6E7M

Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28C mutant of human Cellular Retinol Binding Protein II

Summary for 6E7M

Entry DOI	10.2210/pdb6e7m/pdb
Descriptor	Retinol-binding protein 2, ACETATE ION, GLYCEROL, ... (5 entities in total)
Functional Keywords	retinol, ilbp, protein switch, lipid binding protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	64005.65
Authors	Ghanbarpour, A.,Geiger, J. (deposition date: 2018-07-26, release date: 2019-10-16, Last modification date: 2023-10-11)
Primary citation	Ghanbarpour, A.,Pinger, C.,Esmatpour Salmani, R.,Assar, Z.,Santos, E.M.,Nosrati, M.,Pawlowski, K.,Spence, D.,Vasileiou, C.,Jin, X.,Borhan, B.,Geiger, J.H. Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches. J.Am.Chem.Soc., 141:17125-17132, 2019 Cited by PubMed: 31557439 DOI: 10.1021/jacs.9b04664 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation