2QN3

Glycogen Phosphorylase in complex with N-4-chlorobenzoyl-N-beta-D-glucopyranosyl urea

Summary for 2QN3

• Entry DOI: 10.2210/pdb2qn3/pdb
• Related: 2QLM 2QLN 2QN7 2QN8 2QN9 2QNB
• Descriptor: Glycogen phosphorylase, muscle form, N-{[(4-chlorophenyl)carbonyl]carbamoyl}-beta-D-glucopyranosylamine (3 entities in total)
• Functional Keywords: glycogenolysis, type 2 diabetes, acetylation, allosteric enzyme, carbohydrate metabolism, glycogen metabolism, glycosyltransferase, nucleotide-binding, phosphoprotein, pyridoxal phosphate, transferase
• Biological source: Oryctolagus cuniculus (Rabbit)
• Total number of polymer chains: 1
• Total formula weight: 97880.07

Authors

Chrysina, E.D.,Tiraidis, C.,Alexacou, K.-M.,Zographos, S.E.,Leonidas, D.D.,Oikonomakos, N.G. (deposition date: 2007-07-17, release date: 2008-07-22, Last modification date: 2023-11-15)

• Primary citation: Nagy, V.,Felf ldi, N.,Praly, J.-P.,Dosca, T.,Gergerly, P.,Chrysina, E.D.,Tiraidis, C.,Kosmopoulou, M.N.,Alexacou, K.-M.,Konstantakaki, M.; N-(4-substituted-benzoyl)-N'-(beta-D-glucopyranosyl)ureas, inhibitors of glycogen phosphorylase: synthesis, kinetic and crystallographic evaluation; To be Published,

Experimental method

X-RAY DIFFRACTION (1.96 Å)