6CAC
Crystal structure of NDM-1 metallo-beta-lactamase harboring an insertion of a Pro residue in L3 loop
Summary for 6CAC
Entry DOI | 10.2210/pdb6cac/pdb |
Related | 3spu |
Descriptor | Metallo-beta-lactamase type 2, ZINC ION, CADMIUM ION, ... (8 entities in total) |
Functional Keywords | ndm-1, zn-containing protein, hydrolase |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 4 |
Total formula weight | 101637.08 |
Authors | Alzari, P.M.,Giannini, E.,Palacios, A.,Mojica, M.,Bonomo, R.,Llarrull, L.,Vila, A. (deposition date: 2018-01-30, release date: 2018-10-17, Last modification date: 2023-10-04) |
Primary citation | Palacios, A.R.,Mojica, M.F.,Giannini, E.,Taracila, M.A.,Bethel, C.R.,Alzari, P.M.,Otero, L.H.,Klinke, S.,Llarrull, L.I.,Bonomo, R.A.,Vila, A.J. The Reaction Mechanism of Metallo-beta-Lactamases Is Tuned by the Conformation of an Active-Site Mobile Loop. Antimicrob. Agents Chemother., 63:-, 2019 Cited by PubMed: 30348667DOI: 10.1128/AAC.01754-18 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.79 Å) |
Structure validation
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