4QT7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qt7 by Molmil](/molmil-images/mine/4qt7) | |
7ZHS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zhs by Molmil](/molmil-images/mine/7zhs) | 3D reconstruction of the cylindrical assembly of DnaJA2 delta G/F by imposing D5 symmetry | Descriptor: | Ubiquitin-like protein SMT3,DnaJ homolog subfamily A member 2, ZINC ION | Authors: | Cuellar, J, Velasco-Carneros, L, Santiago, C, Martin-Benito, J, Valpuesta, J, Muga, A. | Deposit date: | 2022-04-07 | Release date: | 2023-07-26 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | The self-association equilibrium of DNAJA2 regulates its interaction with unfolded substrate proteins and with Hsc70. Nat Commun, 14, 2023
|
|
6UHR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uhr by Molmil](/molmil-images/mine/6uhr) | Crystal Structure of C148 mGFP-scDNA-2 | Descriptor: | C148 mGFP-scDNA-2 | Authors: | Winegar, P.W, Hayes, O.G, McMillan, J.R, Figg, C.A, Focia, P.J, Mirkin, C.A. | Deposit date: | 2019-09-27 | Release date: | 2020-03-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | DNA-Directed Protein Packing within Single Crystals. Chem, 6, 2020
|
|
6U9F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u9f by Molmil](/molmil-images/mine/6u9f) | Structure of Francisella PdpA-VgrG Complex, Lidded | Descriptor: | PdpA, VgrG | Authors: | Yang, X, Clemens, D.L, Lee, B.-Y, Cui, Y.X, Horwitz, M.A, Zhou, Z.H. | Deposit date: | 2019-09-08 | Release date: | 2019-10-23 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.35 Å) | Cite: | Atomic Structure of the Francisella T6SS Central Spike Reveals a Unique alpha-Helical Lid and a Putative Cargo. Structure, 27, 2019
|
|
6E7M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e7m by Molmil](/molmil-images/mine/6e7m) | |
7TGK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tgk by Molmil](/molmil-images/mine/7tgk) | Crystal structure of ATP bound DesD, the desferrioxamine synthetase from the Streptomyces griseoflavus ferrimycin biosynthetic pathway | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Patel, K.D, Gulick, A.M. | Deposit date: | 2022-01-07 | Release date: | 2022-07-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | An acyl-adenylate mimic reveals the structural basis for substrate recognition by the iterative siderophore synthetase DesD. J.Biol.Chem., 298, 2022
|
|
6S74
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s74 by Molmil](/molmil-images/mine/6s74) | Crystal structure of CARM1 in complex with inhibitor UM305 | Descriptor: | (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[[3-azanylpropyl-[3-(pyrimidin-2-ylamino)propyl]amino]methyl]oxolane-3,4-diol, GLYCEROL, Histone-arginine methyltransferase CARM1 | Authors: | Gunnell, E.A, Muhsen, U, Dowden, J, Dreveny, I. | Deposit date: | 2019-07-04 | Release date: | 2020-03-04 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and biochemical evaluation of bisubstrate inhibitors of protein arginine N-methyltransferases PRMT1 and CARM1 (PRMT4). Biochem.J., 477, 2020
|
|
4XDO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xdo by Molmil](/molmil-images/mine/4xdo) | Crystal structure of human KDM4C catalytic domain with OGA | Descriptor: | 1,2-ETHANEDIOL, FE (III) ION, Lysine-specific demethylase 4C, ... | Authors: | Swinger, K.K, Boriack-Sjodin, P.A. | Deposit date: | 2014-12-19 | Release date: | 2015-03-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | A High-Throughput Mass Spectrometry Assay Coupled with Redox Activity Testing Reduces Artifacts and False Positives in Lysine Demethylase Screening. J Biomol Screen, 20, 2015
|
|
5KIF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5kif by Molmil](/molmil-images/mine/5kif) | Structural impact of single ribonucleotides in DNA | Descriptor: | DNA (5'-D(*CP*TP*AP*CP*CP*GP*GP*AP*T)-3'), DNA/RNA (5'-D(*AP*TP*CP*C)-R(P*G)-D(P*GP*TP*AP*G)-3') | Authors: | Evich, M, Spring-Connell, A.M, Storici, F, Germann, M.W. | Deposit date: | 2016-06-16 | Release date: | 2016-08-24 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural Impact of Single Ribonucleotide Residues in DNA. Chembiochem, 17, 2016
|
|
7QRL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qrl by Molmil](/molmil-images/mine/7qrl) | |
5KE1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ke1 by Molmil](/molmil-images/mine/5ke1) | Structure of a C-terminal fragment of the IcsA/VirG passenger-domain | Descriptor: | NICKEL (II) ION, Outer membrane protein IcsA autotransporter | Authors: | Leupold, S, Scrima, A. | Deposit date: | 2016-06-09 | Release date: | 2017-03-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insights into the architecture of the Shigella flexneri virulence factor IcsA/VirG and motifs involved in polar distribution and secretion. J. Struct. Biol., 198, 2017
|
|
6HT9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ht9 by Molmil](/molmil-images/mine/6ht9) | Mouse fetuin-B in complex with crayfish astacin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Astacin, ... | Authors: | Gomis-Ruth, F.X, Goulas, T, Guevara, T, Cuppari, A. | Deposit date: | 2018-10-03 | Release date: | 2019-03-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition. Iucrj, 6, 2019
|
|
6ED2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ed2 by Molmil](/molmil-images/mine/6ed2) | Faecalibacterium prausnitzii beta-glucuronidase | Descriptor: | FORMIC ACID, GLYCEROL, Glycosyl hydrolase family 2, ... | Authors: | Pellock, S.J, Biernat, K.A, Redinbo, M.R. | Deposit date: | 2018-08-08 | Release date: | 2019-02-13 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases. Sci Rep, 9, 2019
|
|
5JOP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jop by Molmil](/molmil-images/mine/5jop) | Crystal structure of anti-glycan antibody Fab14.22 in complex with Streptococcus pneumoniae serotype 14 tetrasaccharide at 1.75 A | Descriptor: | Fab 14.22 light chain, Fab14.22 heavy chain, GLYCEROL, ... | Authors: | Sarkar, A, Irimia, A, Teyton, L, Wilson, I.A. | Deposit date: | 2016-05-02 | Release date: | 2017-03-22 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | T cells control the generation of nanomolar-affinity anti-glycan antibodies. J. Clin. Invest., 127, 2017
|
|
7QX3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qx3 by Molmil](/molmil-images/mine/7qx3) | Structure of the transaminase TR2E2 with EOS | Descriptor: | 2-azanylethyl hydrogen sulfate, Aminotransferase TR2 | Authors: | Roda, S, Fernandez-Lopez, L, Benedens, M, Bollinger, A, Thies, S, Schumacher, J, Coscolin, C, Kazemi, M, Santiago, G, Gertzen, C.G, Gonzalez-Alfonso, J, Plou, F.J, Jaeger, K.E, Smits, S.H, Ferrer, M, Guallar, V. | Deposit date: | 2022-01-26 | Release date: | 2023-08-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | A Plurizyme with Transaminase and Hydrolase Activity Catalyzes Cascade Reactions. Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
7QX0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qx0 by Molmil](/molmil-images/mine/7qx0) | Transaminase Structure of Plurienzyme (Tr2E2) in complex with PLP | Descriptor: | Aminotransferase TR2, PYRIDOXAL-5'-PHOSPHATE | Authors: | Roda, S, Fernandez-Lopez, L, Benedens, M, Bollinger, A, Thies, S, Schumacher, J, Coscolin, C, Kazemi, M, Santiago, G, Gertzen, C.G, Gonzalez-Alfonso, J, Plou, F.J, Jaeger, K.E, Smits, S.H, Ferrer, M, Guallar, V. | Deposit date: | 2022-01-26 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | A Plurizyme with Transaminase and Hydrolase Activity Catalyzes Cascade Reactions. Angew Chem Int Ed Engl, 61, 2022
|
|
6ECA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6eca by Molmil](/molmil-images/mine/6eca) | Lactobacillus rhamnosus Beta-glucuronidase | Descriptor: | Beta-glucuronidase, CHLORIDE ION, GLYCEROL | Authors: | Biernat, K.A, Pellock, S.J, Bhatt, A.P, Bivins, M.M, Walton, W.G, Tran, B.N.T, Wei, L, Snider, M.C, Cesmat, A.P, Tripathy, A, Erie, D.A, Redinbo, M.R.R. | Deposit date: | 2018-08-07 | Release date: | 2019-02-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.853 Å) | Cite: | Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases. Sci Rep, 9, 2019
|
|
5WYE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wye by Molmil](/molmil-images/mine/5wye) | |
6ULZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ulz by Molmil](/molmil-images/mine/6ulz) | Adenylation domain of the initiation module of LgrA mutant P483M | Descriptor: | 3-METHYL-2-OXOBUTANOIC ACID, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, FORMIC ACID, ... | Authors: | Chiche-Lapierre, C, Alonzo, D.A, Schmeing, T.M. | Deposit date: | 2019-10-08 | Release date: | 2020-02-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis. Nat.Chem.Biol., 16, 2020
|
|
6ZUB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zub by Molmil](/molmil-images/mine/6zub) | Cu nitrite reductase from Achromobacter cycloclastes: MSOX series at 170K, dose point 2 | Descriptor: | COPPER (II) ION, Copper-containing nitrite reductase, MALONATE ION, ... | Authors: | Hough, M.A, Antonyuk, S.V, Strange, R.W, Hasnain, S.S. | Deposit date: | 2020-07-22 | Release date: | 2021-06-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Nature of the copper-nitrosyl intermediates of copper nitrite reductases during catalysis. Chem Sci, 11, 2020
|
|
4XG0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xg0 by Molmil](/molmil-images/mine/4xg0) | Crystal structure of a domain of unknown function (DUF1537) from Bordetella bronchiseptica (BB3215), Target EFI-511620, with bound citrate, domain swapped dimer, space group C2221 | Descriptor: | CHLORIDE ION, CITRIC ACID, SULFATE ION, ... | Authors: | Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2014-12-30 | Release date: | 2015-03-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
5JOX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jox by Molmil](/molmil-images/mine/5jox) | Bacteroides ovatus Xyloglucan PUL GH43A in complex with AraDNJ | Descriptor: | 1,4-DIDEOXY-1,4-IMINO-L-ARABINITOL, Non-reducing end alpha-L-arabinofuranosidase BoGH43A | Authors: | Thompson, A.J, Hemsworth, G.R, Stepper, J, Sobala, L.F, Coyle, T, Larsbrink, J, Spadiut, O, Stubbs, K.A, Brumer, H, Davies, G.J. | Deposit date: | 2016-05-03 | Release date: | 2016-08-10 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut. Open Biology, 6, 2016
|
|
4R0V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4r0v by Molmil](/molmil-images/mine/4r0v) | [FeFe]-hydrogenase Oxygen Inactivation is Initiated by the Modification and Degradation of the H cluster 2Fe Subcluster | Descriptor: | ARSENIC, CHLORIDE ION, Fe-hydrogenase, ... | Authors: | Swanson, S.D, Ratzloff, M.W, Mulder, D.W, Artz, J.H, Ghose, S, Hoffman, A, White, S, Zadvornyy, O.A, Broderick, J.B, Bothner, B, King, P.W, Peters, J.W. | Deposit date: | 2014-08-01 | Release date: | 2015-01-28 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | [FeFe]-Hydrogenase Oxygen Inactivation Is Initiated at the H Cluster 2Fe Subcluster. J.Am.Chem.Soc., 137, 2015
|
|
6ZUT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zut by Molmil](/molmil-images/mine/6zut) | Cu nitrite reductase MSOX series at 170K, dose point 5 | Descriptor: | COPPER (II) ION, Copper-containing nitrite reductase, MALONATE ION, ... | Authors: | Hough, M.A, Anyonyuk, S.V, Strange, R.W, Hasnain, S.S. | Deposit date: | 2020-07-23 | Release date: | 2021-06-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Nature of the copper-nitrosyl intermediates of copper nitrite reductases during catalysis. Chem Sci, 11, 2020
|
|
6ALF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6alf by Molmil](/molmil-images/mine/6alf) | CryoEM structure of crosslinked E.coli RNA polymerase elongation complex | Descriptor: | DNA (29-MER), DNA (5'-D(*GP*GP*GP*CP*TP*AP*AP*TP*GP*AP*CP*GP*GP*CP*GP*AP*AP*TP*AP*CP*CP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Kang, J.Y, Darst, S.A. | Deposit date: | 2017-08-07 | Release date: | 2017-08-16 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis of transcription arrest by coliphage HK022 Nun in anEscherichia coliRNA polymerase elongation complex. Elife, 6, 2017
|
|