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PDB: 89346 件

6GO1
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Crystal Structure of a Bacillus anthracis peptidoglycan deacetylase
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Polysaccharide deacetylase-like protein, ...
著者Giastas, P, Andreou, A, Eliopoulos, E.E.
登録日2018-06-01
公開日2019-04-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献The putative polysaccharide deacetylase Ba0331: cloning, expression, crystallization and structure determination.
Acta Crystallogr.,Sect.F, 75, 2019
1D81
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BU of 1d81 by Molmil
THE CONFORMATIONAL VARIABILITY OF AN ADENOSINE. INOSINE BASE-PAIR IN A SYNTHETIC DNA DODECAMER
分子名称: DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*IP*GP*CP*G)-3')
著者Leonard, G.A, Booth, E.D, Hunter, W.N, Brown, T.
登録日1992-07-07
公開日1992-10-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The conformational variability of an adenosine.inosine base-pair in a synthetic DNA dodecamer.
Nucleic Acids Res., 20, 1992
7TIB
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BU of 7tib by Molmil
Structure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp (Proliferating Cell Nuclear Antigen PCNA) and primer-template DNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*AP*GP*AP*CP*AP*CP*TP*AP*CP*GP*AP*GP*TP*AP*CP*AP*TP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*AP*TP*GP*TP*AP*CP*TP*CP*GP*TP*AP*GP*TP*GP*TP*CP*T)-3'), ...
著者Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A.
登録日2022-01-13
公開日2022-02-16
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader.
Elife, 11, 2022
1D88
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BU of 1d88 by Molmil
CONFORMATIONAL INFLUENCE OF THE RIBOSE 2'-HYDROXYL GROUP: CRYSTAL STRUCTURES OF DNA-RNA CHIMERIC DUPLEXES
分子名称: DNA/RNA (5'-D(*GP*CP*GP*TP*)-R(*AP*)-D(*TP*AP*CP*GP*C)-3')
著者Egli, M, Usman, N, Rich, A.
登録日1992-08-28
公開日1993-07-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Conformational influence of the ribose 2'-hydroxyl group: crystal structures of DNA-RNA chimeric duplexes.
Biochemistry, 32, 1993
8AO1
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BU of 8ao1 by Molmil
solution structure of nanoFAST fluorogen-activating protein in the apo state
分子名称: nanoFAST
著者Lushpa, V.A, Goncharuk, M.V, Goncharuk, S.A, Baranov, M.S, Mineev, K.S.
登録日2022-08-08
公開日2022-11-23
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Spatial Structure of NanoFAST in the Apo State and in Complex with its Fluorogen HBR-DOM2.
Int J Mol Sci, 23, 2022
7TID
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BU of 7tid by Molmil
Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen PCNA) and primer-template DNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*AP*GP*AP*CP*AP*CP*TP*AP*CP*GP*AP*GP*TP*AP*CP*AP*TP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*AP*TP*GP*TP*AP*CP*TP*CP*GP*TP*AP*GP*TP*GP*TP*CP*T)-3'), ...
著者Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A.
登録日2022-01-13
公開日2022-02-16
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader.
Elife, 11, 2022
4UFN
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BU of 4ufn by Molmil
Laboratory evolved variant R-C1B1 of potato epoxide hydrolase StEH1
分子名称: 1,4-DIETHYLENE DIOXIDE, EPOXIDE HYDROLASE
著者Carlsson, A.J, Bauer, P, Nilsson, M, Dobritzsch, D, Kamerlin, S.C.L, Widersten, M.
登録日2015-03-17
公開日2016-04-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Conformational Diversity and Enantioconvergence in Potato Epoxide Hydrolase 1.
Org.Biomol.Chem., 14, 2016
4YYT
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BU of 4yyt by Molmil
Human Carbonic Anhydrase II complexed with an inhibitor with a benzenesulfonamide group (5).
分子名称: 4-(2-hydroxyethyl)benzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ...
著者Rechlin, C, Heine, A, Klebe, G.
登録日2015-03-24
公開日2016-02-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Kinetic and Structural Insights into the Mechanism of Binding of Sulfonamides to Human Carbonic Anhydrase by Computational and Experimental Studies.
J.Med.Chem., 59, 2016
6RIH
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BU of 6rih by Molmil
Crystal structure of PHGDH in complex with compound 9
分子名称: D-3-phosphoglycerate dehydrogenase, SULFATE ION, ~{N}-cyclopropyl-2-methyl-5-phenyl-pyrazole-3-carboxamide
著者Bader, G, Wolkerstorfer, B, Zoephel, A.
登録日2019-04-24
公開日2019-08-07
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) InhibitorBI-4924Disrupts Serine Biosynthesis.
J.Med.Chem., 62, 2019
8GTR
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BU of 8gtr by Molmil
CryoEM structure of human Pannexin isoform 3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATIDYLETHANOLAMINE, Pannexin-3
著者Hussain, N, Penmatsa, A.
登録日2022-09-08
公開日2024-02-28
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Cryo-EM structures of pannexin 1 and 3 reveal differences among pannexin isoforms.
Nat Commun, 15, 2024
4YZP
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BU of 4yzp by Molmil
Crystal structure of a tri-modular GH5 (subfamily 4) endo-beta-1, 4-glucanase from Bacillus licheniformis
分子名称: Cellulose hydrolase
著者Liberato, M.V, Popov, A, Polikarpov, I.
登録日2015-03-25
公開日2016-09-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular characterization of a family 5 glycoside hydrolase suggests an induced-fit enzymatic mechanism.
Sci Rep, 6, 2016
4Z07
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BU of 4z07 by Molmil
Co-crystal structure of the tandem CNB (CNB-A/B) domains of human PKG I beta with cGMP
分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, ISOPROPYL ALCOHOL, SULFATE ION, ...
著者Kim, J.J, Reger, A.S, Arold, S.T, Kim, C.
登録日2015-03-25
公開日2016-04-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of PKG I:cGMP Complex Reveals a cGMP-Mediated Dimeric Interface that Facilitates cGMP-Induced Activation.
Structure, 24, 2016
8GBR
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BU of 8gbr by Molmil
Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
分子名称: Transthyretin
著者Nguyen, B.A, Saelices, L.
登録日2023-02-28
公開日2024-02-28
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis.
Commun Biol, 7, 2024
4UCP
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BU of 4ucp by Molmil
CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE (NMT) WITH BOUND MYRISTOYL-COA AND A FRAGMENT
分子名称: GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, N-methyl-1-[3-(morpholin-4-ylmethyl)phenyl]methanamine, TETRADECANOYL-COA
著者Robinson, D.A, Wyatt, P.G.
登録日2014-12-04
公開日2015-05-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Identification and Structure Solution of Fragment Hits Against Kinetoplastid N-Myristoyltransferase
Acta Crystallogr.,Sect.F, 71, 2015
3NRX
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BU of 3nrx by Molmil
Insights into anti-parallel microtubule crosslinking by PRC1, a conserved non-motor microtubule binding protein
分子名称: Protein regulator of cytokinesis 1
著者Kapoor, T.M, Subramanian, R, Wilson-Kubalek, E.M, Arthur, C.P, Bick, M.J, Campbell, E.A, Darst, S.A, Milligan, R.A.
登録日2010-06-30
公開日2010-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Insights into Antiparallel Microtubule Crosslinking by PRC1, a Conserved Nonmotor Microtubule Binding Protein.
Cell(Cambridge,Mass.), 142, 2010
8AO0
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BU of 8ao0 by Molmil
Solution structure of nanoFAST/HBR-DOM2 complex
分子名称: (5~{Z})-5-[(2,5-dimethoxy-4-oxidanyl-phenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, Photoactive yellow protein
著者Lushpa, V.A, Goncharuk, M.V, Goncharuk, S.A, Baleeva, N.S, Baranov, M.S, Mineev, K.S.
登録日2022-08-08
公開日2022-11-23
実験手法SOLUTION NMR
主引用文献Spatial Structure of NanoFAST in the Apo State and in Complex with its Fluorogen HBR-DOM2.
Int J Mol Sci, 23, 2022
5FGW
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BU of 5fgw by Molmil
Structure of Sda1 nuclease with bound zinc ion
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ...
著者Moon, A.F, Krahn, J.M, Xun, L, Cuneo, M.J, Pedersen, L.C.
登録日2015-12-21
公開日2016-03-30
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural characterization of the virulence factor Sda1 nuclease from Streptococcus pyogenes.
Nucleic Acids Res., 44, 2016
8GTT
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BU of 8gtt by Molmil
Cryo-EM structure of human Pannexin1 resembling Pannexin2 pore with W74R/R75Dmutations
分子名称: Pannexin-1
著者Hussain, N, Penmatsa, A.
登録日2022-09-08
公開日2024-02-28
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures of pannexin 1 and 3 reveal differences among pannexin isoforms.
Nat Commun, 15, 2024
8GTS
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BU of 8gts by Molmil
CryoEM structure of human Pannexin1 with R217H congenital mutation.
分子名称: Pannexin-1
著者Hussain, N, Penmatsa, A.
登録日2022-09-08
公開日2024-02-28
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.87 Å)
主引用文献Cryo-EM structures of pannexin 1 and 3 reveal differences among pannexin isoforms.
Nat Commun, 15, 2024
1CGL
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BU of 1cgl by Molmil
Structure of the catalytic domain of fibroblast collagenase complexed with an inhibitor
分子名称: CALCIUM ION, FIBROBLAST COLLAGENASE, N-[(1S)-3-{[(benzyloxy)carbonyl]amino}-1-carboxypropyl]-L-leucyl-N-(2-morpholin-4-ylethyl)-L-phenylalaninamide, ...
著者Lovejoy, B, Cleasby, A, Hassell, A.M, Longley, K, Luther, M.A, Weigl, D, Mcgeehan, G, Mcelroy, A.B, Drewry, D, Lambert, M.H, Jordan, S.R.
登録日1993-11-17
公開日1995-02-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the catalytic domain of fibroblast collagenase complexed with an inhibitor.
Science, 263, 1994
6RIY
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BU of 6riy by Molmil
Crystal structure of MchDnaB-1 intein (N145AA)
分子名称: CHLORIDE ION, Replicative DNA helicase
著者Beyer, H.M, Lountos, G.T, Mikula, M.K, Wlodawer, A, Iwai, H.
登録日2019-04-25
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献The Convergence of the Hedgehog/Intein Fold in Different Protein Splicing Mechanisms.
Int J Mol Sci, 21, 2020
6GKI
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BU of 6gki by Molmil
Structure of E coli MlaC in Variously Loaded States
分子名称: BROMIDE ION, GLYCEROL, Probable phospholipid-binding protein MlaC
著者Knowles, T.J, Lovering, A.L.
登録日2018-05-21
公開日2019-04-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Evidence for phospholipid export from the bacterial inner membrane by the Mla ABC transport system.
Nat Microbiol, 4, 2019
3MA6
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BU of 3ma6 by Molmil
Crystal structure of kinase domain of TgCDPK1 in presence of 3BrB-PP1
分子名称: 3-(3-bromobenzyl)-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1
著者Wernimont, A.K, Qiu, W, Amani, M, Artz, J.D, Hassani, A.A, Senisterra, G, Vedadi, M, Sibley, L.D, Lourido, S, Shokat, K, Zhang, C, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Hui, R, Lin, Y.H, Structural Genomics Consortium (SGC)
登録日2010-03-23
公開日2010-07-21
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of kinase domain of TgCDPK1 in presence of 3BrB-PP1
To be Published
8AID
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BU of 8aid by Molmil
Crystal structure of N-terminally truncated PA4183 from P. aeruginosa PAO1
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, PA4183
著者Popp, M.A, Blankenfeldt, W.
登録日2022-07-26
公開日2022-11-30
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Structure of N-terminally truncated PA4183 from P. aeruginosa PAO1
To Be Published
8TDH
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BU of 8tdh by Molmil
Structure of trehalose bound Alistipes sp. Glucoside-3-dehydrogenase AL3
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Predicted dehydrogenases and related proteins, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose
著者Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J.
登録日2023-07-03
公開日2024-06-19
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献An alternative broad-specificity pathway for glycan breakdown in bacteria.
Nature, 631, 2024

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件を2024-10-09に公開中

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