION, Papain, ... | | Authors: | Cherrier, M.V, Amara, P, Talbi, B, Salmin, M, Fontecilla-Camps, J.C. | | Deposit date: | 2018-08-03 | | Release date: | 2018-09-12 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystallographic evidence for unexpected selective tyrosine hydroxylations in an aerated achiral Ru-papain conjugate.
Metallomics, 10, 2018
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4DCY
 | | X-ray structure of NikA in complex with Fe(1S,2S)-N,N-kappa-Bis(2-pyridylmethyl)-N-carboxymethyl-N-kappa-methyl-1,2-cyclohexanediamine | | Descriptor: | ACETATE ION, GLYCEROL, Nickel-binding periplasmic protein, ... | | Authors: | Cherrier, M.V, Girgenti, E, Amara, P, Iannello, M, Marchi-Delapierre, C, Fontecilla-Camps, J.C, Menage, S, Cavazza, C. | | Deposit date: | 2012-01-18 | | Release date: | 2012-05-09 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The structure of the periplasmic nickel-binding protein NikA provides insights for artificial metalloenzyme design.
J.Biol.Inorg.Chem., 17, 2012
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4DCX
 | | X-ray structure of NikA in complex with Fe(1R,2R)-N,N'-Bis(2-pyridylmethyl)-N,N'-dicarboxymethyl-1,2-cyclohexanediamine | | Descriptor: | ACETATE ION, GLYCEROL, Nickel-binding periplasmic protein, ... | | Authors: | Cherrier, M.V, Girgenti, E, Amara, P, Iannello, M, Marchi-Delapierre, C, Fontecilla-Camps, J.C, Menage, S, Cavazza, C. | | Deposit date: | 2012-01-18 | | Release date: | 2012-05-09 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The structure of the periplasmic nickel-binding protein NikA provides insights for artificial metalloenzyme design.
J.Biol.Inorg.Chem., 17, 2012
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