6X9A
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6U5J
| CryoEM Structure of Pyocin R2 - postcontracted - collar | Descriptor: | Collar PA0615, Sheath PA0622 | Authors: | Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H. | Deposit date: | 2019-08-27 | Release date: | 2020-04-15 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Action of a minimal contractile bactericidal nanomachine. Nature, 580, 2020
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1NNQ
| rubrerythrin from Pyrococcus furiosus Pfu-1210814 | Descriptor: | Rubrerythrin, ZINC ION | Authors: | Liu, Z.-J, Tempel, W, Schubot, F.D, Shah, A, Arendall III, W.B, Rose, J.P, Richardson, D.C, Richardson, J.S, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2003-01-14 | Release date: | 2004-03-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural genomics of Pyrococcus furiosus: X-ray crystallography reveals 3D domain swapping in rubrerythrin Proteins, 57, 2004
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7CG3
| Staggered ring conformation of CtHsp104 (Hsp104 from Chaetomium Thermophilum) | Descriptor: | Heat shock protein 104 | Authors: | Inoue, Y, Hanazono, Y, Noi, K, Kawamoto, A, Kimatsuka, M, Harada, R, Takeda, K, Iwamasa, N, Shibata, K, Noguchi, K, Shigeta, Y, Namba, K, Ogura, T, Miki, K, Shinohara, K, Yohda, M. | Deposit date: | 2020-06-30 | Release date: | 2021-04-28 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Split conformation of Chaetomium thermophilum Hsp104 disaggregase. Structure, 29, 2021
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4GWO
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7MQQ
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5CG1
| Crystal structure of E. coli FabI bound to the carbamoylated benzodiazaborine inhibitor 14b. | Descriptor: | 1-hydroxy-2,3,1-benzodiazaborinine-2(1H)-carboxamide, Enoyl-[acyl-carrier-protein] reductase [NADH] FabI, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Jordan, C.A, Vey, J.L. | Deposit date: | 2015-07-09 | Release date: | 2015-12-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Crystallographic insights into the structure-activity relationships of diazaborine enoyl-ACP reductase inhibitors. Acta Crystallogr.,Sect.F, 71, 2015
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6S71
| Crystal structure of CARM1 in complex with inhibitor WH5C | Descriptor: | (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-(5-carbamimidamidopentyl)amino]-2-azanyl-butanoic acid, GLYCEROL, Histone-arginine methyltransferase CARM1 | Authors: | Gunnell, E.A, Muhsen, U, Dowden, J, Dreveny, I. | Deposit date: | 2019-07-04 | Release date: | 2020-03-04 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.062 Å) | Cite: | Structural and biochemical evaluation of bisubstrate inhibitors of protein arginine N-methyltransferases PRMT1 and CARM1 (PRMT4). Biochem.J., 477, 2020
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2WBU
| CRYSTAL STRUCTURE OF THE ZINC FINGER DOMAIN OF KLF4 BOUND TO ITS TARGET DNA | Descriptor: | 5'-D(*DGP*DAP*DGP*DGP*DCP*DGP*DTP* DGP*DGP*DC)-3', 5'-D(*DGP*DCP*DCP*DAP*DCP*DGP*DCP* DCP*DTP*DC)-3', KRUEPPEL-LIKE FACTOR 4, ... | Authors: | Schuetz, A, Zocher, G, Carstanjen, D, Heinemann, U. | Deposit date: | 2009-03-05 | Release date: | 2010-04-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Structure of the Klf4 DNA-Binding Domain Links to Self-Renewal and Macrophage Differentiation. Cell.Mol.Life Sci., 68, 2011
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6S7B
| Crystal structure of CARM1 in complex with inhibitor UM249 | Descriptor: | 1-[4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-(3-azanylpropyl)amino]butyl]guanidine, Histone-arginine methyltransferase CARM1 | Authors: | Gunnell, E.A, Muhsen, U, Dowden, J, Dreveny, I. | Deposit date: | 2019-07-04 | Release date: | 2020-03-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.659 Å) | Cite: | Structural and biochemical evaluation of bisubstrate inhibitors of protein arginine N-methyltransferases PRMT1 and CARM1 (PRMT4). Biochem.J., 477, 2020
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8B2G
| SH3-like domain from Penicillium virgatum muramidase | Descriptor: | 1,2-ETHANEDIOL, SH3b domain-containing protein, ZINC ION | Authors: | Moroz, O.V, Blagova, E, Lebedev, A.A, Skov, L.K, Pache, R.A, Schnorr, K.M, Kiemer, L, Nymand-Grarup, S, Ming, L, Ye, L, Klausen, M, Cohn, M.T, Schmidt, E.G.W, Davies, G.J, Wilson, K.S. | Deposit date: | 2022-09-13 | Release date: | 2023-07-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Module walking using an SH3-like cell-wall-binding domain leads to a new GH184 family of muramidases. Acta Crystallogr D Struct Biol, 79, 2023
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6S7N
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5JI2
| HslU L199Q in HslUV complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV, ... | Authors: | Grant, R.A, Sauer, R.T, Schmitz, K.R, Baytshtok, V. | Deposit date: | 2016-04-21 | Release date: | 2016-11-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.307 Å) | Cite: | A Structurally Dynamic Region of the HslU Intermediate Domain Controls Protein Degradation and ATP Hydrolysis. Structure, 24, 2016
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5JLG
| The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and compound I, a piano-stool organometallic Ru(II) arene compound containing an O,S-chelating ligand | Descriptor: | DIMETHYL SULFOXIDE, RUTHENIUM ION, Ribonuclease pancreatic, ... | Authors: | Ferraro, G, Merlino, A. | Deposit date: | 2016-04-27 | Release date: | 2016-08-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Unusual mode of protein binding by a cytotoxic pi-arene ruthenium(ii) piano-stool compound containing an O,S-chelating ligand. Dalton Trans, 45, 2016
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6RTX
| Crystal structure of the Patched-1 (PTCH1) ectodomain 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein patched homolog 1 | Authors: | Rudolf, A.F, Kowatsch, C, El Omari, K, Malinauskas, T, Kinnebrew, M, Ansell, T.B, Bishop, B, Pardon, E, Schwab, R.A, Qian, M, Duman, R, Covey, D.F, Steyaert, J, Wagner, A, Sansom, M.S.P, Rohatgi, R, Siebold, C. | Deposit date: | 2019-05-27 | Release date: | 2019-10-02 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism. Nat.Chem.Biol., 15, 2019
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4DTZ
| cytochrome P450 BM3h-8C8 MRI sensor bound to dopamine | Descriptor: | L-DOPAMINE, PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 BM3 variant 8C8 | Authors: | Brustad, E.M, Lelyveld, V.S, Snow, C.D, Crook, N, Martinez, F.M, Scholl, T.J, Jasanoff, A, Arnold, F.H. | Deposit date: | 2012-02-21 | Release date: | 2012-06-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure-guided directed evolution of highly selective p450-based magnetic resonance imaging sensors for dopamine and serotonin. J.Mol.Biol., 422, 2012
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3BEE
| Crystal structure of putative YfrE protein from Vibrio parahaemolyticus | Descriptor: | 1,2-ETHANEDIOL, Putative YfrE protein | Authors: | Chang, C, Hatzos, C, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-11-16 | Release date: | 2007-12-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of putative YfrE protein from Vibrio parahaemolyticus. To be Published
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6RUJ
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4DUP
| Crystal Structure of a quinone oxidoreductase from Rhizobium etli CFN 42 | Descriptor: | quinone oxidoreductase | Authors: | Kumaran, D, Rice, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2012-02-22 | Release date: | 2012-03-07 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal Structure of a quinone oxidoreductase from Rhizobium etli CFN 42 To be Published
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3RLW
| Human Thrombin in complex with MI328 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Hirudin variant-2, ... | Authors: | Biela, A, Heine, A, Klebe, G. | Deposit date: | 2011-04-20 | Release date: | 2012-04-25 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Ligand binding stepwise disrupts water network in thrombin: enthalpic and entropic changes reveal classical hydrophobic effect J.Med.Chem., 55, 2012
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8E9L
| Crystal structure of E. coli aspartate aminotransferase mutant VFIT in the ligand-free form at 278 K | Descriptor: | Aspartate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION | Authors: | Chica, R.A, St-Jacques, A.D, Rodriguez, J.M, Thompson, M.C. | Deposit date: | 2022-08-26 | Release date: | 2022-10-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Computational remodeling of an enzyme conformational landscape for altered substrate selectivity. Nat Commun, 14, 2023
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7U5G
| ACS122 Fab | Descriptor: | ACS122 Fab Heavy chain, ACS122 Fab Light chain | Authors: | Farokhi, E, Stanfield, R.L, Wilson, I.A. | Deposit date: | 2022-03-02 | Release date: | 2022-11-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Complementary antibody lineages achieve neutralization breadth in an HIV-1 infected elite neutralizer. Plos Pathog., 18, 2022
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8B2F
| SH3-like cell wall binding domain of the GH24 family muramidase from Trichophaea saccata in complex with triglycine | Descriptor: | 1,2-ETHANEDIOL, GLY-GLY-GLY, SH3-like cell wall binding domain-containing protein, ... | Authors: | Moroz, O.V, Blagova, E, Lebedev, A.A, Skov, L.K, Pache, R.A, Schnorr, K.M, Kiemer, L, Nymand-Grarup, S, Ming, L, Ye, L, Klausen, M, Cohn, M.T, Schmidt, E.G.W, Davies, G.J, Wilson, K.S. | Deposit date: | 2022-09-13 | Release date: | 2023-07-19 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.183 Å) | Cite: | Module walking using an SH3-like cell-wall-binding domain leads to a new GH184 family of muramidases. Acta Crystallogr D Struct Biol, 79, 2023
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4YS9
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4GXB
| Structure of the SNX17 atypical FERM domain bound to the NPxY motif of P-selectin | Descriptor: | GLYCEROL, P-selectin, Sorting nexin-17 | Authors: | Ghai, R, Bugarcic, A, Liu, H, Norwood, S.J, Li, S.S, Teasdale, R.D, Collins, B.M. | Deposit date: | 2012-09-04 | Release date: | 2013-03-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. Proc.Natl.Acad.Sci.USA, 110, 2013
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