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PDB: 89832 件

7NC4
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Crystal structure of human carbonic anhydrase VII (hCA VII) in complex with a 4-(4-aroylpiperazine-1-carbonyl)benzenesulfonamide derivative.
分子名称: 4-[4-(2-chlorophenyl)carbonylpiperazin-1-yl]carbonylbenzenesulfonamide, Carbonic anhydrase 7, GLYCEROL, ...
著者Di Fiore, A, De Simone, G.
登録日2021-01-28
公開日2021-07-14
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Design, synthesis and biochemical evaluation of novel carbonic anhydrase inhibitors triggered by structural knowledge on hCA VII.
Bioorg.Med.Chem., 44, 2021
6YNJ
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Crystal structure of YTHDC1 with compound DHU_DC1_046
分子名称: (2~{R})-2-(2-chlorophenyl)-5,5-dimethyl-morpholine, SULFATE ION, YTHDC1
著者Bedi, R.K, Huang, D, Wiedmer, L, Caflisch, A.
登録日2020-04-13
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure-based design of ligands of the m6A-RNA reader YTHDC1
Eur J Med Chem Rep, 5, 2022
6YNN
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Crystal structure of YTHDC1 with compound DHU_DC1_135
分子名称: 6-[[(2-chloranyl-6-fluoranyl-phenyl)methyl-methyl-amino]methyl]-1~{H}-pyrimidine-2,4-dione, SULFATE ION, YTHDC1
著者Bedi, R.K, Huang, D, Wiedmer, L, Caflisch, A.
登録日2020-04-14
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
6I5Z
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BU of 6i5z by Molmil
Papaver somniferum O-methyltransferase
分子名称: O-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, S-ADENOSYLMETHIONINE
著者Davies, G.J, Cabry, M.P, Offen, W.A.
登録日2018-11-15
公開日2019-03-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of Papaver somniferum O-Methyltransferase 1 Reveals Initiation of Noscapine Biosynthesis with Implications for Plant Natural Product Methylation
Acs Catalysis, 2019
6MAT
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BU of 6mat by Molmil
Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Rix7 mutant, unknown protein
著者Lo, Y.H, Sobhany, M, Hsu, A.L, Ford, B.L, Krahn, J.M, Borgnia, M.J, Stanley, R.E.
登録日2018-08-28
公開日2019-02-06
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7.
Nat Commun, 10, 2019
5MPB
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BU of 5mpb by Molmil
26S proteasome in presence of AMP-PNP (s3)
分子名称: 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ...
著者Wehmer, M, Rudack, T, Beck, F, Aufderheide, A, Pfeifer, G, Plitzko, J.M, Foerster, F, Schulten, K, Baumeister, W, Sakata, E.
登録日2016-12-16
公開日2017-03-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献Structural insights into the functional cycle of the ATPase module of the 26S proteasome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3E0K
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BU of 3e0k by Molmil
Crystal structure of C-termianl domain of N-acetylglutamate synthase from Vibrio parahaemolyticus
分子名称: 1,2-ETHANEDIOL, Amino-acid acetyltransferase, SULFATE ION
著者Chang, C, Shackelford, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2008-07-31
公開日2008-08-19
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Crystal structure of C-termianl domain of N-acetylglutamate synthase from Vibrio parahaemolyticus
To be Published
6YQ6
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BU of 6yq6 by Molmil
Promiscuous Reductase LugOII Catalyzes Keto-reduction at C1 during Lugdunomycin Biosynthesis
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Monooxygenase, ...
著者Xiao, X, Elsayed, S.S, Wu, C, van der Heul, H, Prota, A, Huang, J, Guo, R, Abrahams, J.P, van Wezel, G.P.
登録日2020-04-16
公開日2020-09-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Functional and Structural Insights into a Novel Promiscuous Ketoreductase of the Lugdunomycin Biosynthetic Pathway.
Acs Chem.Biol., 15, 2020
4WY2
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BU of 4wy2 by Molmil
Crystal structure of universal stress protein E from Proteus mirabilis in complex with UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetyl-alpha-glucosamine
分子名称: CHLORIDE ION, GLYCEROL, SULFATE ION, ...
著者Shumilin, I.A, Shabalin, I.G, Handing, K.B, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2014-11-15
公開日2014-11-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of universal stress protein E from Proteus mirabilis incomplex withUDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetyl-alpha-glucosamine
to be published
6SJT
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BU of 6sjt by Molmil
Crystal structure of the Legionella pneumophila type II secretion system substrate NttC
分子名称: NttC
著者Portlock, T.J, Rehman, S, Garnett, J.A.
登録日2019-08-13
公開日2020-05-20
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.103 Å)
主引用文献Structure, Dynamics and Cellular Insight Into Novel Substrates of theLegionella pneumophilaType II Secretion System.
Front Mol Biosci, 7, 2020
5MPI
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Structural Basis of Gene Regulation by the Grainyhead Transcription Factor Superfamily
分子名称: Grainyhead-like protein 1 homolog
著者Ming, Q, Roske, Y, Schuetz, A, Walentin, K, Ibraimi, I, Schmidt-Ott, K.M, Heinemann, U.
登録日2016-12-16
公開日2018-01-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.345 Å)
主引用文献Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family.
Nucleic Acids Res., 46, 2018
6PFJ
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BU of 6pfj by Molmil
Structure of S. venezuelae RsiG-WhiG-(ci-di-GMP) complex, P64 crystal form
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), AmfC protein, RNA polymerase sigma factor
著者Schumacher, M.A.
登録日2019-06-21
公開日2019-11-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献c-di-GMP Arms an Anti-sigma to Control Progression of Multicellular Differentiation in Streptomyces.
Mol.Cell, 77, 2020
8E55
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BU of 8e55 by Molmil
Design of Diverse Asymmetric Pockets in de novo Homo-oligomeric Proteins
分子名称: SG135
著者Gerben, S, Borst, A.J, Baker, D.
登録日2022-08-19
公開日2023-01-25
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.85 Å)
主引用文献Design of Diverse Asymmetric Pockets in De Novo Homo-oligomeric Proteins.
Biochemistry, 62, 2023
4H8V
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BU of 4h8v by Molmil
Crystal structure of the trehalulose synthase MUTB in complex with trehalulose
分子名称: 1-O-alpha-D-glucopyranosyl-D-fructose, CALCIUM ION, Sucrose isomerase
著者Lipski, A, Ravaud, S, Haser, R, Aghajari, N.
登録日2012-09-24
公開日2013-09-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Insights into product binding in sucrose isomerases from crystal structures of MutB from Rhizobium sp.
To be Published
6S8F
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BU of 6s8f by Molmil
Structure of nucleotide-bound Tel1/ATM
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1
著者Yates, L.A, Williams, R.M, Ayala, R, Zhang, X.
登録日2019-07-09
公開日2019-10-30
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM Structure of Nucleotide-Bound Tel1ATMUnravels the Molecular Basis of Inhibition and Structural Rationale for Disease-Associated Mutations.
Structure, 28, 2020
8DZG
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BU of 8dzg by Molmil
Cryo-EM structure of bundle-forming pilus extension ATPase from E.coli in the presence of ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, BfpD, MAGNESIUM ION, ...
著者Nayak, A.R, Zhao, J, Donnenberg, M.S, Samso, M.
登録日2022-08-07
公開日2022-10-26
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM Structure of the Type IV Pilus Extension ATPase from Enteropathogenic Escherichia coli.
Mbio, 13, 2022
6M9J
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BU of 6m9j by Molmil
Racemic-GSTSTA from degenerate octameric repeats in InaZ, residues 707-712
分子名称: Ice nucleation protein
著者Zee, C, Glynn, C, Gallagher-Jones, M, Miao, J, Santiago, C.G, Cascio, D, Gonen, T, Sawaya, M.R, Rodriguez, J.A.
登録日2018-08-23
公開日2019-03-27
最終更新日2024-03-13
実験手法ELECTRON CRYSTALLOGRAPHY (0.9 Å)
主引用文献Homochiral and racemic MicroED structures of a peptide repeat from the ice-nucleation protein InaZ.
IUCrJ, 6, 2019
8JQ3
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BU of 8jq3 by Molmil
Crystal structure of L-rhamnose isomerase from Lactobacillus rhamnosus
分子名称: L-rhamnose isomerase, MANGANESE (II) ION
著者Yoshida, H, Yoshihara, A.
登録日2023-06-13
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-ray structure and characterization of a probiotic Lactobacillus rhamnosus Probio-M9 L-rhamnose isomerase.
Appl.Microbiol.Biotechnol., 108, 2024
8AFX
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BU of 8afx by Molmil
Single particle structure of Atg18-WT
分子名称: Autophagy-related protein 18
著者Mann, D, Fromm, S, Martinez-Sanchez, A, Gopaldass, N, Mayer, A, Sachse, C.
登録日2022-07-18
公開日2024-01-31
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Atg18 oligomer organization in assembled tubes and on lipid membrane scaffolds.
Nat Commun, 14, 2023
7RGW
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Crystal structure of HERC2 DOC domain
分子名称: DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase HERC2
著者Liu, J, Tencer, A.H, Kutateladze, T.G.
登録日2021-07-15
公開日2022-07-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The ZZ domain of HERC2 is a receptor of arginylated substrates.
Sci Rep, 12, 2022
1DMB
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BU of 1dmb by Molmil
REFINED 1.8 ANGSTROMS STRUCTURE REVEALS THE MECHANISM OF BINDING OF A CYCLIC SUGAR, BETA-CYCLODEXTRIN, TO THE MALTODEXTRIN BINDING PROTEIN
分子名称: Cycloheptakis-(1-4)-(alpha-D-glucopyranose), D-MALTODEXTRIN BINDING PROTEIN
著者Sharff, A.J, Quiocho, F.A.
登録日1993-06-10
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Refined 1.8-A structure reveals the mode of binding of beta-cyclodextrin to the maltodextrin binding protein.
Biochemistry, 32, 1993
5MSZ
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Lytic Polysaccharide Monooxygenase AA15 from Thermobia domestica in the Cu(I) State
分子名称: 1,2-ETHANEDIOL, COPPER (I) ION, Thermobia domestica domestica AA15
著者Hemsworth, G.R, Sabbadin, F, Ciano, L, Henrissat, B, Dupree, P, Tryfona, T, Besser, K, Elias, L, Pesante, G, Li, Y, Dowle, A, Bates, R, Gomez, L, Hallam, R, Davies, G.J, Walton, P.H, Bruce, N.C, McQueen-Mason, S.
登録日2017-01-06
公開日2018-02-28
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献An ancient family of lytic polysaccharide monooxygenases with roles in arthropod development and biomass digestion.
Nat Commun, 9, 2018
5MT0
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COMPLEMENT FACTOR D IN COMPLEX WITH A REVERSIBLE INDOLE CARBOXYLIC ACID BASED INHIBITOR
分子名称: 5-fluoranyl-3-[[(1~{S},2~{S})-2-phenylcyclopropyl]carbonylamino]-1~{H}-indole-2-carboxylic acid, Complement factor D, SULFATE ION
著者Mac Sweeney, A, Ostermann, N.
登録日2017-01-06
公開日2017-02-15
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Structure-Based Library Design and Fragment Screening for the Identification of Reversible Complement Factor D Protease Inhibitors.
J. Med. Chem., 60, 2017
3NEI
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BU of 3nei by Molmil
Crystal structure of Precorrin-4 C11-methyltransferase from Rhodobacter capsulatus (no SAH bound)
分子名称: GLYCEROL, Precorrin-4 C(11)-methyltransferase, SULFATE ION
著者Seyedarabi, A, Pickersgill, R.W.
登録日2010-06-08
公開日2011-06-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of Precorrin-4 C11-methyltransferase from Rhodobacter capsulatus (no SAH bound)
To be Published
5FAA
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BU of 5faa by Molmil
Crystal structure of C-terminal domain of shaft pilin spaA from Lactobacillus rhamnosus GG, - I422 space group
分子名称: 1,2-ETHANEDIOL, Cell surface protein SpaA
著者Chaurasia, P, Pratap, S, von Ossowski, I, Palva, A, Krishnan, V.
登録日2015-12-11
公開日2016-07-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献New insights about pilus formation in gut-adapted Lactobacillus rhamnosus GG from the crystal structure of the SpaA backbone-pilin subunit
Sci Rep, 6, 2016

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