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PDB: 1498 件

6MHG
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Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts
分子名称: Fab311 heavy chain, Fab311 light chain, circumsporozoite protein
著者Cottrell, C.A, Torres, J.L, Ward, A.B.
登録日2018-09-17
公開日2018-10-31
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Cryo-EM structure ofP. falciparumcircumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts.
Sci Adv, 4, 2018
2GPV
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BU of 2gpv by Molmil
Estrogen Related Receptor-gamma ligand binding domain complexed with 4-hydroxy-tamoxifen and a SMRT peptide
分子名称: 4-HYDROXYTAMOXIFEN, Estrogen-related receptor gamma, Nuclear receptor corepressor 2
著者Wang, L, Zuercher, W.J, Consler, T.G, Lambert, M.H, Miller, A.B, Osband-miller, L.A, McKee, D.D, Willson, T.M, Nolte, R.T.
登録日2006-04-18
公開日2006-09-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.
J.Biol.Chem., 281, 2006
5KBL
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Candida Albicans Superoxide Dismutase 5 (SOD5), E110Q Mutant
分子名称: COPPER (I) ION, Cell surface Cu-only superoxide dismutase 5, SULFATE ION
著者Galaleldeen, A, Peterson, R.L, Villarreal, J, Taylor, A.B, Hart, P.J.
登録日2016-06-03
公開日2016-08-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.414 Å)
主引用文献The Phylogeny and Active Site Design of Eukaryotic Copper-only Superoxide Dismutases.
J.Biol.Chem., 291, 2016
5KEM
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EBOV sGP in complex with variable Fab domains of IgGs c13C6 and BDBV91
分子名称: BDBV91 variable Fab domain heavy chain, BDBV91 variable Fab domain light chain, Ebola secreted glycoprotein, ...
著者Pallesen, J, Murin, C.D, de Val, N, Cottrell, C.A, Hastie, K.M, Turner, H.L, Fusco, M.L, Flyak, A.I, Zeitlin, L, Crowe Jr, J.E, Andersen, K.G, Saphire, E.O, Ward, A.B.
登録日2016-06-09
公開日2016-09-07
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (5.5 Å)
主引用文献Structures of Ebola virus GP and sGP in complex with therapeutic antibodies.
Nat Microbiol, 1, 2016
5K9J
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Crystal structure of multidonor HV6-1-class broadly neutralizing Influenza A antibody 56.a.09 isolated following H5 immunization.
分子名称: 56.a.09 heavy chain, 56.a.09 light chain, POLYETHYLENE GLYCOL (N=34)
著者Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D.
登録日2016-05-31
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.904 Å)
主引用文献Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.
Cell, 166, 2016
5KBM
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Candida Albicans Superoxide Dismutase 5 (SOD5), D113N Mutant
分子名称: COPPER (I) ION, Cell surface Cu-only superoxide dismutase 5, SULFATE ION
著者Galaleldeen, A, Peterson, R.L, Villarreal, J, Taylor, A.B, Hart, P.J.
登録日2016-06-03
公開日2016-08-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.416 Å)
主引用文献The Phylogeny and Active Site Design of Eukaryotic Copper-only Superoxide Dismutases.
J.Biol.Chem., 291, 2016
5KD2
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BT_4244 metallopeptidase from Bacteroides thetaiotaomicron
分子名称: 1,2-ETHANEDIOL, ZINC ION, metallopeptidase
著者Noach, I, Boraston, A.B.
登録日2016-06-07
公開日2017-01-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Recognition of protein-linked glycans as a determinant of peptidase activity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5KDJ
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ZmpB metallopeptidase from Clostridium perfringens
分子名称: F5/8 type C domain protein, GLYCEROL, SODIUM ION, ...
著者Noach, I, Ficko-Blean, E, Stuart, C, Boraston, A.B.
登録日2016-06-08
公開日2017-01-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Recognition of protein-linked glycans as a determinant of peptidase activity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5K78
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Dbr1 in complex with 16-mer branched RNA
分子名称: FE (II) ION, RNA lariat debranching enzyme, putative, ...
著者Clark, N.E, Taylor, A.B, Hart, P.J.
登録日2016-05-25
公開日2016-12-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献The RNA lariat debranching enzyme Dbr1: metal dependence and branched RNA co-crystal structures
Proc.Natl.Acad.Sci.USA, 2016
2GNU
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BU of 2gnu by Molmil
The crystallization of reaction center from Rhodobacter sphaeroides occurs via a new route
分子名称: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ...
著者Wadsten, P, Woehri, A.B, Snijder, A, Katona, G, Gardiner, A.T, Cogdell, R.J, Neutze, R, Engstroem, S.
登録日2006-04-11
公開日2006-11-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Lipidic sponge phase crystallization of membrane proteins
J.Mol.Biol., 364, 2006
2GPP
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Estrogen Related Receptor-gamma ligand binding domain complexed with a RIP140 peptide and synthetic ligand GSK4716
分子名称: 4-HYDROXY-N'-(4-ISOPROPYLBENZYL)BENZOHYDRAZIDE, Estrogen-related receptor gamma, Nuclear receptor-interacting protein 1
著者Wang, L, Zuercher, W.J, Consler, T.G, Lambert, M.H, Miller, A.B, Osband-miller, L.A, McKee, D.D, Willson, T.M, Nolte, R.T.
登録日2006-04-18
公開日2006-09-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.
J.Biol.Chem., 281, 2006
6MFE
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BU of 6mfe by Molmil
Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0000773 (Compound 11g) Complex
分子名称: (2-nitro-4-{[(3S)-1-{[4-(trifluoromethoxy)phenyl]methyl}pyrrolidin-3-yl]amino}phenyl)methanol, ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase oxamniquine resistance protein
著者Taylor, A.B.
登録日2018-09-10
公開日2018-10-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.444 Å)
主引用文献Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents.
ACS Med Chem Lett, 9, 2018
6MBX
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CRYSTAL STRUCTURE OF MUSKMELON ALLERGEN CUC M 2
分子名称: Profilin
著者Kapingidza, A.B, Hyduke, N.P, Chruszcz, M.
登録日2018-08-30
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Comparative structural and thermal stability studies of Cuc m 2.0101, Art v 4.0101 and other allergenic profilins.
Mol.Immunol., 114, 2019
4KN6
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BU of 4kn6 by Molmil
Crystal structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with 6-fluoro-3-hydroxy-2-pyrazinecarboxamide (T-705) ribose-5'-monophosphate
分子名称: 6-fluoro-3-oxo-4-(5-O-phosphono-beta-D-ribofuranosyl)-3,4-dihydropyrazine-2-carboxamide, Hypoxanthine-guanine phosphoribosyltransferase
著者Naesens, L, Guddat, L, Keough, D, van Kuilenburg, A.B.P, Meijer, J, Vande Voorde, J, Balzarini, J.
登録日2013-05-08
公開日2013-08-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.728 Å)
主引用文献Role of human hypoxanthine Guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir).
Mol.Pharmacol., 84, 2013
6MAR
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BU of 6mar by Molmil
HIV-1 Envelope Glycoprotein Clone BG505 delCT N332T in complex with broadly neutralizing antibody Fab PGT151
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Berndsen, Z.T, Ward, A.B.
登録日2018-08-28
公開日2018-09-26
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer.
Nat Commun, 9, 2018
6MB3
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BU of 6mb3 by Molmil
Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts
分子名称: Fab311 heavy chain, Fab311 light chain, Plasmodium falciparum recombinant shortened CSP
著者Cottrell, C.A, Torres, J.L, Ward, A.B.
登録日2018-08-29
公開日2018-10-31
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Cryo-EM structure ofP. falciparumcircumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts.
Sci Adv, 4, 2018
6MGV
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Structure of mechanically activated ion channel OSCA1.2 in nanodisc
分子名称: Calcium permeable stress-gated cation channel 1
著者Jojoa-Cruz, S, Saotome, K, Patapoutian, A, Ward, A.B.
登録日2018-09-15
公開日2018-11-14
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structure of the mechanically activated ion channel OSCA1.2.
Elife, 7, 2018
2H2N
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BU of 2h2n by Molmil
Crystal structure of human soluble calcium-activated nucleotidase (SCAN) with calcium ion
分子名称: ACETATE ION, CALCIUM ION, Soluble calcium-activated nucleotidase 1
著者Yang, M, Horii, K, Herr, A.B, Kirley, T.L.
登録日2006-05-19
公開日2006-07-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Calcium-dependent dimerization of human soluble calcium activated nucleotidase: characterization of the dimer interface.
J.Biol.Chem., 281, 2006
2H2U
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Crystal structure of the E130Y mutant of human soluble calcium-activated nucleotidase (SCAN) with calcium ion
分子名称: CALCIUM ION, Soluble calcium-activated nucleotidase 1
著者Yang, M, Horii, K, Herr, A.B, Kirley, T.L.
登録日2006-05-19
公開日2006-07-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Calcium-dependent dimerization of human soluble calcium activated nucleotidase: characterization of the dimer interface.
J.Biol.Chem., 281, 2006
2GPO
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Estrogen Related Receptor-gamma ligand binding domain complexed with a synthetic peptide from RIP140
分子名称: Estrogen-related receptor gamma, Nuclear receptor-interacting protein 1
著者Wang, L, Zuercher, W.J, Consler, T.G, Lambert, M.H, Miller, A.B, Osband-miller, L.A, McKee, D.D, Willson, T.M, Nolte, R.T.
登録日2006-04-18
公開日2006-09-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.
J.Biol.Chem., 281, 2006
6MLM
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H7 HA0 in complex with Fv from H7.5 IgG
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain Fv of H7.5 Fab, Hemagglutinin HA1 chain, ...
著者Pallesen, J, Turner, H.L, Ward, A.B.
登録日2018-09-27
公開日2019-02-20
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains.
PLoS Biol., 17, 2019
4JDN
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Secreted Chlamydial Protein PGP3, C-terminal Domain
分子名称: GLYCEROL, POTASSIUM ION, Virulence plasmid protein pGP3-D
著者Galaleldeen, A, Taylor, A.B, Chen, D, Holloway, S.P, Zhong, G, Hart, P.J.
登録日2013-02-25
公開日2013-06-05
最終更新日2013-10-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the Chlamydia trachomatis immunodominant antigen Pgp3.
J.Biol.Chem., 288, 2013
2CNJ
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NMR studies on the interaction of Insulin-Growth Factor II (IGF-II) with IGF2R domain 11
分子名称: CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR
著者Williams, C, Prince, S, Zaccheo, O, Hassan, A.B, Crosby, J, Crump, M.
登録日2006-05-22
公開日2007-05-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Insights Into the Interaction of Insulin-Like Growth Factor 2 with Igf2R Domain 11.
Structure, 15, 2007
4K1C
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VCX1 Calcium/Proton Exchanger
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, IODIDE ION, ...
著者Waight, A.B, Pedersen, B.P, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP)
登録日2013-04-04
公開日2013-05-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for alternating access of a eukaryotic calcium/proton exchanger.
Nature, 499, 2013
2GPU
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Estrogen Related Receptor-gamma ligand binding domain complexed with 4-hydroxy-tamoxifen
分子名称: 4-HYDROXYTAMOXIFEN, Estrogen-related receptor gamma
著者Wang, L, Zuercher, W.J, Consler, T.G, Lambert, M.H, Miller, A.B, Osband-Miller, L.A, McKee, D.D, Willson, T.M, Nolte, R.T.
登録日2006-04-18
公開日2006-09-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.
J.Biol.Chem., 281, 2006

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