3G5U
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![BU of 3g5u by Molmil](/molmil-images/mine/3g5u) | Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding | Descriptor: | MERCURY (II) ION, Multidrug resistance protein 1a | Authors: | Aller, S.G, Yu, J, Ward, A, Weng, Y, Chittaboina, S, Zhuo, R, Harrell, P.M, Trinh, Y.T, Zhang, Q, Urbatsch, I.L, Chang, G. | Deposit date: | 2009-02-05 | Release date: | 2009-03-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science, 323, 2009
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3G61
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![BU of 3g61 by Molmil](/molmil-images/mine/3g61) | Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding | Descriptor: | (4S,11S,18S)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1a | Authors: | Aller, S.G, Yu, J, Ward, A, Weng, Y, Chittaboina, S, Zhuo, R, Harrell, P.M, Trinh, Y.T, Zhang, Q, Urbatsch, I.L, Chang, G. | Deposit date: | 2009-02-05 | Release date: | 2009-03-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (4.35 Å) | Cite: | Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science, 323, 2009
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3G60
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![BU of 3g60 by Molmil](/molmil-images/mine/3g60) | Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding | Descriptor: | (4R,11R,18R)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1a | Authors: | Aller, S.G, Yu, J, Ward, A, Weng, Y, Chittaboina, S, Zhuo, R, Harrell, P.M, Trinh, Y.T, Zhang, Q, Urbatsch, I.L, Chang, G. | Deposit date: | 2009-02-05 | Release date: | 2009-03-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (4.4 Å) | Cite: | Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science, 323, 2009
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6UJR
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![BU of 6ujr by Molmil](/molmil-images/mine/6ujr) | P-glycoprotein mutant-F724A and C952A-with BDE100 | Descriptor: | 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1 | Authors: | Aller, S.G, Le, C.A. | Deposit date: | 2019-10-03 | Release date: | 2020-05-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein. Iucrj, 7, 2020
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6UJT
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![BU of 6ujt by Molmil](/molmil-images/mine/6ujt) | P-glycoprotein mutant-Y303A and C952A-with BDE100 | Descriptor: | 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1 | Authors: | Aller, S.G, Le, C.A. | Deposit date: | 2019-10-03 | Release date: | 2020-05-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.17 Å) | Cite: | Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein. Iucrj, 7, 2020
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6UJW
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![BU of 6ujw by Molmil](/molmil-images/mine/6ujw) | P-glycoprotein mutant-Y306A and C952A-with BDE100 | Descriptor: | 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1 | Authors: | Aller, S.G, Le, C.A. | Deposit date: | 2019-10-03 | Release date: | 2020-05-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.15 Å) | Cite: | Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein. Iucrj, 7, 2020
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6UJP
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![BU of 6ujp by Molmil](/molmil-images/mine/6ujp) | P-glycoprotein mutant-F979A and C952A-with BDE100 | Descriptor: | 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1 | Authors: | Aller, S.G, Le, C.A. | Deposit date: | 2019-10-03 | Release date: | 2020-05-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.98 Å) | Cite: | Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein. Iucrj, 7, 2020
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6UJN
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![BU of 6ujn by Molmil](/molmil-images/mine/6ujn) | P-glycoprotein mutant-C952A-with BDE100 | Descriptor: | 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1 | Authors: | Aller, S.G, Le, C.A. | Deposit date: | 2019-10-03 | Release date: | 2020-05-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.98 Å) | Cite: | Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein. Iucrj, 7, 2020
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6UJS
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![BU of 6ujs by Molmil](/molmil-images/mine/6ujs) | P-glycoprotein mutant-F728A and C952A-with BDE100 | Descriptor: | 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1 | Authors: | Aller, S.G, Le, C.A. | Deposit date: | 2019-10-03 | Release date: | 2020-05-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.17 Å) | Cite: | Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein. Iucrj, 7, 2020
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7ROQ
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![BU of 7roq by Molmil](/molmil-images/mine/7roq) | Alternative Structure of Human ABCA1 | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Aller, S.G. | Deposit date: | 2021-08-01 | Release date: | 2022-01-19 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Refined ABCA1 with Domain-swapped Regulatory Domains Plos One, 2022
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4M2T
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![BU of 4m2t by Molmil](/molmil-images/mine/4m2t) | Corrected Structure of Mouse P-glycoprotein bound to QZ59-SSS | Descriptor: | (4S,11S,18S)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1A | Authors: | Li, J, Jaimes, K.F, Aller, S.G. | Deposit date: | 2013-08-05 | Release date: | 2013-11-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (4.35 Å) | Cite: | Refined structures of mouse P-glycoprotein. Protein Sci., 23, 2014
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4M1M
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![BU of 4m1m by Molmil](/molmil-images/mine/4m1m) | |
4M2S
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![BU of 4m2s by Molmil](/molmil-images/mine/4m2s) | Corrected Structure of Mouse P-glycoprotein bound to QZ59-RRR | Descriptor: | (4R,11R,18R)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1A | Authors: | Li, J, Jaimes, K.F, Aller, S.G. | Deposit date: | 2013-08-05 | Release date: | 2013-11-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (4.4 Å) | Cite: | Refined structures of mouse P-glycoprotein. Protein Sci., 23, 2014
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6Q1D
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![BU of 6q1d by Molmil](/molmil-images/mine/6q1d) | Holo YfeA reconstituted by zinc soaking | Descriptor: | Periplasmic chelated iron-binding protein YfeA, ZINC ION | Authors: | Radka, C.D, Labiuk, S.L, DeLucas, L.J, Aller, S.G. | Deposit date: | 2019-08-03 | Release date: | 2019-09-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Structures of the substrate-binding protein YfeA in apo and zinc-reconstituted holo forms. Acta Crystallogr D Struct Biol, 75, 2019
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6Q1C
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![BU of 6q1c by Molmil](/molmil-images/mine/6q1c) | |
8TQE
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![BU of 8tqe by Molmil](/molmil-images/mine/8tqe) | XptA2 wild type | Descriptor: | XptA2 | Authors: | Martin, C.L, Binshtein, E.M, Aller, S.G. | Deposit date: | 2023-08-07 | Release date: | 2023-09-27 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structures of the Insecticidal Toxin Complex Subunit XptA2 Highlight Roles for Flexible Domains. Int J Mol Sci, 24, 2023
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8TV0
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![BU of 8tv0 by Molmil](/molmil-images/mine/8tv0) | XptA2 wild type | Descriptor: | XptA2 | Authors: | Martin, C.L, Aller, S.G. | Deposit date: | 2023-08-17 | Release date: | 2023-09-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structures of the Insecticidal Toxin Complex Subunit XptA2 Highlight Roles for Flexible Domains. Int J Mol Sci, 24, 2023
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6B2X
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![BU of 6b2x by Molmil](/molmil-images/mine/6b2x) | Apo YiuA Crystal Form 1 | Descriptor: | CHLORIDE ION, SODIUM ION, Solute-binding periplasmic protein of iron/siderophore ABC transporter | Authors: | Radka, C.D, DeLucas, L.J, Aller, S.G. | Deposit date: | 2017-09-20 | Release date: | 2017-11-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.199 Å) | Cite: | The crystal structure of the Yersinia pestis iron chaperone YiuA reveals a basic triad binding motif for the chelated metal. Acta Crystallogr D Struct Biol, 73, 2017
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6B2Y
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![BU of 6b2y by Molmil](/molmil-images/mine/6b2y) | Apo YiuA Crystal Form 2 | Descriptor: | SODIUM ION, Solute-binding periplasmic protein of iron/siderophore ABC transporter | Authors: | Radka, C.D, DeLucas, L.J, Aller, S.G. | Deposit date: | 2017-09-20 | Release date: | 2017-11-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | The crystal structure of the Yersinia pestis iron chaperone YiuA reveals a basic triad binding motif for the chelated metal. Acta Crystallogr D Struct Biol, 73, 2017
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7ME1
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![BU of 7me1 by Molmil](/molmil-images/mine/7me1) | YfeA oligomer crystal 1, form 1 | Descriptor: | FE (III) ION, MANGANESE (II) ION, Periplasmic chelated iron-binding protein YfeA, ... | Authors: | Radka, C.D, Aller, S.G. | Deposit date: | 2021-04-06 | Release date: | 2021-08-25 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Site 2 of the Yersinia pestis substrate-binding protein YfeA is a dynamic surface metal-binding site. Acta Crystallogr.,Sect.F, 77, 2021
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7ME2
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![BU of 7me2 by Molmil](/molmil-images/mine/7me2) | YfeA oligomer crystal 2, form 2 | Descriptor: | FE (III) ION, MANGANESE (II) ION, Periplasmic chelated iron-binding protein YfeA, ... | Authors: | Radka, C.D, Aller, S.G. | Deposit date: | 2021-04-06 | Release date: | 2021-08-25 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Site 2 of the Yersinia pestis substrate-binding protein YfeA is a dynamic surface metal-binding site Acta Crystallogr.,Sect.F, 77, 2021
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7ME3
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![BU of 7me3 by Molmil](/molmil-images/mine/7me3) | YfeA oligomer crystal 3, form 2 | Descriptor: | FE (III) ION, MANGANESE (II) ION, Periplasmic chelated iron-binding protein YfeA, ... | Authors: | Radka, C.D, Aller, S.G. | Deposit date: | 2021-04-06 | Release date: | 2021-08-25 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Site 2 of the Yersinia pestis substrate-binding protein YfeA is a dynamic surface metal-binding site Acta Crystallogr.,Sect.F, 77, 2021
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5UY0
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![BU of 5uy0 by Molmil](/molmil-images/mine/5uy0) | |
5UYG
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![BU of 5uyg by Molmil](/molmil-images/mine/5uyg) | YfeA with metal bound to site 2 - Zn wavelength | Descriptor: | Periplasmic chelated iron-binding protein YfeA, ZINC ION | Authors: | Radka, C.D, DeLucas, L.J, Aller, S.G. | Deposit date: | 2017-02-24 | Release date: | 2017-07-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.859 Å) | Cite: | Crystal structure of Yersinia pestis virulence factor YfeA reveals two polyspecific metal-binding sites. Acta Crystallogr D Struct Biol, 73, 2017
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5UYC
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![BU of 5uyc by Molmil](/molmil-images/mine/5uyc) | |