4BZS

Human angiotenisn converting enzyme N-domain in complex with K-26

Summary for 4BZS

• Entry DOI: 10.2210/pdb4bzs/pdb
• Related: 4BZR
• Descriptor: ANGIOTENSIN-CONVERTING ENZYME, N-ACETYL-L-ILE-L-TYR-(R)-1-AMINO-2-(4-HYDROXYPHENYL)ETHYLPHOSPHONIC ACID, thiodiglycolic acid, ... (13 entities in total)
• Functional Keywords: hydrolase, zinc metallopeptidase, antihypertensive agent
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 2
• Total formula weight: 150571.69

Authors

Kramer, G.J.,Mohd, A.,Schwager, S.L.U.,Masuyer, G.,Acharya, K.R.,Sturrock, E.D.,Bachmann, B.O. (deposition date: 2013-07-29, release date: 2014-02-26, Last modification date: 2023-12-20)

• Primary citation: Kramer, G.J.,Mohd, A.,Schwager, S.L.U.,Masuyer, G.,Acharya, K.R.,Sturrock, E.D.,Bachmann, B.O.; Interkingdom Pharmacology of Angiotensin-I Converting Enzyme Inhibitor Phosphonates Produced by Actinomycetes; Acs Med.Chem.Lett., 5:346-, 2014; PubMed: 24900839; DOI: 10.1021/ML4004588

Experimental method

X-RAY DIFFRACTION (2.1 Å)