2GPV

Estrogen Related Receptor-gamma ligand binding domain complexed with 4-hydroxy-tamoxifen and a SMRT peptide

Summary for 2GPV

• Entry DOI: 10.2210/pdb2gpv/pdb
• Related: 2GP7 2GPO 2GPP 2GPU
• Descriptor: Estrogen-related receptor gamma, Nuclear receptor corepressor 2, 4-HYDROXYTAMOXIFEN, ... (4 entities in total)
• Functional Keywords: estrogen related receptor, err, errg, esrrg, nuclear receptor, steroid receptor, smrt, tamoxifen, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 9
• Total formula weight: 166631.32

Authors

Wang, L.,Zuercher, W.J.,Consler, T.G.,Lambert, M.H.,Miller, A.B.,Osband-miller, L.A.,McKee, D.D.,Willson, T.M.,Nolte, R.T. (deposition date: 2006-04-18, release date: 2006-09-26, Last modification date: 2023-08-30)

• Primary citation: Wang, L.,Zuercher, W.J.,Consler, T.G.,Lambert, M.H.,Miller, A.B.,Orband-Miller, L.A.,McKee, D.D.,Willson, T.M.,Nolte, R.T.; X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.; J.Biol.Chem., 281:37773-37781, 2006; PubMed: 16990259; DOI: 10.1074/jbc.M608410200

Experimental method

X-RAY DIFFRACTION (2.85 Å)