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3KED

Crystal structure of Aminopeptidase N in complex with 2,4-diaminobutyric acid

Summary for 3KED
Entry DOI10.2210/pdb3ked/pdb
Related2hpo
DescriptorAminopeptidase N, ZINC ION, 2,4-DIAMINOBUTYRIC ACID, ... (7 entities in total)
Functional Keywordsaminopeptidase, thermolysin like active site, amino switch, inhibitor, ligand design, cell inner membrane, cell membrane, hydrolase, membrane, metal-binding, metalloprotease, protease
Biological sourceEscherichia coli
Cellular locationCell inner membrane; Peripheral membrane protein; Cytoplasmic side: P04825
Total number of polymer chains1
Total formula weight102811.75
Authors
Addlagatta, A.,Gumpena, R. (deposition date: 2009-10-25, release date: 2010-11-03, Last modification date: 2023-11-01)
Primary citationGumpena, R.,Kishor, C.,Ganji, R.J.,Addlagatta, A.
Discovery of alpha, beta- and alpha, gamma-Diamino Acid Scaffolds for the Inhibition of M1 Family Aminopeptidases
Chemmedchem, 6:1971-1976, 2011
Cited by
PubMed: 22025387
DOI: 10.1002/cmdc.201100298
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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