3G6V
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5ULP
| Structure of the NS5 methyltransferase from Zika bound to MS2042 | Descriptor: | 5'-{[(3S)-3-amino-3-carboxypropyl][(4-fluorophenyl)methyl]amino}-5'-deoxyadenosine, CHLORIDE ION, ISOPROPYL ALCOHOL, ... | Authors: | Jain, R, Aggarwal, A.K. | Deposit date: | 2017-01-25 | Release date: | 2017-05-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Development of a S-adenosylmethionine analog that intrudes the RNA-cap binding site of Zika methyltransferase. Sci Rep, 7, 2017
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3IAY
| Ternary complex of DNA polymerase delta | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', 5'-D(*TP*AP*AP*GP*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*AP*T)-3', ... | Authors: | Swan, M.K, Aggarwal, A.K. | Deposit date: | 2009-07-15 | Release date: | 2009-09-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta Nat.Struct.Mol.Biol., 16, 2009
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4EEY
| Crystal structure of human DNA polymerase eta in ternary complex with a cisplatin DNA adduct | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*TP*TP*GP*GP*TP*CP*TP*CP*CP*TP*CP*C)-3', 5'-D(*TP*GP*GP*AP*GP*GP*AP*GP*A)-3', ... | Authors: | Ummat, A, Rechkoblit, O, Jain, R, Choudhury, J.R, Johnson, R.E, Silverstein, T.D, Buku, A, Lone, S, Prakash, L, Prakash, S, Aggarwal, A.K. | Deposit date: | 2012-03-28 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Structural basis for cisplatin DNA damage tolerance by human polymerase {eta} during cancer chemotherapy. Nat.Struct.Mol.Biol., 19, 2012
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5WMB
| Structure of the 10S (-)-cis-BP-dG modified Rev1 ternary complex (the BP residue is disordered) | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Rechkoblit, O, Kolbanovsky, A, Landes, H, Geacintov, N.E, Aggarwal, A.K. | Deposit date: | 2017-07-28 | Release date: | 2017-10-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase. Nat Commun, 8, 2017
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3QU3
| Crystal structure of IRF-7 DBD apo form | Descriptor: | 1,2-ETHANEDIOL, Interferon regulatory factor 7, SODIUM ION | Authors: | De Ioannes, P.E, Escalante, C.R, Aggarwal, A.K. | Deposit date: | 2011-02-23 | Release date: | 2011-06-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structures of apo IRF-3 and IRF-7 DNA binding domains: effect of loop L1 on DNA binding. Nucleic Acids Res., 39, 2011
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3OHA
| Yeast DNA polymerase eta inserting dCTP opposite an 8oxoG lesion | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*TP*CP*CP*TP*CP*CP*CP*CP*TP*(DOC))-3', 5'-D(P*TP*(8OG)P*GP*AP*GP*GP*GP*GP*AP*GP*GP*AP*C)-3', ... | Authors: | Silverstein, T.D, Jain, R, Aggarwal, A.K. | Deposit date: | 2010-08-17 | Release date: | 2010-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase eta. Structure, 18, 2010
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3QU6
| Crystal structure of IRF-3 DBD free form | Descriptor: | CHLORIDE ION, IRF3 protein, SODIUM ION, ... | Authors: | De Ioannes, P.E, Escalante, C.R, Aggarwal, A.K. | Deposit date: | 2011-02-23 | Release date: | 2011-06-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of apo IRF-3 and IRF-7 DNA binding domains: effect of loop L1 on DNA binding. Nucleic Acids Res., 39, 2011
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3OSP
| Structure of rev1 | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', 5'-D(*TP*AP*AP*(3DR)P*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*AP*T)-3', ... | Authors: | Nair, D.T, Aggarwal, A.K. | Deposit date: | 2010-09-09 | Release date: | 2011-04-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | DNA synthesis across an abasic lesion by yeast REV1 DNA polymerase. J.Mol.Biol., 406, 2011
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3PZP
| Human DNA polymerase kappa extending opposite a cis-syn thymine dimer | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*CP*A)-3', 5'-D(*TP*TP*CP*CP*(TTD)P*GP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', ... | Authors: | Vasquez-Del Carpio, R, Silverstein, T.D, Lone, S, Johnson, R.E, Prakash, S, Prakash, L, Aggarwal, A.K. | Deposit date: | 2010-12-14 | Release date: | 2011-12-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.336 Å) | Cite: | Role of human DNA polymerase kappa in extension opposite from a cis-syn thymine dimer. J.Mol.Biol., 408, 2011
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3ODH
| Structure of OkrAI/DNA complex | Descriptor: | CALCIUM ION, DNA (5'-D(*TP*AP*TP*GP*GP*AP*TP*CP*CP*AP*TP*A)-3'), OkrAI endonuclease | Authors: | Vanamee, E.S, Aggarwal, A.K. | Deposit date: | 2010-08-11 | Release date: | 2010-10-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Asymmetric DNA recognition by the OkrAI endonuclease, an isoschizomer of BamHI. Nucleic Acids Res., 39, 2011
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