2OFF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2off by Molmil](/molmil-images/mine/2off) | The crystal structure of Glycogen Phosphorylase b in complex with a potent allosteric inhibitor | 分子名称: | 2-DEOXY-3,4-BIS-O-[3-(4-HYDROXYPHENYL)PROPANOYL]-L-THREO-PENTARIC ACID, Glycogen phosphorylase, muscle form | 著者 | Tiraidis, C, Alexacou, K.-M, Zographos, S.E, Leonidas, D.D, Gimisis, T, Oikonomakos, N.G. | 登録日 | 2007-01-03 | 公開日 | 2007-08-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | FR258900, a potential anti-hyperglycemic drug, binds at the allosteric site of glycogen phosphorylase Protein Sci., 16, 2007
|
|
2QN3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qn3 by Molmil](/molmil-images/mine/2qn3) | Glycogen Phosphorylase in complex with N-4-chlorobenzoyl-N-beta-D-glucopyranosyl urea | 分子名称: | Glycogen phosphorylase, muscle form, N-{[(4-chlorophenyl)carbonyl]carbamoyl}-beta-D-glucopyranosylamine | 著者 | Chrysina, E.D, Tiraidis, C, Alexacou, K.-M, Zographos, S.E, Leonidas, D.D, Oikonomakos, N.G. | 登録日 | 2007-07-17 | 公開日 | 2008-07-22 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | N-(4-substituted-benzoyl)-N'-(beta-D-glucopyranosyl)ureas, inhibitors of glycogen phosphorylase: synthesis, kinetic and crystallographic evaluation To be Published
|
|
2QN7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qn7 by Molmil](/molmil-images/mine/2qn7) | Glycogen Phosphorylase b in complex with N-4-hydroxybenzoyl-N'-4-beta-D-glucopyranosyl urea | 分子名称: | Glycogen phosphorylase, muscle form, INOSINIC ACID, ... | 著者 | Chrysina, E.D, Tiraidis, K, Alexacou, K.-M, Zographos, S.E, Leonidas, D.D, Oikonomakos, N.G. | 登録日 | 2007-07-18 | 公開日 | 2008-07-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | N-(4-substituted-benzoyl)-N'-(beta-D-glucopyranosyl)ureas, inhibitors of glycogen phosphorylase: synthesis, kinetic and crystallographic evaluation To be Published
|
|
2QLN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qln by Molmil](/molmil-images/mine/2qln) | Glycogen Phosphorylase b in complex with N-4-phenylbenzoyl-N'-beta-D-glucopyranosyl urea | 分子名称: | Glycogen phosphorylase, muscle form, N-[(biphenyl-4-ylcarbonyl)carbamoyl]-beta-D-glucopyranosylamine | 著者 | Oikonomakos, N.G, Chrysina, E.D, Tiraidis, C, Alexacou, K.-M, Leonidas, D.D, Sographos, S.E. | 登録日 | 2007-07-13 | 公開日 | 2008-07-15 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | N-(4-substituted-benzoyl)-N'-(beta-D-glucopyranosyl)ureas, inhibitors of glycogen phosphorylase: synthesis, kinetic and crystallographic evaluation To be Published
|
|
2QN1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qn1 by Molmil](/molmil-images/mine/2qn1) | Glycogen Phosphorylase b in complex with asiatic acid | 分子名称: | Glycogen phosphorylase, muscle form, asiatic acid | 著者 | Zographos, S.E, Leonidas, D.D, Alexacou, K.-M, Hayes, J, Oikonomakos, N.G. | 登録日 | 2007-07-17 | 公開日 | 2008-06-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies J.Med.Chem., 51, 2008
|
|
2QNB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qnb by Molmil](/molmil-images/mine/2qnb) | Glycogen Phosphorylase b in complex with N-benzoyl-N'-beta-D-glucopyranosyl urea | 分子名称: | Glycogen phosphorylase, muscle form, N-[(phenylcarbonyl)carbamoyl]-beta-D-glucopyranosylamine | 著者 | Chrysina, E.D, Tiraidis, C, Alexacou, K.-M, Zographos, S.E, Leonidas, D.D, Oikonomakos, N.G. | 登録日 | 2007-07-18 | 公開日 | 2008-07-22 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | N-(4-substituted-benzoyl)-N'-(beta-D-glucopyranosyl)ureas, inhibitors of glycogen phosphorylase: synthesis, kinetic and crystallographic evaluation To be Published
|
|
2QN9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qn9 by Molmil](/molmil-images/mine/2qn9) | Glycogen Phosphorylase in complex with N-4-aminobenzoyl-N'-beta-D-glucopyranosyl urea | 分子名称: | Glycogen phosphorylase, muscle form, INOSINIC ACID, ... | 著者 | Chrysina, E.D, Tiraidis, C, Alexacou, K.-M, Zographos, S.E, Leonidas, D.D, Oikonomakos, N.G. | 登録日 | 2007-07-18 | 公開日 | 2008-07-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | N-(4-substituted-benzoyl)-N'-(beta-D-glucopyranosyl)ureas, inhibitors of glycogen phosphorylase: synthesis, kinetic and crystallographic evaluation To be Published
|
|
2QN2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qn2 by Molmil](/molmil-images/mine/2qn2) | Glycogen Phosphorylase b in complex with Maslinic Acid | 分子名称: | Glycogen phosphorylase, muscle form, maslinic acid | 著者 | Zographos, S.E, Leonidas, D.D, Alexacou, K.-M, Hayes, J, Oikonomakos, N.G. | 登録日 | 2007-07-17 | 公開日 | 2008-06-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.698 Å) | 主引用文献 | Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies J.Med.Chem., 51, 2008
|
|
2QN8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qn8 by Molmil](/molmil-images/mine/2qn8) | Glycogen Phosphorylase b in complex with N-4-nitrobenzoyl-N'-beta-D-glucopyranosyl urea | 分子名称: | Glycogen phosphorylase, muscle form, N-{[(4-nitrophenyl)carbonyl]carbamoyl}-beta-D-glucopyranosylamine, ... | 著者 | Chrysina, E.D, Tiraidis, C, Alexacou, K.-M, Zographos, S.E, Leonidas, D.D, Oikonomakos, N.G. | 登録日 | 2007-07-18 | 公開日 | 2008-07-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | N-(4-substituted-benzoyl)-N'-(beta-D-glucopyranosyl)ureas, inhibitors of glycogen phosphorylase: synthesis, kinetic and crystallographic evaluation To be Published
|
|
2QRH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qrh by Molmil](/molmil-images/mine/2qrh) | Glycogen Phosphorylase b in complex with (1R)-3'-phenylspiro[1,5-anhydro-D-glucitol-1,5'-isoxazoline] | 分子名称: | (5R,7R,8S,9S,10R)-7-(hydroxymethyl)-3-phenyl-1,6-dioxa-2-azaspiro[4.5]dec-2-ene-8,9,10-triol, Glycogen phosphorylase, muscle form | 著者 | Kizilis, G, Alexacou, K.-M, Chrysina, E.D, Zographos, S.E, Leonidas, D.D, Oikonomakos, N.G. | 登録日 | 2007-07-28 | 公開日 | 2008-08-05 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Glucose-based spiro-isoxazolines: a new family of potent glycogen phosphorylase inhibitors. Bioorg.Med.Chem., 17, 2009
|
|
2QRG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qrg by Molmil](/molmil-images/mine/2qrg) | Glycogen Phosphorylase b in complex with (1R)-3'-(4-methoxyphenyl)-spiro[1,5-anhydro-D-glucitol-1,5'-isoxazoline] | 分子名称: | (5R,7R,8S,9S,10R)-7-(HYDROXYMETHYL)-3-(4-METHOXYPHENYL)-1,6-DIOXA-2-AZASPIRO[4.5]DEC-2-ENE-8,9,10-TRIOL, Glycogen phosphorylase, muscle form | 著者 | Kizilis, G, Alexacou, K.-M, Chrysina, E.D, Zographos, S.E, Leonidas, D.D, Oikonomakos, N.G. | 登録日 | 2007-07-28 | 公開日 | 2008-08-05 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Glucose-based spiro-isoxazolines: a new family of potent glycogen phosphorylase inhibitors. Bioorg.Med.Chem., 17, 2009
|
|
3EBO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ebo by Molmil](/molmil-images/mine/3ebo) | Glycogen Phosphorylase b/Chrysin complex | 分子名称: | Glycogen phosphorylase, muscle form, chrysin | 著者 | Oikonomakos, N.G, Zographos, S.E, Leonidas, D.D, Hayes, J.M, Tiraidis, C, Alexacou, K.-M. | 登録日 | 2008-08-28 | 公開日 | 2009-09-01 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Sourcing the affinity of flavonoids for the glycogen phosphorylase inhibitor site via crystallography, kinetics and QM/MM-PBSA binding studies: Comparison of chrysin and flavopiridol Food Chem.Toxicol., 61, 2013
|
|
3EBP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ebp by Molmil](/molmil-images/mine/3ebp) | Glycogen Phosphorylase b/flavopiridol complex | 分子名称: | 2-(2-CHLORO-PHENYL)-5,7-DIHYDROXY-8-(3-HYDROXY-1-METHYL-PIPERIDIN-4-YL)-4H-BENZOPYRAN-4-ONE, Glycogen phosphorylase, muscle form | 著者 | Oikonomakos, N.G, Zographos, S.E, Leonidas, D.D, Hayes, J.M, Tiraidis, C, Alexacou, K.-M. | 登録日 | 2008-08-28 | 公開日 | 2009-09-01 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Sourcing the affinity of flavonoids for the glycogen phosphorylase inhibitor site via crystallography, kinetics and QM/MM-PBSA binding studies: Comparison of chrysin and flavopiridol Food Chem.Toxicol., 61, 2013
|
|