6EC0
| Crystal structure of the wild-type heterocomplex between coil 1B domains of human intermediate filament proteins keratin 1 (KRT1) and keratin 10 (KRT10) | 分子名称: | CADMIUM ION, COBALT (II) ION, Keratin 1, ... | 著者 | Eldirany, S.A, Lomakin, I.B, Bunick, C.G. | 登録日 | 2018-08-07 | 公開日 | 2019-05-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.983 Å) | 主引用文献 | Human keratin 1/10-1B tetramer structures reveal a knob-pocket mechanism in intermediate filament assembly. Embo J., 38, 2019
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7SAH
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6HYF
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4ZAR
| Crystal Structure of Proteinase K from Engyodontium albuminhibited by METHOXYSUCCINYL-ALA-ALA-PRO-PHE-CHLOROMETHYL KETONE at 1.15 A resolution | 分子名称: | CALCIUM ION, METHOXYSUCCINYL-ALA-ALA-PRO-PHE-CHLOROMETHYL KETONE, bound form, ... | 著者 | Sawaya, M.R, Cascio, D, Collazo, M, Bond, C, Cohen, A, DeNicola, A, Eden, K, Jain, K, Leung, C, Lubock, N, McCormick, J, Rosinski, J, Spiegelman, L, Athar, Y, Tibrewal, N, Winter, J, Solomon, S. | 登録日 | 2015-04-14 | 公開日 | 2015-05-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Crystal Structure of Proteinase K from Engyodontium album inhibited by METHOXYSUCCINYL-ALA-ALA-PRO-PHE-CHLOROMETHYL KETONE at 1.15 A resolution to be published
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6RAH
| Heterodimeric ABC exporter TmrAB in ATP-bound outward-facing open conformation | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance ABC transporter ATP-binding and permease protein, ... | 著者 | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | 登録日 | 2019-04-06 | 公開日 | 2019-07-31 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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5YZO
| Crystal structure of S9 peptidase mutant (S514A) from Deinococcus radiodurans R1 | 分子名称: | Acyl-peptide hydrolase, putative, DIMETHYL SULFOXIDE, ... | 著者 | Yadav, P, Jamdar, S.N, Kumar, A, Ghosh, B, Makde, R.D. | 登録日 | 2017-12-15 | 公開日 | 2018-11-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Carboxypeptidase in prolyl oligopeptidase family: Unique enzyme activation and substrate-screening mechanisms. J.Biol.Chem., 294, 2019
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4UB3
| DNA polymerase beta closed product complex with a templating cytosine and 8-oxodGMP, 60 s | 分子名称: | 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*(8OG))-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | 著者 | Freudenthal, B.D, Wilson, S.H, Beard, W.A. | 登録日 | 2014-08-11 | 公開日 | 2014-11-12 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide. Nature, 517, 2015
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6RAS
| Pmar-Lig_Pre. | 分子名称: | ADENOSINE MONOPHOSPHATE, ATP-dependent DNA ligase, DNA, ... | 著者 | Leiros, H.K.S, Williamson, A. | 登録日 | 2019-04-07 | 公開日 | 2019-07-10 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural intermediates of a DNA-ligase complex illuminate the role of the catalytic metal ion and mechanism of phosphodiester bond formation. Nucleic Acids Res., 47, 2019
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6W8Z
| Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments | 分子名称: | Nonstructural polyprotein, methyl 2-oxo-1,2-dihydroquinazoline-4-carboxylate | 著者 | Zhang, S, Garzan, A, Pathak, A.K, Augelli-Szafran, C.E, Wu, M. | 登録日 | 2020-03-21 | 公開日 | 2021-01-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One, 16, 2021
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8HCJ
| Structure of GH43 family enzyme, Xylan 1, 4 Beta- xylosidase from pseudopedobacter saltans | 分子名称: | CALCIUM ION, Xylan 1,4-beta-xylosidase | 著者 | Vishwakarma, P, Sachdeva, E, Goyal, A, Ethayathulla, A.S, Das, U, Kaur, P. | 登録日 | 2022-11-01 | 公開日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.566 Å) | 主引用文献 | Structure of GH43 family enzyme, Xylan 1, 4 Beta- xylosidase from pseudopedobacter saltans To Be Published
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6R2G
| Crystal structure of a single-chain protein mimetic of the gp41 NHR trimer in complex with the synthetic CHR peptide C34 | 分子名称: | Envelope glycoprotein gp160, PHOSPHATE ION, Single-chain protein mimetics of the N-terminal heptad-repeat region of gp41 | 著者 | Camara-Artigas, A, Conejero-Lara, F, Jurado, S, Cano-Munoz, M, Morel, B. | 登録日 | 2019-03-17 | 公開日 | 2019-07-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and Thermodynamic Analysis of HIV-1 Fusion Inhibition Using Small gp41 Mimetic Proteins. J.Mol.Biol., 431, 2019
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6JPL
| The X-ray structure of yeast tRNA methyltransferase Trm7-Trm734 in complex with S-adenosyl-L-methionine | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, S-ADENOSYLMETHIONINE, SULFATE ION, ... | 著者 | Hirata, A, Okada, K, Yoshii, K, Shiraisi, H, Saijo, S, Yonezawa, K, Shimizu, N, Hori, H. | 登録日 | 2019-03-27 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Structure of tRNA methyltransferase complex of Trm7 and Trm734 reveals a novel binding interface for tRNA recognition. Nucleic Acids Res., 47, 2019
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5IUS
| Crystal structure of human PD-L1 in complex with high affinity PD-1 mutant | 分子名称: | CHLORIDE ION, Programmed cell death 1 ligand 1, Programmed cell death protein 1 | 著者 | Pascolutti, R, Sun, X, Kao, J, Maute, R, Ring, A.M, Bowman, G.R, Kruse, A.C. | 登録日 | 2016-03-18 | 公開日 | 2016-09-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.889 Å) | 主引用文献 | Structure and Dynamics of PD-L1 and an Ultra-High-Affinity PD-1 Receptor Mutant. Structure, 24, 2016
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5APO
| Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and C-terminally tagged Rei1 | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, N. | 登録日 | 2015-09-17 | 公開日 | 2015-12-16 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | 主引用文献 | Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation. Cell(Cambridge,Mass.), 164, 2016
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4ZCH
| Single-chain human APRIL-BAFF-BAFF Heterotrimer | 分子名称: | TRIS-HYDROXYMETHYL-METHYL-AMMONIUM, Tumor necrosis factor ligand superfamily member 13,Tumor necrosis factor ligand superfamily member 13B,Tumor necrosis factor ligand superfamily member 13B | 著者 | Lammens, A, Jiang, X, Maskos, K, Schneider, P. | 登録日 | 2015-04-16 | 公開日 | 2015-05-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Stoichiometry of Heteromeric BAFF and APRIL Cytokines Dictates Their Receptor Binding and Signaling Properties. J.Biol.Chem., 290, 2015
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1ADD
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6CAC
| Crystal structure of NDM-1 metallo-beta-lactamase harboring an insertion of a Pro residue in L3 loop | 分子名称: | CADMIUM ION, CALCIUM ION, COBALT (II) ION, ... | 著者 | Alzari, P.M, Giannini, E, Palacios, A, Mojica, M, Bonomo, R, Llarrull, L, Vila, A. | 登録日 | 2018-01-30 | 公開日 | 2018-10-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | The Reaction Mechanism of Metallo-beta-Lactamases Is Tuned by the Conformation of an Active-Site Mobile Loop. Antimicrob. Agents Chemother., 63, 2019
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5J8H
| Structure of calmodulin in a complex with a peptide derived from a calmodulin-dependent kinase | 分子名称: | CALCIUM ION, Calmodulin, Eukaryotic elongation factor 2 kinase | 著者 | Alphonse, S, Lee, K, Piserchio, A, Tavares, C.D.J, Giles, D.H, Wellmann, R.M, Dalby, K.N, Ghose, R. | 登録日 | 2016-04-07 | 公開日 | 2016-09-07 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Basis for the Recognition of Eukaryotic Elongation Factor 2 Kinase by Calmodulin. Structure, 24, 2016
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6S59
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8TU9
| Cryo-EM structure of HGSNAT-acetyl-CoA complex at pH 7.5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYL COENZYME *A, Enhanced green fluorescent protein,Heparan-alpha-glucosaminide N-acetyltransferase,Isoform 2 of Heparan-alpha-glucosaminide N-acetyltransferase | 著者 | Navratna, V, Kumar, A, Mosalaganti, S. | 登録日 | 2023-08-15 | 公開日 | 2024-02-07 | 最終更新日 | 2024-09-11 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Structure of the human heparan-alpha-glucosaminide N -acetyltransferase (HGSNAT). Elife, 13, 2024
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6S5Z
| Structure of Rib R28N from Streptococcus pyogenes | 分子名称: | SODIUM ION, Surface protein R28 | 著者 | Whelan, F, Griffiths, S.C, Whittingham, J.L, Bateman, A, Potts, J.R. | 登録日 | 2019-07-02 | 公開日 | 2019-12-11 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Defining the remarkable structural malleability of a bacterial surface protein Rib domain implicated in infection. Proc.Natl.Acad.Sci.USA, 116, 2019
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6W5K
| 1.95 A resolution structure of Norovirus 3CL protease in complex with inhibitor 5g | 分子名称: | 3C-LIKE PROTEASE, N~2~-{[2-(3-chlorophenyl)-2-methylpropoxy]carbonyl}-N-{(1R,2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]-1-sulfanylpropan-2-yl}-L-leucinamide | 著者 | Lovell, S, Kashipathy, M.M, Battaile, K.P, Rathnayake, A.D, Kim, Y, Chang, K.O, Groutas, W.C. | 登録日 | 2020-03-13 | 公開日 | 2020-09-30 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure-Guided Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease. J.Med.Chem., 63, 2020
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5Z6O
| Crystal structure of Penicillium cyclopium protease | 分子名称: | CALCIUM ION, phenylmethanesulfonic acid, protease | 著者 | Ko, T.-P, Koszelak, S, Ng, J, Day, J, Greenwood, A, McPherson, A. | 登録日 | 2018-01-24 | 公開日 | 2018-02-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The crystallographic structure of the subtilisin protease from Penicillium cyclopium. Biochemistry, 36, 1997
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6GA1
| Bacteriorhodopsin, dark state, cell 1 | 分子名称: | 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, DECANE, ... | 著者 | Nass Kovacs, G, Colletier, J.-P, Gruenbein, M.L, Stensitzki, T, Batyuk, A, Carbajo, S, Doak, R.B, Ehrenberg, D, Foucar, L, Gasper, R, Gorel, A, Hilpert, M, Kloos, M, Koglin, J, Reinstein, J, Roome, C.M, Schlesinger, R, Seaberg, M, Shoeman, R.L, Stricker, M, Boutet, S, Haacke, S, Heberle, J, Domratcheva, T, Barends, T.R.M, Schlichting, I. | 登録日 | 2018-04-11 | 公開日 | 2019-04-24 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Three-dimensional view of ultrafast dynamics in photoexcited bacteriorhodopsin. Nat Commun, 10, 2019
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6RK3
| Solution structure of the ribosome Elongation Factor P (EF-P) from Staphylococcus aureus | 分子名称: | Elongation factor P | 著者 | Usachev, K, Fatkhullin, B, Gabdulkhakov, A, Khusainov, I, Golubev, A, Validov, S, Yusupova, G, Yusupov, M. | 登録日 | 2019-04-30 | 公開日 | 2020-03-11 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR and crystallographic structural studies of the Elongation factor P from Staphylococcus aureus. Eur.Biophys.J., 49, 2020
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