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PDB: 88675 件

6XWQ
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Structure of glutamate transporter homologue GltTk in the saturated conditions
分子名称: ASPARTIC ACID, Proton/glutamate symporter, SDF family
著者Arkhipova, V, Slotboom, D.J, Guskov, A.
登録日2020-01-24
公開日2020-03-04
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Structural ensemble of a glutamate transporter homologue in lipid nanodisc environment.
Nat Commun, 11, 2020
5N52
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Crystal structure of human Pim-1 kinase in complex with a consensus peptide and fragment like molecule (E)-3-(2,3-dimethoxyphenyl)acrylic acid
分子名称: (~{E})-3-(2,3-dimethoxyphenyl)prop-2-enoic acid, Pimtide, Serine/threonine-protein kinase pim-1
著者Siefker, C, Heine, A, Klebe, G.
登録日2017-02-11
公開日2018-02-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.252 Å)
主引用文献A crystallographic fragment study with human Pim-1 kinase
to be published
7SRK
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Single chain trimer HLA-A*24:02 (Y108C, A163C) with 8mer peptide YPPVPETF
分子名称: RPA-related protein RADX peptide,Beta-2-microglobulin,MHC class I antigen chimera, VHH
著者Finton, K.A.K, Rupert, P.B.
登録日2021-11-08
公開日2022-11-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Effects of HLA single chain trimer design on peptide presentation and stability.
Front Immunol, 14, 2023
8D1U
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E. coli beta-ketoacyl-[acyl carrier protein] synthase III (FabH) with an acetylated cysteine and in complex with oxa(dethia)-Coenzyme A
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 3, CHLORIDE ION, oxa(dethia)-CoA
著者Benjamin, A.B, Stunkard, L.M, Ling, J, Nice, J.N, Lohman, J.R.
登録日2022-05-27
公開日2022-06-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.302 Å)
主引用文献Structures of chloramphenicol acetyltransferase III and Escherichia coli beta-ketoacylsynthase III co-crystallized with partially hydrolysed acetyl-oxa(dethia)CoA.
Acta Crystallogr.,Sect.F, 79, 2023
7QIM
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In situ structure of nebulin bound to actin filament in skeletal sarcomere
分子名称: ACTS protein, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Wang, Z, Grange, M, Pospich, S, Wagner, T, Kho, A.L, Gautel, M, Raunser, S.
登録日2021-12-15
公開日2022-03-16
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structures from intact myofibrils reveal mechanism of thin filament regulation through nebulin.
Science, 375, 2022
4YN8
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Crystal Structure of Response Regulator ChrA in Heme-Sensing Two Component System
分子名称: MAGNESIUM ION, Response regulator ChrA, SULFATE ION
著者Doi, A, Nakamura, H, Shiro, Y, Sugimoto, H.
登録日2015-03-09
公開日2015-08-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the response regulator ChrA in the haem-sensing two-component system of Corynebacterium diphtheriae.
Acta Crystallogr.,Sect.F, 71, 2015
8D5I
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BU of 8d5i by Molmil
Crystal structure of dihydropteroate synthase H182G mutant (folP-SMZ_B27) from soil uncultured bacterium in complex with pteroic acid and pyrophosphate
分子名称: PTEROIC ACID, PYROPHOSPHATE 2-, folP-SMZ_B27
著者Stogios, P.J, Skarina, T, Kim, Y, Di Leo, R, Venkatesan, M, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2022-06-04
公開日2022-06-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Crystal structure of dihydropteroate synthase H182G mutant (folP-SMZ_B27) from soil uncultured bacterium in complex with pteroic acid
To Be Published
7SR4
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Single chain trimer HLA-A*02:01 (H98L, Y108C) with HPV.16 E7 peptide YMLDLQPETTDLYC
分子名称: Protein E7 peptide,Beta-2-microglobulin,MHC class I antigen chimera, VHH
著者Finton, K.A.K, Rupert, P.B.
登録日2021-11-07
公開日2022-11-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Effects of HLA single chain trimer design on peptide presentation and stability.
Front Immunol, 14, 2023
5K3K
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Crystal structure of laccase from Thermus thermophilus HB27 (CuSO4, 20 min)
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, COPPER (II) ION, ...
著者Diaz-Vilchis, A, Ruiz-Arellano, R.R, Rosas-Benitez, E, Rudino-Pinera, E.
登録日2016-05-19
公開日2017-05-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.644 Å)
主引用文献Preserving metallic sites affected by radiation damage: the CuT2 case in Thermus thermophilus multicopper oxidase
To be Published
6X8T
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BU of 6x8t by Molmil
CryoEM structure of the apo-SrpI encapasulin complex from Synechococcus elongatus PCC 7942
分子名称: Protein SrpI
著者LaFrance, B.J, Nichols, R.J, Phillips, N.R, Oltrogge, L.M, Valentin-Alvarado, L.E, Bischoff, A.J, Savage, D.F, Nogales, E.
登録日2020-06-01
公開日2020-06-10
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Discovery and characterization of a novel family of prokaryotic nanocompartments involved in sulfur metabolism.
Elife, 10, 2021
6QWK
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BU of 6qwk by Molmil
The Transcriptional Regulator PrfA-L140F mutant from Listeria Monocytogenes in complex with a 30-bp operator PrfA-box motif
分子名称: DNA (30-MER), GLYCEROL, Listeriolysin positive regulatory factor A
著者Hall, M, Grundstrom, C, Hansen, S, Brannstrom, K, Johansson, J, Sauer-Eriksson, A.E.
登録日2019-03-05
公開日2020-04-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A Novel Growth-Based Selection Strategy Identifies New Constitutively Active Variants of the Major Virulence Regulator PrfA in Listeria monocytogenes.
J.Bacteriol., 202, 2020
7ODW
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BU of 7odw by Molmil
Model of Haliangium ochraceum encapsulin from icosahedral single particle reconstruction
分子名称: Linocin_M18 bacteriocin protein
著者Marles-Wright, J, Basle, A, Clarke, D.J, Ross, J.
登録日2021-04-30
公開日2022-03-09
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Pore dynamics and asymmetric cargo loading in an encapsulin nanocompartment.
Sci Adv, 8, 2022
7SR0
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Single chain trimer HLA-A*02:01 (H98L, Y108C) with HPV.16 E7 peptide YMLDLQPET
分子名称: PHOSPHATE ION, Protein E7 peptide,Beta-2-microglobulin,MHC class I antigen chimera, VHH
著者Finton, K.A.K, Rupert, P.B.
登録日2021-11-07
公開日2022-11-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Effects of HLA single chain trimer design on peptide presentation and stability.
Front Immunol, 14, 2023
6N3X
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BU of 6n3x by Molmil
Human Histidine Triad Nucleotide Binding Protein 1 (Hint1) with Bound 5'-O-[1-Benzyl]Carbamoyl Guanosine
分子名称: 1,2-ETHANEDIOL, 5'-O-(benzylcarbamoyl)guanosine, CHLORIDE ION, ...
著者Strom, A.M, Finzel, B.C.
登録日2018-11-16
公開日2019-09-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Inhibition of HINT1 Modulates Spinal Nociception and NMDA Evoked Behavior in Mice.
Acs Chem Neurosci, 10, 2019
5NCL
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BU of 5ncl by Molmil
Crystal structure of the Cbk1-Mob2 kinase-coactivator complex with an SSD1 peptide
分子名称: CBK1 kinase activator protein MOB2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Protein SSD1, ...
著者Gogl, G, Remenyi, A, Parker, B, Weiss, E.
登録日2017-03-06
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Ndr/Lats Kinases Bind Specific Mob-Family Coactivators through a Conserved and Modular Interface.
Biochemistry, 2020
7SR3
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BU of 7sr3 by Molmil
Single chain trimer HLA-A*02:01 (H98L, Y108C) with HPV.16 E7 peptide YMLDLQPETTDL
分子名称: Protein E7 peptide,Beta-2-microglobulin,MHC class I antigen chimera, VHH
著者Finton, K.A.K, Rupert, P.B.
登録日2021-11-07
公開日2022-11-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Effects of HLA single chain trimer design on peptide presentation and stability.
Front Immunol, 14, 2023
6R24
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BU of 6r24 by Molmil
The structure of a Ty3 retrotransposon icosahedral capsid
分子名称: Transposon Ty3-I Gag-Pol polyprotein
著者Dodonova, S.O, Prinz, S, Bilanchone, V, Sandmeyer, S, Briggs, J.A.G.
登録日2019-03-15
公開日2019-05-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (7.5 Å)
主引用文献Structure of the Ty3/Gypsy retrotransposon capsid and the evolution of retroviruses.
Proc.Natl.Acad.Sci.USA, 116, 2019
6N52
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Metabotropic Glutamate Receptor 5 Apo Form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5
著者Koehl, A, Hu, H, Feng, D, Sun, B, Weis, W.I, Skiniotis, G.S, Mathiesen, J.M, Kobilka, B.K.
登録日2018-11-20
公開日2019-01-23
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural insights into the activation of metabotropic glutamate receptors.
Nature, 566, 2019
5K75
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IRAK4 in complex with Compound 1
分子名称: Interleukin-1 receptor-associated kinase 4, SULFATE ION, ~{N}1-(7,8-dihydro-6~{H}-cyclopenta[2,3]thieno[2,4-~{c}]pyrimidin-1-yl)-~{N}4,~{N}4-dimethyl-cyclohexane-1,4-diamine
著者Ferguson, A.D.
登録日2016-05-25
公開日2017-12-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Discovery and Optimization of Pyrrolopyrimidine Inhibitors of Interleukin-1 Receptor Associated Kinase 4 (IRAK4) for the Treatment of Mutant MYD88L265P Diffuse Large B-Cell Lymphoma.
J. Med. Chem., 60, 2017
5MZ6
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BU of 5mz6 by Molmil
Cryo-EM structure of a Separase-Securin complex from Caenorhabditis elegans at 3.8 A resolution
分子名称: Interactor of FizzY protein, SEParase
著者Boland, A, Martin, T.G, Zhang, Z, Yang, J, Bai, X.C, Chang, L, Scheres, S.H.W, Barford, D.
登録日2017-01-31
公開日2017-03-08
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structure of a metazoan separase-securin complex at near-atomic resolution.
Nat. Struct. Mol. Biol., 24, 2017
7ZYF
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BU of 7zyf by Molmil
Insulin regulated aminopeptidase (IRAP) in complex with a nanomolar alpha hydroxy beta amino acid based inhibitor.
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Mpakali, A, Stratikos, E, Giastas, P, Papakyriakou, A.
登録日2022-05-24
公開日2022-07-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Discovery of Selective Nanomolar Inhibitors for Insulin-Regulated Aminopeptidase Based on alpha-Hydroxy-beta-amino Acid Derivatives of Bestatin.
J.Med.Chem., 65, 2022
6GAC
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BU of 6gac by Molmil
BACTERIORHODOPSIN, 490 FS STATE, REAL-SPACE REFINED AGAINST 15% EXTRAPOLATED STRUCTURE FACTORS
分子名称: 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, DECANE, ...
著者Nass Kovacs, G, Colletier, J.-P, Gruenbein, M.L, Stensitzki, T, Batyuk, A, Carbajo, S, Doak, R.B, Ehrenberg, D, Foucar, L, Gasper, R, Gorel, A, Hilpert, M, Kloos, M, Koglin, J, Reinstein, J, Roome, C.M, Schlesinger, R, Seaberg, M, Shoeman, R.L, Stricker, M, Boutet, S, Haacke, S, Heberle, J, Domratcheva, T, Schlichting, I.
登録日2018-04-11
公開日2019-04-24
最終更新日2019-07-31
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Three-dimensional view of ultrafast dynamics in photoexcited bacteriorhodopsin.
Nat Commun, 10, 2019
5K84
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Crystal structure of laccase from Thermus thermophilus HB27 (sodium nitrate 10 min)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, COPPER (II) ION, Laccase
著者Diaz-Vilchis, A, Ruiz-Arellano, R.R, Rosas-Benitez, E, Rudino-Pinera, E.
登録日2016-05-27
公開日2017-06-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Preserving metallic sites affected by radiation damage: the CuT2 case in Thermus thermophilus multicopper oxidase
To be Published
6V88
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Solution NMR structure of Dictyostelium discoideum Skp1A (truncated) dimer
分子名称: SCF ubiquitin ligase complex protein SKP1a
著者Kim, H.W, Eletsky, A, West, C.M.
登録日2019-12-10
公開日2020-04-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Skp1 Dimerization Conceals Its F-Box Protein Binding Site.
Biochemistry, 59, 2020
5LZX
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Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a UGA stop codon.
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
著者Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
登録日2016-10-02
公開日2016-11-30
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016

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件を2024-07-31に公開中

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