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PDB: 108 件
1G6X
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ULTRA HIGH RESOLUTION STRUCTURE OF BOVINE PANCREATIC TRYPSIN INHIBITOR (BPTI) MUTANT WITH ALTERED BINDING LOOP SEQUENCE
分子名称: 1,2-ETHANEDIOL, PANCREATIC TRYPSIN INHIBITOR, SULFATE ION
著者Addlagatta, A, Czapinska, H, Krzywda, S, Otlewski, J, Jaskolski, M.
登録日2000-11-08
公開日2001-05-09
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (0.86 Å)
主引用文献Ultrahigh-resolution structure of a BPTI mutant.
Acta Crystallogr.,Sect.D, 57, 2001
3CSX
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Structural characterization of a protein in the DUF683 family- crystal structure of cce_0567 from the cyanobacterium Cyanothece 51142.
分子名称: NICKEL (II) ION, Putative uncharacterized protein
著者Addlagatta, A, Robinson, H, Buchko, G.W.
登録日2008-04-10
公開日2008-06-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structural characterization of the protein cce_0567 from Cyanothece 51142, a metalloprotein associated with nitrogen fixation in the DUF683 family.
Biochim.Biophys.Acta, 1794, 2009
3KED
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Crystal structure of Aminopeptidase N in complex with 2,4-diaminobutyric acid
分子名称: 2,4-DIAMINOBUTYRIC ACID, Aminopeptidase N, GLYCEROL, ...
著者Addlagatta, A, Gumpena, R.
登録日2009-10-25
公開日2010-11-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of alpha, beta- and alpha, gamma-Diamino Acid Scaffolds for the Inhibition of M1 Family Aminopeptidases
Chemmedchem, 6, 2011
2B3H
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Crystal structure of Human Methionine Aminopeptidase Type I with a third cobalt in the active site
分子名称: CHLORIDE ION, COBALT (II) ION, GLYCEROL, ...
著者Addlagatta, A, Hu, X, Liu, J.O, Matthews, B.W.
登録日2005-09-20
公開日2005-11-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Structural Basis for the Functional Differences between Type I and Type II Human Methionine Aminopeptidases(,).
Biochemistry, 44, 2005
2G6P
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Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with Pyridyl pyrimidine derivative
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-CHLORO-6-METHYL-N-(2-PHENYLETHYL)-2-PYRIDIN-2-YLPYRIMIDIN-4-AMINE, COBALT (II) ION, ...
著者Addlagatta, A, Hu, X, Liu, J.O, Matthews, B.W.
登録日2006-02-24
公開日2006-06-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Identification of Pyridinylpyrimidines as Inhibitors of Human Methionine Aminopeptidases.
Angew.Chem.Int.Ed.Engl., 45, 2006
2GZ5
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Human Type 1 methionine aminopeptidase in complex with ovalicin at 1.1 Ang
分子名称: 3,4-DIHYDROXY-2-METHOXY-4-METHYL-3-[2-METHYL-3-(3-METHYL-BUT-2-ENYL) -OXIRANYL]-CYCLOHEXANONE, COBALT (II) ION, GLYCEROL, ...
著者Addlagatta, A, Matthews, B.W.
登録日2006-05-10
公開日2006-05-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Structure of the angiogenesis inhibitor ovalicin bound to its noncognate target, human Type 1 methionine aminopeptidase.
Protein Sci., 15, 2006
2HPT
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Crystal Structure of E. coli PepN (Aminopeptidase N)in complex with Bestatin
分子名称: 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, Aminopeptidase N, GLYCEROL, ...
著者Addlagatta, A, Matthews, B.W, Gay, L.
登録日2006-07-17
公開日2006-08-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of aminopeptidase N from Escherichia coli suggests a compartmentalized, gated active site.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HPO
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Structure of Aminopeptidase N from E. coli Suggests a Compartmentalized, Gated Active Site
分子名称: Aminopeptidase N, GLYCEROL, ZINC ION
著者Addlagatta, A, Matthews, B.W, Gay, L.
登録日2006-07-17
公開日2006-08-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of aminopeptidase N from Escherichia coli suggests a compartmentalized, gated active site.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3PUU
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Crystal Structure of Glu121Gln mutant of E. coli Aminopeptidase N
分子名称: Aminopeptidase N, GLYCEROL, SULFATE ION, ...
著者Addlagatta, A.
登録日2010-12-06
公開日2011-11-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Discovery of alpha, beta- and alpha, gamma-Diamino Acid Scaffolds for the Inhibition of M1 Family Aminopeptidases
Chemmedchem, 6, 2011
6LVH
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Crystal structure of methionine aminopeptidase from Pyrococcus furiosus
分子名称: GLYCEROL, Methionine aminopeptidase
著者Addlagatta, A, Sandeep, C.B.
登録日2020-02-03
公開日2021-02-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of methionine aminopeptidase from Pyrococcus furiosus
To Be Published
3QJX
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Crystal Structure of E. coli Aminopeptidase N in complex with L-Serine
分子名称: Aminopeptidase N, GLYCEROL, MALONATE ION, ...
著者Addlagatta, A, Gumpena, R, Kishor, C, Ganji, R.J.
登録日2011-01-31
公開日2011-11-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Discovery of alpha, beta- and alpha, gamma-Diamino Acid Scaffolds for the Inhibition of M1 Family Aminopeptidases
Chemmedchem, 6, 2011
3B2X
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Crystal Structure of E. coli Aminopeptidase N in complex with Lysine
分子名称: Aminopeptidase N, GLYCEROL, LYSINE, ...
著者Addlagatta, A, Gay, L, Matthews, B.W.
登録日2007-10-19
公開日2008-05-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis for the unusual specificity of Escherichia coli aminopeptidase N.
Biochemistry, 47, 2008
1Y1N
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Identification of SH3 motif in M. Tuberculosis methionine aminopeptidase suggests a mode of interaction with the ribosome
分子名称: Methionine aminopeptidase 1B, POTASSIUM ION
著者Addlagatta, A, Quillin, M.L, Omotoso, O, Liu, J.O, Matthews, B.W.
登録日2004-11-18
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Identification of an SH3-Binding Motif in a New Class of Methionine Aminopeptidases from Mycobacterium tuberculosis Suggests a Mode of Interaction with the Ribosome
Biochemistry, 44, 2005
1YJ3
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Crystal structure analysis of product bound methionine aminopeptidase Type 1c from Mycobacterium Tuberculosis
分子名称: BETA-MERCAPTOETHANOL, COBALT (II) ION, METHIONINE, ...
著者Addlagatta, A, Quillin, M.L, Omotoso, O, Liu, J.O, Matthews, B.W.
登録日2005-01-13
公開日2005-07-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Identification of an SH3-binding motif in a new class of methionine aminopeptidases from Mycobacterium tuberculosis suggests a mode of interaction with the ribosome.
Biochemistry, 44, 2005
2B3K
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Crystal structure of Human Methionine Aminopeptidase Type I in the holo form
分子名称: ACETATE ION, COBALT (II) ION, GLYCEROL, ...
著者Addlagatta, A, Hu, X, Liu, J.O, Matthews, B.W.
登録日2005-09-20
公開日2005-11-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural Basis for the Functional Differences between Type I and Type II Human Methionine Aminopeptidases(,).
Biochemistry, 44, 2005
2B3L
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Crystal structure of type I human methionine aminopeptidase in the apo form
分子名称: ACETIC ACID, GLYCEROL, Methionine aminopeptidase 1, ...
著者Addlagatta, A, Hu, X, Liu, J.O, Matthews, B.W.
登録日2005-09-20
公開日2005-11-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Basis for the Functional Differences between Type I and Type II Human Methionine Aminopeptidases(,).
Biochemistry, 44, 2005
2NQ6
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Crystal structure of human methionine aminopeptidase type 1 in complex with 3-tert-Butoxycarbonylaminopyridine-2-carboxylic acid thiazole-2-ylamide
分子名称: CALCIUM ION, COBALT (II) ION, GLYCEROL, ...
著者Addlagatta, A, Matthews, B.W.
登録日2006-10-30
公開日2006-11-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Elucidation of the function of type 1 human methionine aminopeptidase during cell cycle progression.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2NQ7
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Crystal structure of type 1 human methionine aminopeptidase in complex with 3-(2,2-Dimethylpropionylamino)pyridine-2-carboxylic acid thiazole-2-ylamide
分子名称: 3-[(2,2-DIMETHYLPROPANOYL)AMINO]-N-1,3-THIAZOL-2-YLPYRIDINE-2-CARBOXAMIDE, COBALT (II) ION, GLYCEROL, ...
著者Addlagatta, A, Matthews, B.W.
登録日2006-10-30
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Elucidation of the function of type 1 human methionine aminopeptidase during cell cycle progression.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3B3B
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Crystal structure of E. coli Aminopeptidase N in complex with tryptophan
分子名称: Aminopeptidase N, GLYCEROL, MALONATE ION, ...
著者Addlagatta, A.
登録日2007-10-19
公開日2008-05-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis for the unusual specificity of Escherichia coli aminopeptidase N.
Biochemistry, 47, 2008
3B37
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Crystal structure of E. coli Aminopeptidase N in complex with Tyrosine
分子名称: Aminopeptidase N, GLYCEROL, MALONATE ION, ...
著者Addlagatta, A.
登録日2007-10-19
公開日2008-05-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for the unusual specificity of Escherichia coli aminopeptidase N.
Biochemistry, 47, 2008
3B34
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Crystal structure of E. coli Aminopeptidase N in complex with Phenylalanine
分子名称: Aminopeptidase N, GLYCEROL, MALONATE ION, ...
著者Addlagatta, A.
登録日2007-10-19
公開日2008-05-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural basis for the unusual specificity of Escherichia coli aminopeptidase N.
Biochemistry, 47, 2008
4IKT
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Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with N1-(5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)-N2-(5-(trifluoromethyl)pyridin-2-yl)ethane-1,2-diamine
分子名称: COBALT (II) ION, GLYCEROL, Methionine aminopeptidase 1, ...
著者Addlagatta, A, Kishor, C, Arya, T.
登録日2012-12-28
公開日2013-12-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Identification, Biochemical and Structural Evaluation of Species-Specific Inhibitors against Type I Methionine Aminopeptidases
J.Med.Chem., 56, 2013
4IKS
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Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with N1-(5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)-N2-(6-(trifluoromethyl)pyridin-2-yl)ethane-1,2-diamine
分子名称: COBALT (II) ION, GLYCEROL, Methionine aminopeptidase 1, ...
著者Addlagatta, A, Kishor, C, Arya, T.
登録日2012-12-28
公開日2013-12-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Identification, Biochemical and Structural Evaluation of Species-Specific Inhibitors against Type I Methionine Aminopeptidases
J.Med.Chem., 56, 2013
4IKR
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Crystal structure of Type 1 human methionine aminopeptidase in complex with 2-(4-(5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)piperazin-1-yl)ethanol
分子名称: 2-{4-[5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl]piperazin-1-yl}ethanol, COBALT (II) ION, GLYCEROL, ...
著者Addlagatta, A, Kishor, C, Arya, T.
登録日2012-12-28
公開日2013-12-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Identification, Biochemical and Structural Evaluation of Species-Specific Inhibitors against Type I Methionine Aminopeptidases
J.Med.Chem., 56, 2013
4IKU
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Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with 2-((5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)amino)-3-phenylpropanamide
分子名称: COBALT (II) ION, Methionine aminopeptidase 1, Nalpha-[5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl]-D-phenylalaninamide, ...
著者Addlagatta, A, Kishor, C, Arya, T.
登録日2012-12-28
公開日2013-12-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Identification, Biochemical and Structural Evaluation of Species-Specific Inhibitors against Type I Methionine Aminopeptidases
J.Med.Chem., 56, 2013

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