6CAC
Crystal structure of NDM-1 metallo-beta-lactamase harboring an insertion of a Pro residue in L3 loop
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Metallo-beta-lactamase type 2 | polymer | 235 | 24842.9 | 4 | UniProt (C7C422) Pfam (PF00753) | Klebsiella pneumoniae | B2 metallo-beta-lactamase,Beta-lactamase type II,Metallo-beta-lactamase NDM-1,Metallo-beta-lactamase type II,New Delhi metallo-beta-lactamase-1,NDM-1 |
| 2 | CA, E, N, U (D, A, B, C) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | DA, F, O, V (D, A, B, C) | CADMIUM ION | non-polymer | 112.4 | 4 | Chemie (CD) | |||
| 4 | EA, G, H, P, W (D, A, B, C) | NICKEL (II) ION | non-polymer | 58.7 | 5 | Chemie (NI) | |||
| 5 | FA, I, Q, X (D, A, B, C) | COBALT (II) ION | non-polymer | 58.9 | 4 | Chemie (CO) | |||
| 6 | GA, J, R, Y (D, A, B, C) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 7 | AA, BA, HA, K, L... (C, D, A, B) | SULFATE ION | non-polymer | 96.1 | 9 | Chemie (SO4) | |||
| 8 | IA, JA, KA, LA (A, B, C, D) | water | water | 18.0 | 915 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 39 - 271 (UniProt: C7C422)
| PDB | External Database | Details |
|---|---|---|
| Gly 37 | - | expression tag |
| His 38 | - | expression tag |
| Pro 75 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 99371.7 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 2265.4 | |
| All* | Total formula weight | 101637.1 |
