4E22
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4BZR
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![BU of 4bzr by Molmil](/molmil-images/mine/4bzr) | Human testis angiotensin converting enzyme in complex with K-26 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ACETATE ION, ... | Authors: | Kramer, G.J, Mohd, A, Schwager, S.L.U, Masuyer, G, Acharya, K.R, Sturrock, E.D, Bachmann, B.O. | Deposit date: | 2013-07-29 | Release date: | 2014-02-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Interkingdom Pharmacology of Angiotensin-I Converting Enzyme Inhibitor Phosphonates Produced by Actinomycetes Acs Med.Chem.Lett., 5, 2014
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4C2N
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![BU of 4c2n by Molmil](/molmil-images/mine/4c2n) | Crystal structure of human testis angiotensin-I converting enzyme mutant E403R | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ANGIOTENSIN-CONVERTING ENZYME, CHLORIDE ION, ... | Authors: | Masuyer, G, Yates, C.J, Schwager, S.L.U, Mohd, A, Sturrock, E.D, Acharya, K.R. | Deposit date: | 2013-08-19 | Release date: | 2013-12-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Molecular and Thermodynamic Mechanisms of the Chloride Dependent Human Angiotensin-I Converting Enzyme (Ace) J.Biol.Chem., 289, 2014
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4C2O
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![BU of 4c2o by Molmil](/molmil-images/mine/4c2o) | Crystal structure of human testis angiotensin-I converting enzyme mutant D465T | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ACETATE ION, ... | Authors: | Masuyer, G, Yates, C.J, Schwager, S.L.U, Mohd, A, Sturrock, E.D, Acharya, K.R. | Deposit date: | 2013-08-19 | Release date: | 2013-12-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular and Thermodynamic Mechanisms of the Chloride Dependent Human Angiotensin-I Converting Enzyme (Ace) J.Biol.Chem., 289, 2014
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4CA5
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![BU of 4ca5 by Molmil](/molmil-images/mine/4ca5) | Human Angiotensin converting enzyme in complex with a phosphinic tripeptide FI | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | Authors: | Masuyer, G, Akif, M, Czarny, B, Beau, F, Schwager, S.L.U, Sturrock, E.D, Isaac, R.E, Dive, V, Acharya, K.R. | Deposit date: | 2013-10-07 | Release date: | 2013-12-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal Structures of Highly Specific Phosphinic Tripeptide Enantiomers in Complex with the Angiotensin-I Converting Enzyme. FEBS J., 281, 2014
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4BZS
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![BU of 4bzs by Molmil](/molmil-images/mine/4bzs) | Human angiotenisn converting enzyme N-domain in complex with K-26 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ANGIOTENSIN-CONVERTING ENZYME, ... | Authors: | Kramer, G.J, Mohd, A, Schwager, S.L.U, Masuyer, G, Acharya, K.R, Sturrock, E.D, Bachmann, B.O. | Deposit date: | 2013-07-29 | Release date: | 2014-02-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Interkingdom Pharmacology of Angiotensin-I Converting Enzyme Inhibitor Phosphonates Produced by Actinomycetes Acs Med.Chem.Lett., 5, 2014
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4CA6
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![BU of 4ca6 by Molmil](/molmil-images/mine/4ca6) | Human Angiotensin converting enzyme N-domain in complex with a phosphinic tripeptide FI | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME N-DOMAIN, CHLORIDE ION, ... | Authors: | Masuyer, G, Akif, M, Czarny, B, Beau, F, Schwager, S.L.U, Sturrock, E.D, Isaac, R.E, Dive, V, Acharya, K.R. | Deposit date: | 2013-10-07 | Release date: | 2013-12-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin-I converting enzyme. FEBS J., 281, 2014
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4BXK
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![BU of 4bxk by Molmil](/molmil-images/mine/4bxk) | Crystal structure of the Angiotensin-1 converting enzyme N-domain in complex with a domain-specific inhibitor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME, ... | Authors: | Douglas, R.G, Sharma, R.K, Masuyer, G, Lubbe, L, Zamora, I, Acharya, K.R, Chibale, K, Sturrock, E.D. | Deposit date: | 2013-07-12 | Release date: | 2013-09-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Fragment-Based Design for the Development of N-Domain Selective Angiotensin-1 Converting Enzyme Inhibitors Clin.Sci., 126, 2014
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4C2P
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![BU of 4c2p by Molmil](/molmil-images/mine/4c2p) | Crystal structure of human testis angiotensin-I converting enzyme mutant R522K in complex with captopril | Descriptor: | ACETATE ION, ANGIOTENSIN-CONVERTING ENZYME, CHLORIDE ION, ... | Authors: | Masuyer, G, Yates, C.J, Schwager, S.L.U, Mohd, A, Sturrock, E.D, Acharya, K.R. | Deposit date: | 2013-08-19 | Release date: | 2013-12-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Molecular and Thermodynamic Mechanisms of the Chloride Dependent Human Angiotensin-I Converting Enzyme (Ace) J.Biol.Chem., 289, 2014
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4CA7
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![BU of 4ca7 by Molmil](/molmil-images/mine/4ca7) | Drosophila Angiotensin converting enzyme (AnCE) in complex with a phosphinic tripeptide FI | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME, N-{(2S)-3-[(S)-[(1R)-1-{[(benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]-2-[(3-phenyl-1,2-oxazol-5-yl)methyl]propanoyl}-L-tyrosine, ... | Authors: | Masuyer, G, Akif, M, Czarny, B, Beau, F, Schwager, S.L.U, Sturrock, E.D, Isaac, R.E, Dive, V, Acharya, K.R. | Deposit date: | 2013-10-07 | Release date: | 2013-12-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Crystal Structures of Highly Specific Phosphinic Tripeptide Enantiomers in Complex with the Angiotensin-I Converting Enzyme. FEBS J., 281, 2014
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4C2Q
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![BU of 4c2q by Molmil](/molmil-images/mine/4c2q) | Crystal structure of human testis angiotensin-I converting enzyme mutant R522K | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ACETATE ION, ANGIOTENSIN-CONVERTING ENZYME, ... | Authors: | Masuyer, G, Yates, C.J, Schwager, S.L.U, Mohd, A, Sturrock, E.D, Acharya, K.R. | Deposit date: | 2013-08-19 | Release date: | 2013-12-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular and Thermodynamic Mechanisms of the Chloride Dependent Human Angiotensin-I Converting Enzyme (Ace) J.Biol.Chem., 289, 2014
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4CA8
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![BU of 4ca8 by Molmil](/molmil-images/mine/4ca8) | Drosophila Angiotensin converting enzyme (AnCE) in complex with a phosphinic tripeptide FII | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME, SULFATE ION, ... | Authors: | Masuyer, G, Akif, M, Czarny, B, Beau, F, Schwager, S.L.U, Sturrock, E.D, Isaac, R.E, Dive, V, Acharya, K.R. | Deposit date: | 2013-10-07 | Release date: | 2013-12-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Crystal Structures of Highly Specific Phosphinic Tripeptide Enantiomers in Complex with the Angiotensin-I Converting Enzyme. FEBS J., 281, 2014
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4B36
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![BU of 4b36 by Molmil](/molmil-images/mine/4b36) | |
4CJC
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![BU of 4cjc by Molmil](/molmil-images/mine/4cjc) | orthorhombic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP, GalNAc | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, GLYCOSYLTRANSFERASE FAMILY 6, URIDINE-5'-DIPHOSPHATE, ... | Authors: | Pham, T, Stinson, B, Thiyagarajan, N, Lizotte-Waniewski, M, Brew, K, Acharya, K.R. | Deposit date: | 2013-12-19 | Release date: | 2014-02-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.42 Å) | Cite: | Structures of Complexes of a Metal-Independent Glycosyltransferase Gt6 from Bacteroides Ovatus with Udp-Galnac and its Hydrolysis Products. J.Biol.Chem., 289, 2014
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4CI7
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![BU of 4ci7 by Molmil](/molmil-images/mine/4ci7) | The crystal structure of the cysteine protease and lectin-like domains of Cwp84, a surface layer associated protein of Clostridium difficile | Descriptor: | CALCIUM ION, CELL SURFACE PROTEIN (PUTATIVE CELL SURFACE-ASSOCIATED CYSTEINE PROTEASE), GLYCEROL, ... | Authors: | Bradshaw, W.J, Kirby, J.M, Thiyagarajan, N, Chambers, C.J, Davies, A.H, Roberts, A.K, Shone, C.C, Acharya, K.R. | Deposit date: | 2013-12-06 | Release date: | 2014-05-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The Structure of the Cysteine Protease and Lectin-Like Domains of Cwp84, a Surface Layer-Associated Protein from Clostridium Difficile Acta Crystallogr.,Sect.D, 70, 2014
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4C2R
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![BU of 4c2r by Molmil](/molmil-images/mine/4c2r) | Crystal structure of human testis angiotensin-I converting enzyme mutant R522Q | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ACETATE ION, ANGIOTENSIN-CONVERTING ENZYME, ... | Authors: | Masuyer, G, Yates, C.J, Schwager, S.L.U, Mohd, A, Sturrock, E.D, Acharya, K.R. | Deposit date: | 2013-08-19 | Release date: | 2013-12-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Molecular and Thermodynamic Mechanisms of the Chloride Dependent Human Angiotensin-I Converting Enzyme (Ace) J.Biol.Chem., 289, 2014
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4D5A
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![BU of 4d5a by Molmil](/molmil-images/mine/4d5a) | Clostridial Cysteine protease Cwp84 C116A after propeptide cleavage | Descriptor: | CALCIUM ION, CELL SURFACE PROTEIN (PUTATIVE CELL SURFACE-ASSOCIATED CYSTEINE PROTEASE), GLYCEROL, ... | Authors: | Bradshaw, W.J, Roberts, A.K, Shone, C.C, Acharya, K.R. | Deposit date: | 2014-11-03 | Release date: | 2015-03-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Cwp84, a Clostridium Difficile Cysteine Protease, Exhibits Conformational Flexibility in the Absence of its Propeptide Acta Crystallogr.,Sect.F, 71, 2015
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4D59
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![BU of 4d59 by Molmil](/molmil-images/mine/4d59) | Clostridial Cysteine protease Cwp84 C116A after propeptide cleavage | Descriptor: | CALCIUM ION, CELL SURFACE PROTEIN (PUTATIVE CELL SURFACE-ASSOCIATED CYSTEINE PROTEASE), O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500) | Authors: | Bradshaw, W.J, Roberts, A.K, Shone, C.C, Acharya, K.R. | Deposit date: | 2014-11-03 | Release date: | 2015-03-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Cwp84, a Clostridium Difficile Cysteine Protease, Exhibits Conformational Flexibility in the Absence of its Propeptide Acta Crystallogr.,Sect.F, 71, 2015
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3ZUQ
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![BU of 3zuq by Molmil](/molmil-images/mine/3zuq) | Crystal structure of an engineered botulinum neurotoxin type B - derivative, LC-B-GS-Hn-B | Descriptor: | BOTULINUM NEUROTOXIN TYPE B, ZINC ION | Authors: | Masuyer, G, Stancombe, P, Chaddock, J.A, Acharya, K.R. | Deposit date: | 2011-07-19 | Release date: | 2011-12-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structures of Engineered Clostridium Botulinum Neurotoxin Derivatives Acta Crystallogr.,Sect.F, 67, 2011
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3ZXF
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![BU of 3zxf by Molmil](/molmil-images/mine/3zxf) | High resolution structure of Human Galectin-7 | Descriptor: | ACETATE ION, GALECTIN-7 | Authors: | Masuyer, G, Oberg, C.T, Leffler, H, Nilsson, U.J, Acharya, K.R. | Deposit date: | 2011-08-10 | Release date: | 2011-11-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Inhibition Mechanism of Human Galectin-7 by a Novel Galactose-Benzylphosphate Inhibitor. FEBS J., 279, 2012
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3ZXE
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![BU of 3zxe by Molmil](/molmil-images/mine/3zxe) | Crystal structure of Human Galectin-7 in complex with a galactose- benzylphosphate inhibitor | Descriptor: | GALECTIN-7, METHYL 2-O-[(S)-(BENZYLOXY)(HYDROXY)PHOSPHORYL]-3-DEOXY-3-{[(4-METHYLPHENYL)CARBONYL]AMINO}-1-THIO-BETA-D-GALACTOPYRANOSIDE | Authors: | Masuyer, G, Oberg, C.T, Leffler, H, Nilsson, U.J, Acharya, K.R. | Deposit date: | 2011-08-10 | Release date: | 2011-11-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Inhibition Mechanism of Human Galectin-7 by a Novel Galactose-Benzylphosphate Inhibitor. FEBS J., 279, 2012
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3ZBV
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![BU of 3zbv by Molmil](/molmil-images/mine/3zbv) | Crystal Structure of murine Angiogenin-2 | Descriptor: | ANGIOGENIN-2, GLYCEROL, SULFATE ION, ... | Authors: | Iyer, S, Holloway, D.E, Acharya, K.R. | Deposit date: | 2012-11-13 | Release date: | 2012-12-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Crystal Structures of Murine Angiogenin-2 and -3 - Probing 'Structure - Function' Relationships Amongst Angiogenin Homologues. FEBS J., 280, 2013
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3ZUR
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![BU of 3zur by Molmil](/molmil-images/mine/3zur) | Crystal structure of an engineered botulinum neurotoxin type A- SNARE23 derivative, LC0-A-SNAP25-Hn-A | Descriptor: | BOTULINUM NEUROTOXIN TYPE A, SYNAPTOSOMAL-ASSOCIATED PROTEIN, SULFATE ION | Authors: | Masuyer, G, Stancombe, P, Chaddock, J.A, Acharya, K.R. | Deposit date: | 2011-07-19 | Release date: | 2011-12-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Structures of Engineered Clostridium Botulinum Neurotoxin Derivatives Acta Crystallogr.,Sect.F, 67, 2011
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4AHL
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![BU of 4ahl by Molmil](/molmil-images/mine/4ahl) | P112L - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | Descriptor: | ANGIOGENIN, L(+)-TARTARIC ACID | Authors: | Thiyagarajan, N, Ferguson, R, Saha, S, Pham, T, Subramanian, V, Acharya, K.R. | Deposit date: | 2012-02-06 | Release date: | 2012-10-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.053 Å) | Cite: | Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons. Nat.Commun., 3, 2012
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4APJ
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![BU of 4apj by Molmil](/molmil-images/mine/4apj) | Human angiotensin-converting enzyme in complex with BPPb | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ACETATE ION, ANGIOTENSIN-CONVERTING ENZYME, ... | Authors: | Masuyer, G, Schwager, S.L.U, Sturrock, E.D, Isaac, R.E, Acharya, K.R. | Deposit date: | 2012-04-03 | Release date: | 2012-10-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular Recognition and Regulation of Human Angiotensin-I Converting Enzyme (Ace) Activity by Natural Inhibitory Peptides. Sci.Rep., 2, 2012
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